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抗精神病药物所致的代谢综合征中医证型分布规律研究
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作者 冼淑连 贾竑晓 +4 位作者 李雪 王娣 宋明康 尹冬青 姜海荣 《首都医科大学学报》 北大核心 2025年第3期463-470,共8页
目的探索抗精神病药物所致的代谢综合征的中医证型分布规律。方法使用标准化的中医证候调查表,采集160例符合诊断标准的抗精神病药物所致的代谢综合征患者的四诊信息,并进行频率分析、聚类分析、贝叶斯网络分析,结合文献资料、专家意见... 目的探索抗精神病药物所致的代谢综合征的中医证型分布规律。方法使用标准化的中医证候调查表,采集160例符合诊断标准的抗精神病药物所致的代谢综合征患者的四诊信息,并进行频率分析、聚类分析、贝叶斯网络分析,结合文献资料、专家意见判定证型分布。结果通过频率分析、聚类分析以及贝叶斯网络分析,判断出了5个中医证型,其中气虚痰湿证占比最高(30%),其次为脾虚痰热证(23.75%)、气阴两虚证(21.88%)、阴虚湿热证(17.50%)、胃热炽盛证(6.88%)。结论抗精神病药物所致的代谢综合征的病机虚实夹杂,病位主要在脾胃,涉及肝、肾、心。病性有气虚、阴虚、湿、热、火、痰等。 展开更多
关键词 抗精神病药物 代谢综合征 中医证型 聚类分析 贝叶斯网络分析
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Handling epistemic uncertainties in PRA using evidential networks
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作者 王冬 陈进 +1 位作者 程志君 郭波 《Journal of Central South University》 SCIE EI CAS 2014年第11期4261-4269,共9页
In order to overcome the limitations of traditional methods in uncertainty analysis, a modified Bayesian network(BN), which is called evidence network(EN), was proposed with evidence theory to handle epistemic uncerta... In order to overcome the limitations of traditional methods in uncertainty analysis, a modified Bayesian network(BN), which is called evidence network(EN), was proposed with evidence theory to handle epistemic uncertainty in probabilistic risk assessment(PRA). Fault trees(FTs) and event trees(ETs) were transformed into an EN which is used as a uniform framework to represent accident scenarios. Epistemic uncertainties of basic events in PRA were presented in evidence theory form and propagated through the network. A case study of a highway tunnel risk analysis was discussed to demonstrate the proposed approach. Frequencies of end states are obtained and expressed by belief and plausibility measures. The proposed approach addresses the uncertainties in experts' knowledge and can be easily applied to uncertainty analysis of FTs/ETs that have dependent events. 展开更多
关键词 probabilistic risk assessment epistemic uncertainty evidence theory evidential network
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