Objective To explore the contrast-enhanced ultrasonographic features for quantitative assessment of hepatic fibrosis. Methods 86 patients with chronic viral hepatitis B were enrolled in this study from March 2007 to A...Objective To explore the contrast-enhanced ultrasonographic features for quantitative assessment of hepatic fibrosis. Methods 86 patients with chronic viral hepatitis B were enrolled in this study from March 2007 to August 2009. The patients were classified into 5 groups (S0-S4) according to fibrosis stage evaluated with ultrasound guided liver biopsy. New contrast-enhanced ultrasonography (CEUS) features including area under the time-intensity curve (TIC) of portal venous phase/hepatic arterial phase (Qp/Qa) and intensity of portal venous phase/hepatic arterial phase (Ip/Ia) were used to detect the blood supply ratio (portal vein/hepatic artery) in each group. Arrival time of portal vein trunk (Tp) and decreasing rate of TIC (β ) were also analyzed. Results Qp/Qa and Ip/Ia decreased from S0 to S4, while Tp and β increased. These 4 features were significantly correlated with the degree of fibrosis (P<0.001) and were significantly different among the five groups (P<0.001). Sensitivity and specificity of Ip/Ia were 80% and 86% for groups ≥S1, 75% and 86% for groups ≥ S2, 71% and 84% for groups ≥ S3, and 76% and 80% for group S4, respectively. Sensitivity and specificity of Qp/Qa were 70% and 88% for groups ≥ S1, 80% and 76% for groups ≥ S2, 74% and 70% for groups ≥ S3, and 81% and 95% for group S4, respectively. Conclusion Ip/Ia and Qp/Qa could be adopted as reliable, non-invasive features for quantitative assessment of hepatic fibrosis.展开更多
The development and application of the ''digital mine'' concept in China depends heavily upon the use of remote sensing data as well as domestic expertise and awareness. Illegal mining of mineral resou...The development and application of the ''digital mine'' concept in China depends heavily upon the use of remote sensing data as well as domestic expertise and awareness. Illegal mining of mineral resources has been a serious long term problem frustrating the Xishimen Iron Ore Mine management. This mine is located in Wu'an county in Hebei province, China. Illegal activities have led to enormous economic losses by interfering with the normal operation of the Xishimen mine and have ruined the surrounding environ- ment and the stability of the Mahe riverbed the crosses the mined area. This paper is based on field recon- naissance taken over many years around the mine area. The ground survey data are integrated with Differential Synthetic Aperture Radar Interferometry (D-InSAR) results from ALOS/PALSAR data to pin- point mining locations. By investigating the relationship between the resulting interferometric deforma- tion pattern and the mining schedule, which is known a priori, areas affected by illegal mining activities are identified. To some extent these areas indicate the location of the illegal site. The results clearly dem- onstrate D-InSAR's ability to cost-effectively monitor illegal mining activities.展开更多
基金Supported by PhD Programs Foundation of Ministry of Education of China (No. 20090001110092)
文摘Objective To explore the contrast-enhanced ultrasonographic features for quantitative assessment of hepatic fibrosis. Methods 86 patients with chronic viral hepatitis B were enrolled in this study from March 2007 to August 2009. The patients were classified into 5 groups (S0-S4) according to fibrosis stage evaluated with ultrasound guided liver biopsy. New contrast-enhanced ultrasonography (CEUS) features including area under the time-intensity curve (TIC) of portal venous phase/hepatic arterial phase (Qp/Qa) and intensity of portal venous phase/hepatic arterial phase (Ip/Ia) were used to detect the blood supply ratio (portal vein/hepatic artery) in each group. Arrival time of portal vein trunk (Tp) and decreasing rate of TIC (β ) were also analyzed. Results Qp/Qa and Ip/Ia decreased from S0 to S4, while Tp and β increased. These 4 features were significantly correlated with the degree of fibrosis (P<0.001) and were significantly different among the five groups (P<0.001). Sensitivity and specificity of Ip/Ia were 80% and 86% for groups ≥S1, 75% and 86% for groups ≥ S2, 71% and 84% for groups ≥ S3, and 76% and 80% for group S4, respectively. Sensitivity and specificity of Qp/Qa were 70% and 88% for groups ≥ S1, 80% and 76% for groups ≥ S2, 74% and 70% for groups ≥ S3, and 81% and 95% for group S4, respectively. Conclusion Ip/Ia and Qp/Qa could be adopted as reliable, non-invasive features for quantitative assessment of hepatic fibrosis.
基金supported by the National Hi-Tech Research and Development Program of China (No. 2009AA11Z105)the sponsors of Hanxing Iron Ore Mine Administration Bureau for providing the research funds,insitu test assistance and monitor work
文摘The development and application of the ''digital mine'' concept in China depends heavily upon the use of remote sensing data as well as domestic expertise and awareness. Illegal mining of mineral resources has been a serious long term problem frustrating the Xishimen Iron Ore Mine management. This mine is located in Wu'an county in Hebei province, China. Illegal activities have led to enormous economic losses by interfering with the normal operation of the Xishimen mine and have ruined the surrounding environ- ment and the stability of the Mahe riverbed the crosses the mined area. This paper is based on field recon- naissance taken over many years around the mine area. The ground survey data are integrated with Differential Synthetic Aperture Radar Interferometry (D-InSAR) results from ALOS/PALSAR data to pin- point mining locations. By investigating the relationship between the resulting interferometric deforma- tion pattern and the mining schedule, which is known a priori, areas affected by illegal mining activities are identified. To some extent these areas indicate the location of the illegal site. The results clearly dem- onstrate D-InSAR's ability to cost-effectively monitor illegal mining activities.
