GA-GP is an algorithm for dealing with all kinds of nonlinear function relationships and fraction relationships, which use GP(Genetic programming) to create new individuals and GA(Genetic algorithm)to optimize them at...GA-GP is an algorithm for dealing with all kinds of nonlinear function relationships and fraction relationships, which use GP(Genetic programming) to create new individuals and GA(Genetic algorithm)to optimize them at the same time. In this way we make full advantage of GA and GP. We discuss the application of this algorithm in quantitative structure-activity relationships(QSAR) in the medicinal field. The result shows that GA-GP is better than ANN and mathematical expressions could be obtained. Expressions clearly express and explain QSAR of the medicine. All can show GA-GP has very wide applications in the medicinal field of the molecule design.展开更多
文摘GA-GP is an algorithm for dealing with all kinds of nonlinear function relationships and fraction relationships, which use GP(Genetic programming) to create new individuals and GA(Genetic algorithm)to optimize them at the same time. In this way we make full advantage of GA and GP. We discuss the application of this algorithm in quantitative structure-activity relationships(QSAR) in the medicinal field. The result shows that GA-GP is better than ANN and mathematical expressions could be obtained. Expressions clearly express and explain QSAR of the medicine. All can show GA-GP has very wide applications in the medicinal field of the molecule design.
