目的探讨脑小血管病患者步态及平衡障碍的特征。方法连续纳入2013年6月至2015年2月就诊于北京协和医院神经内科门诊的脑小血管病患者57例,收集临床资料,对其日常生活能力、整体运动功能及步态和平衡功能进行评价。结果 57例患者中,男性7...目的探讨脑小血管病患者步态及平衡障碍的特征。方法连续纳入2013年6月至2015年2月就诊于北京协和医院神经内科门诊的脑小血管病患者57例,收集临床资料,对其日常生活能力、整体运动功能及步态和平衡功能进行评价。结果 57例患者中,男性71.9%,年龄(64.5±12.4)岁;45.6%(26/57)以步态障碍为主诉,73.7%(42/57)Barthel指数≥90分。帕金森病统一评分量表(Unified Parkinson’s Disease Rating Scale,UPDRS)评分(14.2±10.1)分,共济失调等级量表(Scale for the Assessment and Rating of Ataxia,SARA)(5.2±3.6)分;70.2%(40/57)Tinetti步态评分<12分,易累及的步态特征是步高、步宽(基)、步长对称性;50.9%(29/57)Tinetti平衡评分<16分,易受累的平衡特征是360°转身、轻推试验、座位起立;简明运动试验(Short Physical Performance Battery,SPPB)中,3米步行所需时间是(5.0±1.9)s,其中72.7%(24/33)步行时间≥3.62 s(评分≤3分)。结论半数以上患者表现出步态障碍,但对整体运动功能和日常生活能力影响较小;步态障碍主要表现为速度减慢、拖地、步基宽和双侧步长不等。步态和平衡功能障碍的早期评价对于预防跌倒和生活能力下降有重要意义。展开更多
A simulation-based multi-objective optimization approach for roll shifting strategy in hot strip mills was presented. Firstly, the effect of roll shifting strategy on wear contour was investigated by mtmerical simulat...A simulation-based multi-objective optimization approach for roll shifting strategy in hot strip mills was presented. Firstly, the effect of roll shifting strategy on wear contour was investigated by mtmerical simulation, and two evaluation indexes including edge smoothness and body smoothness of wear contours were introduced. Secondly, the edge smoothness average and body smoothness average of all the strips in a rolling campaign were selected as objective functions, and shifting control parameters as decision variables, the multi-objective method of MODE/D as the optimizer, and then a simulation-based multi-objective optimization model for roll shifting strategy was built. The experimental result shows that MODE/D can obtain a good Pareto-optimal front, which suggests a series of alternative solutions to roll shifting strategy. Moreover, the conflicting relationship between two objectives can also be found, which indicates another advantage of multi-objective optimization. Finally, industrial test confirms the feasibility of the multi-objective approach for roll shifting strategy, and it can improve strip profile and extend same width rolling miles of a rolling campaign from 35 km to 70 km.展开更多
文摘目的探讨脑小血管病患者步态及平衡障碍的特征。方法连续纳入2013年6月至2015年2月就诊于北京协和医院神经内科门诊的脑小血管病患者57例,收集临床资料,对其日常生活能力、整体运动功能及步态和平衡功能进行评价。结果 57例患者中,男性71.9%,年龄(64.5±12.4)岁;45.6%(26/57)以步态障碍为主诉,73.7%(42/57)Barthel指数≥90分。帕金森病统一评分量表(Unified Parkinson’s Disease Rating Scale,UPDRS)评分(14.2±10.1)分,共济失调等级量表(Scale for the Assessment and Rating of Ataxia,SARA)(5.2±3.6)分;70.2%(40/57)Tinetti步态评分<12分,易累及的步态特征是步高、步宽(基)、步长对称性;50.9%(29/57)Tinetti平衡评分<16分,易受累的平衡特征是360°转身、轻推试验、座位起立;简明运动试验(Short Physical Performance Battery,SPPB)中,3米步行所需时间是(5.0±1.9)s,其中72.7%(24/33)步行时间≥3.62 s(评分≤3分)。结论半数以上患者表现出步态障碍,但对整体运动功能和日常生活能力影响较小;步态障碍主要表现为速度减慢、拖地、步基宽和双侧步长不等。步态和平衡功能障碍的早期评价对于预防跌倒和生活能力下降有重要意义。
基金Projects(50974039,50634030) supported by the National Natural Science Foundation of China
文摘A simulation-based multi-objective optimization approach for roll shifting strategy in hot strip mills was presented. Firstly, the effect of roll shifting strategy on wear contour was investigated by mtmerical simulation, and two evaluation indexes including edge smoothness and body smoothness of wear contours were introduced. Secondly, the edge smoothness average and body smoothness average of all the strips in a rolling campaign were selected as objective functions, and shifting control parameters as decision variables, the multi-objective method of MODE/D as the optimizer, and then a simulation-based multi-objective optimization model for roll shifting strategy was built. The experimental result shows that MODE/D can obtain a good Pareto-optimal front, which suggests a series of alternative solutions to roll shifting strategy. Moreover, the conflicting relationship between two objectives can also be found, which indicates another advantage of multi-objective optimization. Finally, industrial test confirms the feasibility of the multi-objective approach for roll shifting strategy, and it can improve strip profile and extend same width rolling miles of a rolling campaign from 35 km to 70 km.
