Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to Ja...Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.展开更多
The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures hav...The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.展开更多
When detecting deletions in complex human genomes,split-read approaches using short reads generated with next-generation sequencing still face the challenge that either false discovery rate is high,or sensitivity is l...When detecting deletions in complex human genomes,split-read approaches using short reads generated with next-generation sequencing still face the challenge that either false discovery rate is high,or sensitivity is low.To address the problem,an integrated strategy is proposed.It organically combines the fundamental theories of the three mainstream methods(read-pair approaches,split-read technologies and read-depth analysis) with modern machine learning algorithms,using the recipe of feature extraction as a bridge.Compared with the state-of-art split-read methods for deletion detection in both low and high sequence coverage,the machine-learning-aided strategy shows great ability in intelligently balancing sensitivity and false discovery rate and getting a both more sensitive and more precise call set at single-base-pair resolution.Thus,users do not need to rely on former experience to make an unnecessary trade-off beforehand and adjust parameters over and over again any more.It should be noted that modern machine learning models can play an important role in the field of structural variation prediction.展开更多
基金Project(CSTC 2004AA7008) supported by the State I mportant Project of the Science and Technology
文摘Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.
文摘The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.
基金Project(61472026)supported by the National Natural Science Foundation of ChinaProject(2014J410081)supported by Guangzhou Scientific Research Program,China
文摘When detecting deletions in complex human genomes,split-read approaches using short reads generated with next-generation sequencing still face the challenge that either false discovery rate is high,or sensitivity is low.To address the problem,an integrated strategy is proposed.It organically combines the fundamental theories of the three mainstream methods(read-pair approaches,split-read technologies and read-depth analysis) with modern machine learning algorithms,using the recipe of feature extraction as a bridge.Compared with the state-of-art split-read methods for deletion detection in both low and high sequence coverage,the machine-learning-aided strategy shows great ability in intelligently balancing sensitivity and false discovery rate and getting a both more sensitive and more precise call set at single-base-pair resolution.Thus,users do not need to rely on former experience to make an unnecessary trade-off beforehand and adjust parameters over and over again any more.It should be noted that modern machine learning models can play an important role in the field of structural variation prediction.
