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癫痫动物模型的研究进展 被引量:5
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作者 董博思 邱湘苗 +3 位作者 赖婉琳 李宛凌 彭安娇 陈蕾 《中国比较医学杂志》 CAS 北大核心 2021年第3期128-138,共11页
癫痫是一种常见的神经疾病,但我们对于其病因知之甚少,因此很难找到有效的治疗方法。在过去的30年里,癫痫动物模型在研究癫痫发生机制和确定潜在治疗药物等方面都起着至关重要的作用。但迄今为止,还没有任何一个理想的单一模型被证实可... 癫痫是一种常见的神经疾病,但我们对于其病因知之甚少,因此很难找到有效的治疗方法。在过去的30年里,癫痫动物模型在研究癫痫发生机制和确定潜在治疗药物等方面都起着至关重要的作用。但迄今为止,还没有任何一个理想的单一模型被证实可用于识别潜在的药物和充分解释癫痫的发生原因。本综述对目前制备癫痫动物模型的方法及优化方案进行总结,为癫痫模型的选择提供参考,并提供了未来一些癫痫模型制备方向的见解。 展开更多
关键词 癫痫 动物模型 点燃模型 遗传性模型
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Job shop scheduling problem with alternative machines using genetic algorithms 被引量:10
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作者 I.A.Chaudhry 《Journal of Central South University》 SCIE EI CAS 2012年第5期1322-1333,共12页
The classical job shop scheduling problem(JSP) is the most popular machine scheduling model in practice and is known as NP-hard.The formulation of the JSP is based on the assumption that for each part type or job ther... The classical job shop scheduling problem(JSP) is the most popular machine scheduling model in practice and is known as NP-hard.The formulation of the JSP is based on the assumption that for each part type or job there is only one process plan that prescribes the sequence of operations and the machine on which each operation has to be performed.However,JSP with alternative machines for various operations is an extension of the classical JSP,which allows an operation to be processed by any machine from a given set of machines.Since this problem requires an additional decision of machine allocation during scheduling,it is much more complex than JSP.We present a domain independent genetic algorithm(GA) approach for the job shop scheduling problem with alternative machines.The GA is implemented in a spreadsheet environment.The performance of the proposed GA is analyzed by comparing with various problem instances taken from the literatures.The result shows that the proposed GA is competitive with the existing approaches.A simplified approach that would be beneficial to both practitioners and researchers is presented for solving scheduling problems with alternative machines. 展开更多
关键词 alternative machine genetic algorithm (GA) job shop scheduling SPREADSHEET
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Nonlinear correction of photoelectric displacement sensor based on least square support vector machine 被引量:1
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作者 郭杰荣 何怡刚 刘长青 《Journal of Central South University》 SCIE EI CAS 2011年第5期1614-1618,共5页
A model of correcting the nonlinear error of photoelectric displacement sensor was established based on the least square support vector machine.The parameters of the correcting nonlinear model,such as penalty factor a... A model of correcting the nonlinear error of photoelectric displacement sensor was established based on the least square support vector machine.The parameters of the correcting nonlinear model,such as penalty factor and kernel parameter,were optimized by chaos genetic algorithm.And the nonlinear correction of photoelectric displacement sensor based on least square support vector machine was applied.The application results reveal that error of photoelectric displacement sensor is less than 1.5%,which is rather satisfactory for nonlinear correction of photoelectric displacement sensor. 展开更多
关键词 least square support vector machine POSITION photoelectric displacement sensor nonlinear correct
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