The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halog...The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.展开更多
A series of 2-phenyliminothiazolidines has been successfully synthesized; and 2-(2-methylphenyl)iminothiazolidine(Ⅰa) and 2-(4-methylphenyl) iminothiazolidine(Ⅰb) have been selected to determine their crystal struct...A series of 2-phenyliminothiazolidines has been successfully synthesized; and 2-(2-methylphenyl)iminothiazolidine(Ⅰa) and 2-(4-methylphenyl) iminothiazolidine(Ⅰb) have been selected to determine their crystal structures by X-ray diffraction technique, from their molecular graph of it is shown that double bond at 2-carbon atom of the heterocycle is all extro-cyclic at the crystal state, and there are two main plaines in Ⅰa and Ⅰb . But in Ⅰa , the angle between the planes is 61.4° and in Ⅰb the angle is about 41.4°. And so there is a strong conjugative effect in Ⅰb than in Ⅰa. So it is thought that the difference in fungicidal activies between 2-substitutedphenyl compounds(Ⅰa) and 4-substitutedphenyl compounds(Ⅰb) is due to their space factors.展开更多
采用"半胱氨酸-木糖"模型反应,在p H 5.5、温度分别为120、130、140、150、160℃的条件下,考察初始美拉德中间体2-木糖基噻唑烷-4-羧酸、半胱氨酸-Amadori及原料半胱氨酸的含量随反应时间的变化,发现2-木糖基噻唑烷-4-羧酸、...采用"半胱氨酸-木糖"模型反应,在p H 5.5、温度分别为120、130、140、150、160℃的条件下,考察初始美拉德中间体2-木糖基噻唑烷-4-羧酸、半胱氨酸-Amadori及原料半胱氨酸的含量随反应时间的变化,发现2-木糖基噻唑烷-4-羧酸、半胱氨酸的含量在各个温度下均呈下降趋势,温度越高下降越快;但半胱氨酸Amadori的含量在120、130、140℃时呈钟形曲线变化,150、160℃则一直呈陡峭的下降趋势。比较半胱氨酸利用率、反应产物的颜色、气味特征和检测到的挥发性化合物总量,尤其含硫化合物的量,得出采用140℃反应60 min为模型反应较佳条件。采用双柱定性、保留指数比对、标准谱库检索,从140℃反应60 min的产物中检测出含硫化合物40种,含氮杂环化合物5种,含氧杂环化合物8种,含量较高的为2-甲基-3-呋喃硫醇、2-糠硫醇、2-噻吩硫醇、2-甲基噻吩并[2,3-b]噻吩、2,5-噻吩二甲醛等。展开更多
文摘The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.
文摘A series of 2-phenyliminothiazolidines has been successfully synthesized; and 2-(2-methylphenyl)iminothiazolidine(Ⅰa) and 2-(4-methylphenyl) iminothiazolidine(Ⅰb) have been selected to determine their crystal structures by X-ray diffraction technique, from their molecular graph of it is shown that double bond at 2-carbon atom of the heterocycle is all extro-cyclic at the crystal state, and there are two main plaines in Ⅰa and Ⅰb . But in Ⅰa , the angle between the planes is 61.4° and in Ⅰb the angle is about 41.4°. And so there is a strong conjugative effect in Ⅰb than in Ⅰa. So it is thought that the difference in fungicidal activies between 2-substitutedphenyl compounds(Ⅰa) and 4-substitutedphenyl compounds(Ⅰb) is due to their space factors.
文摘采用"半胱氨酸-木糖"模型反应,在p H 5.5、温度分别为120、130、140、150、160℃的条件下,考察初始美拉德中间体2-木糖基噻唑烷-4-羧酸、半胱氨酸-Amadori及原料半胱氨酸的含量随反应时间的变化,发现2-木糖基噻唑烷-4-羧酸、半胱氨酸的含量在各个温度下均呈下降趋势,温度越高下降越快;但半胱氨酸Amadori的含量在120、130、140℃时呈钟形曲线变化,150、160℃则一直呈陡峭的下降趋势。比较半胱氨酸利用率、反应产物的颜色、气味特征和检测到的挥发性化合物总量,尤其含硫化合物的量,得出采用140℃反应60 min为模型反应较佳条件。采用双柱定性、保留指数比对、标准谱库检索,从140℃反应60 min的产物中检测出含硫化合物40种,含氮杂环化合物5种,含氧杂环化合物8种,含量较高的为2-甲基-3-呋喃硫醇、2-糠硫醇、2-噻吩硫醇、2-甲基噻吩并[2,3-b]噻吩、2,5-噻吩二甲醛等。
