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电针配合加味补阳还五汤对血管性痴呆患者记忆行为学、血清BDNF、VEGF及神经元凋亡相关分子表达的影响 被引量:18
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作者 王洋岗 周春燕 +2 位作者 任惠明 张晋 郭旭 《中华中医药学刊》 CAS 北大核心 2022年第5期81-84,268,共5页
目的探讨电针配合加味补阳还五汤对血管性痴呆(vascular dementia,VD)患者记忆行为学、血清脑源性神经营养因子(BDNF)、血管内皮生长因子(VEGF)及神经元凋亡相关分子表达的影响。方法选取2018年6月—2020年5月医院106例VD患者作为研究对... 目的探讨电针配合加味补阳还五汤对血管性痴呆(vascular dementia,VD)患者记忆行为学、血清脑源性神经营养因子(BDNF)、血管内皮生长因子(VEGF)及神经元凋亡相关分子表达的影响。方法选取2018年6月—2020年5月医院106例VD患者作为研究对象,简单随机化分组,各53例。对照组予以电针治疗,观察组予以电针联合加味补阳还五汤治疗,连续治疗3个月。观察对比两组临床疗效、治疗前后中医证候积分、大脑中动脉血流速度、认知功能(MMSE)、记忆(WMS)、行为(BBS)评分、血清BDNF、VEGF及神经元凋亡相关因子B细胞淋巴瘤-2(Bcl-2)、Bcl-2相关X蛋白(Bax)、半胱氨酸蛋白酶(Caspase)-3表达。结果观察组治疗总有效率高于对照组(P<0.05);观察组治疗1个月、3个月后中医证候积分、BBS评分低于对照组,MMSE、WMS评分高于对照组(P<0.05);观察组治疗1个月、3个月后Bcl-2、BDNF、VEGF高于对照组,Bax、Caspase-3低于对照组(P<0.05);观察组治疗1个月、3个月后大脑中动脉血流速度高于对照组(P<0.05)。结论电针配合加味补阳还五汤治疗VD患者,可明显改善患者症状,增加大脑中动脉血流速度,可升高BDNF、VEGF水平,调节神经元凋亡相关因子水平,进一步提高治疗效果,在临床治疗中具有重要意义。 展开更多
关键词 血管性痴呆 电针 补阳还五汤 记忆行为学 BDNF VEGF 神经元凋亡相关分子
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Optical memory behavior of MoS_(2) nanoflakes doped liquid crystals hybrid
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作者 GONG Xiaohui ZHANG Hao +1 位作者 YANG Dongfang LIU Yang 《液晶与显示》 北大核心 2025年第5期665-673,共9页
The memory behavior in liquid crystals(LCs)that is characterized by low cost,large area,high speed,and high-density memory has evolved from a mere scientific curiosity to a technology that is being applied in a variet... The memory behavior in liquid crystals(LCs)that is characterized by low cost,large area,high speed,and high-density memory has evolved from a mere scientific curiosity to a technology that is being applied in a variety of commodities.In this study,we utilized molybdenum disulfide(MoS_(2))nanoflakes as the guest in a homotropic LCs host to modulate the overall memory effect of the hybrid.It was found that the MoS₂nanoflakes within the LCs host formed agglomerates,which in turn resulted in an accelerated response of the hybrids to the external electric field.However,this process also resulted in a slight decrease in the threshold voltage.Additionally,it was observed that MoS₂nanoflakes in a LCs host tend to align homeotropically under an external electric field,thereby accelerating the refreshment of the memory behavior.The incorporation of a mass fraction of 0.1%2μm MoS₂nanoflakes into the LCs host was found to significantly reduce the refreshing memory behavior in the hybrid to 94.0 s under an external voltage of 5 V.These findings illustrate the efficacy of regulating the rate of memory behavior for a variety of potential applications. 展开更多
关键词 optical memory behavior MoS_(2)nanoflake liquid crystal
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