From α acetylthioformanilide and thio semicarbazide eight heterocyclic compounds of substituted phenylamino 6 metyl 1,2,4 triazine 3 thiones were synthesized.Their structures were confirmed by elemental analysis, 1HN...From α acetylthioformanilide and thio semicarbazide eight heterocyclic compounds of substituted phenylamino 6 metyl 1,2,4 triazine 3 thiones were synthesized.Their structures were confirmed by elemental analysis, 1HNMR,IR and MS.展开更多
3,4-Dihydropyrimidin-2-(1H)-ones were synthesized in high yields by a one-pot cyclocondensation of aldehyde,1,3-dicarbonyl compound,and urea or thiourea using copper o-toluenesulfonate as a catalyst under solvent-free...3,4-Dihydropyrimidin-2-(1H)-ones were synthesized in high yields by a one-pot cyclocondensation of aldehyde,1,3-dicarbonyl compound,and urea or thiourea using copper o-toluenesulfonate as a catalyst under solvent-free conditions at 90℃.Effects of molar ratio of reactants,amount of catalyst,and reaction temperature on the yields of 3,4-dihydropyrimidin-2-(1H)-ones were investigated.The results showed that at the condition of naldehyde∶n1,3-dicarbonyl compounds∶nurea(or thiourea)=1∶1.2∶1.5,1 mol% catalyst(molar percent of aldehyde),2.0 h at 90℃,the yields of products were 51-96%.After reaction,the catalyst could be reused for four times without distinct loss of catalytic activity.展开更多
文摘From α acetylthioformanilide and thio semicarbazide eight heterocyclic compounds of substituted phenylamino 6 metyl 1,2,4 triazine 3 thiones were synthesized.Their structures were confirmed by elemental analysis, 1HNMR,IR and MS.
文摘3,4-Dihydropyrimidin-2-(1H)-ones were synthesized in high yields by a one-pot cyclocondensation of aldehyde,1,3-dicarbonyl compound,and urea or thiourea using copper o-toluenesulfonate as a catalyst under solvent-free conditions at 90℃.Effects of molar ratio of reactants,amount of catalyst,and reaction temperature on the yields of 3,4-dihydropyrimidin-2-(1H)-ones were investigated.The results showed that at the condition of naldehyde∶n1,3-dicarbonyl compounds∶nurea(or thiourea)=1∶1.2∶1.5,1 mol% catalyst(molar percent of aldehyde),2.0 h at 90℃,the yields of products were 51-96%.After reaction,the catalyst could be reused for four times without distinct loss of catalytic activity.
