Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular commun...Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular communication in the cultured bladder detrusor cells was detected by fluorescence redistribution after photobleaching. Results: At the fourth minute after bleaching, the mean fluorescences recovery rates of DI group bladder detrusor cells were (35 791±0 836)%, that of control group (8 645±0 673)%. The mean fluorescence recovery rates of DI group were significantly higher than those of control group ( P <0 01). Conclusion: It shows that the increase of intercellular excitatory communication is one of the important reasons of pathogenesis of DI.展开更多
Transmission Control Protocol （TCP） in infrastructure based vehicular net- works is dedicated to support reliable Intemet services for mobile users. However, an end-to- end TCP flow not only experiences some com- mo...Transmission Control Protocol （TCP） in infrastructure based vehicular net- works is dedicated to support reliable Intemet services for mobile users. However, an end-to- end TCP flow not only experiences some com- mon challenges in wireless mobile networks, such as high packet loss rate, medium access competition, unstable wireless bandwidth, and dynamic topology, etc., but also suffers from performance degradation due to traffic congestion at the Road-Side Units （RSUs） that connect the wireline and wireless networks. In order to address the challenging issues related to reliable TCP transmissions in infrastruc- ture based vehicular networks, we propose an RSU based TCP （R-TCP） scheme. For wireline source nodes, R-TCP adopts a novel flow control mechanism to adjust transmission rates according to the status of bottleneck link. Specifically, during the short wireless connec- tion time in Infrastructure based vehicular net- works, R-TCP quickly chooses an ideal trans- mission rate for data transmissions instead of activating the slow start algorithm after the connection is established, and successfully avoids the oscillation of the transmission rate. Simulation results show that R-TCP achieves great advantages than some relate proposals in terms of throughput, end-to-end delay, and packet loss rate.展开更多
文摘Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular communication in the cultured bladder detrusor cells was detected by fluorescence redistribution after photobleaching. Results: At the fourth minute after bleaching, the mean fluorescences recovery rates of DI group bladder detrusor cells were (35 791±0 836)%, that of control group (8 645±0 673)%. The mean fluorescence recovery rates of DI group were significantly higher than those of control group ( P <0 01). Conclusion: It shows that the increase of intercellular excitatory communication is one of the important reasons of pathogenesis of DI.
基金supported in part by Fundamental Research Funds for the Central Universities of China under Grant(N140405004) partly by National Natural Science Foundation of China(61373159)+1 种基金partly by Educational Committee of Liaoning Province science and technology research projects under Grant (L2013096)partly by Key Laboratory Project Funds of Shenyang Ligong University (4771004kfs03)
文摘Transmission Control Protocol （TCP） in infrastructure based vehicular net- works is dedicated to support reliable Intemet services for mobile users. However, an end-to- end TCP flow not only experiences some com- mon challenges in wireless mobile networks, such as high packet loss rate, medium access competition, unstable wireless bandwidth, and dynamic topology, etc., but also suffers from performance degradation due to traffic congestion at the Road-Side Units （RSUs） that connect the wireline and wireless networks. In order to address the challenging issues related to reliable TCP transmissions in infrastruc- ture based vehicular networks, we propose an RSU based TCP （R-TCP） scheme. For wireline source nodes, R-TCP adopts a novel flow control mechanism to adjust transmission rates according to the status of bottleneck link. Specifically, during the short wireless connec- tion time in Infrastructure based vehicular net- works, R-TCP quickly chooses an ideal trans- mission rate for data transmissions instead of activating the slow start algorithm after the connection is established, and successfully avoids the oscillation of the transmission rate. Simulation results show that R-TCP achieves great advantages than some relate proposals in terms of throughput, end-to-end delay, and packet loss rate.
