L-Lysine was produced by a microbial process utilizing a Corynebacterium glutamicum （ATCC 21799） strain. L-Lysine was purified from the cultivated medium by fixed-bed and simulated moving bed （SMB） chromatography....L-Lysine was produced by a microbial process utilizing a Corynebacterium glutamicum （ATCC 21799） strain. L-Lysine was purified from the cultivated medium by fixed-bed and simulated moving bed （SMB） chromatography. The separation conditions including pH, eluent concentration and Lys+ and Lys2+ adsorption isotherms were studied in batch adsorption. The column capacity, eluent flow rate and eluent concentration have been studied in fixed-bed chromatography. Maximum purification rate of lysine was obtained as 0.066 （g/（g·h）） （per gram resin and per hour） at an eluent flow rate of 10 （mL/min） in fixed-bed chromatography. The results obtained from SMB were 0.11 （g/（g·h）） for L-lysine purification rate and 96% for L-lysine recovery.展开更多
聚醚醚酮(polyetheretherketone,PEEK)材料作为典型的轻质高性能聚合物材料,在医疗航空航天等领域获得了大量应用,PEEK材料的增材制造技术可以实现复杂零部件的结构功能一体化制造。针对聚醚醚酮粉末床熔融(powder bed fusion,PBF)系统...聚醚醚酮(polyetheretherketone,PEEK)材料作为典型的轻质高性能聚合物材料,在医疗航空航天等领域获得了大量应用,PEEK材料的增材制造技术可以实现复杂零部件的结构功能一体化制造。针对聚醚醚酮粉末床熔融(powder bed fusion,PBF)系统加工温度高、易翘曲的难题,开展了聚醚醚酮粉末床熔融系统多工艺参数优化与成形性能研究,通过工艺成形过程模拟仿真,揭示了激光功率等核心参数对温度场的影响规律。在成形工艺仿真基础上,开展了成形工艺参数优化试验,建立了工艺参数与拉伸力学性能以及翘曲率的对应关系,获得了拉伸强度86 MPa,断裂伸长率3.7%的优异力学性能,并最终实现了颅骨植入物的高精度增材制造。展开更多
文摘L-Lysine was produced by a microbial process utilizing a Corynebacterium glutamicum （ATCC 21799） strain. L-Lysine was purified from the cultivated medium by fixed-bed and simulated moving bed （SMB） chromatography. The separation conditions including pH, eluent concentration and Lys+ and Lys2+ adsorption isotherms were studied in batch adsorption. The column capacity, eluent flow rate and eluent concentration have been studied in fixed-bed chromatography. Maximum purification rate of lysine was obtained as 0.066 （g/（g·h）） （per gram resin and per hour） at an eluent flow rate of 10 （mL/min） in fixed-bed chromatography. The results obtained from SMB were 0.11 （g/（g·h）） for L-lysine purification rate and 96% for L-lysine recovery.
文摘聚醚醚酮(polyetheretherketone,PEEK)材料作为典型的轻质高性能聚合物材料,在医疗航空航天等领域获得了大量应用,PEEK材料的增材制造技术可以实现复杂零部件的结构功能一体化制造。针对聚醚醚酮粉末床熔融(powder bed fusion,PBF)系统加工温度高、易翘曲的难题,开展了聚醚醚酮粉末床熔融系统多工艺参数优化与成形性能研究,通过工艺成形过程模拟仿真,揭示了激光功率等核心参数对温度场的影响规律。在成形工艺仿真基础上,开展了成形工艺参数优化试验,建立了工艺参数与拉伸力学性能以及翘曲率的对应关系,获得了拉伸强度86 MPa,断裂伸长率3.7%的优异力学性能,并最终实现了颅骨植入物的高精度增材制造。
