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基于三维打印的钙化层重建生物活性支架制备及其性能研究
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作者 余新宁 方晶华 +4 位作者 骆建洋 杨贤燕 何冬霜 苟中入 戴雪松 《浙江大学学报(医学版)》 CAS CSCD 北大核心 2016年第2期126-131,共6页
目的:初步构建基于软骨钙化层损伤重建的有机—无机复合组织工程支架,探究掺镁硅灰石含量与支架抗压性能之间的关系。方法:利用质量分数分别为1%、3%、5%的高生物活性钙镁硅酸盐超细颗粒复合Ⅰ型胶原-透明质酸钠进行三维打印,经... 目的:初步构建基于软骨钙化层损伤重建的有机—无机复合组织工程支架,探究掺镁硅灰石含量与支架抗压性能之间的关系。方法:利用质量分数分别为1%、3%、5%的高生物活性钙镁硅酸盐超细颗粒复合Ⅰ型胶原-透明质酸钠进行三维打印,经海藻酸钠-氯化钙气雾交联成型,电镜下观察表面孔隙、孔径、无机相分布,万能材料试验机测试抗压性能,并计算支架孔隙率。结果:支架表面平均孔径(212.3±34.2)μm,平均孔隙率(48.3±5.9)%,不同质量分数的高生物活性钙镁硅酸盐超细颗粒复合Ⅰ型胶原-透明质酸钠支架压缩模量差异无统计学意义(P〉0.05),平均压缩模量(7.2±1.2)MPa,介于软骨和软骨下骨之间。结论:利用三维打印技术成功构建出多孔钙化层仿生重建支架,可为今后研制多层次复合支架治疗骨-软骨损伤奠定基础。 展开更多
关键词 软骨疾病/治疗 钙化合物 透明质酸 胶原Ⅰ型 计算机辅助设 成像 三维 海藻酸钠 支架
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Evaluation of working fluids for organic Rankine cycles using group-contribution methods and second-law-based models 被引量:1
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作者 MA Wei-wu WANG Lin +1 位作者 LIU Tao LI Min 《Journal of Central South University》 SCIE EI CAS CSCD 2019年第8期2234-2243,共10页
The group-contribution (GC) methods suffer from a limitation concerning to the prediction of process-related indexes, e.g., thermal efficiency. Recently developed analytical models for thermal efficiency of organic Ra... The group-contribution (GC) methods suffer from a limitation concerning to the prediction of process-related indexes, e.g., thermal efficiency. Recently developed analytical models for thermal efficiency of organic Rankine cycles (ORCs) provide a possibility of overcoming the limitation of the GC methods because these models formulate thermal efficiency as functions of key thermal properties. Using these analytical relations together with GC methods, more than 60 organic fluids are screened for medium-low temperature ORCs. The results indicate that the GC methods can estimate thermal properties with acceptable accuracy (mean relative errors are 4.45%-11.50%);the precision, however, is low because the relative errors can vary from less than 0.1% to 45.0%. By contrast, the GC-based estimation of thermal efficiency has better accuracy and precision. The relative errors in thermal efficiency have an arithmetic mean of about 2.9% and fall within the range of 0-24.0%. These findings suggest that the analytical equations provide not only a direct way of estimating thermal efficiency but an accurate and precise approach to evaluating working fluids and guiding computer-aided molecular design of new fluids for ORCs using GC methods. 展开更多
关键词 organic Rankine cycles (ORCs) group contribution methods working fluids property estimation computer-aided molecular design
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Synthesis of fractal geometry and CAGD models for multi-scale topography modelling of functional surfaces 被引量:3
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作者 王清辉 李静蓉 +2 位作者 陈彦政 潘敏强 汤勇 《Journal of Central South University》 SCIE EI CAS 2011年第5期1493-1501,共9页
In order to support the functional design and simulation and the final fabrication processes for functional surfaces,it is necessary to obtain a multi-scale modelling approach representing both macro geometry and micr... In order to support the functional design and simulation and the final fabrication processes for functional surfaces,it is necessary to obtain a multi-scale modelling approach representing both macro geometry and micro details of the surface in one unified model.Based on the fractal geometry theory,a synthesized model is proposed by mathematically combining Weierstrass-Mandelbrot fractal function in micro space and freeform CAGD model in macro space.Key issues of the synthesis,such as algorithms for fractal interpolation of freeform profiles,and visualization optimization for fractal details,are addressed.A prototype of the integration solution is developed based on the platform of AutoCAD's Object ARX,and a few multi-scale modelling examples are used as case studies.With the consistent mathematic model,multi-scale surface geometries can be represented precisely.Moreover,the visualization result of the functional surfaces shows that the visualization optimization strategies developed are efficient. 展开更多
关键词 surface roughness MICROTOPOGRAPHY fractal geometry functional surface
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Modeling,fabrication and measurement of a novel CMOS UV/blue-extended photodiode
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作者 陈长平 赵永嘉 +3 位作者 周晓亚 金湘亮 杨红姣 罗均 《Journal of Central South University》 SCIE EI CAS 2014年第10期3821-3827,共7页
A new complementary metal oxide semiconductor UV/blue-extended photodiode was presented for light detection in the UV/blue spectral range. Photoelectric characteristics of this presented photodiode were studied by num... A new complementary metal oxide semiconductor UV/blue-extended photodiode was presented for light detection in the UV/blue spectral range. Photoelectric characteristics of this presented photodiode were studied by numerical modeling and device simulation. Technology computer aided design simulation was done first to analyze its photoelectric characteristics. The structure characteristic and depletion situation of space between two adjacent P+ anodes were discussed. The reverse characteristic, spectral response characteristic and DC characteristic were discussed in detail. For the numerical modeling, dead layer effect is considered in the building of analytical mode. Dead layer is a space in which the boron doping profile decreases towards the surface due to high doping effects and boron redistribution, which affects the sensitivity of photodiode in the UV range seriously. Reverse characteristics and spectral response characteristics were modeled and analyzed typically. At last, silicon test results were given and compared with the simulated result, which shows reasonable match for each. 展开更多
关键词 device simulation numerical modeling ultraviolet responsivity photoelectric characteristics avalanche breakdown voltage silicon
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Scheme optimization of AT shifting element based on genetic algorithm
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作者 岳会军 刘艳芳 +2 位作者 马明月 徐向阳 王书翰 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第2期539-545,共7页
In order to realize the computer aided design of AT shifting element schemes, a mathematical model of shifting element schemes which can be easily identified by computers was built. Taking the transmission ratio seque... In order to realize the computer aided design of AT shifting element schemes, a mathematical model of shifting element schemes which can be easily identified by computers was built. Taking the transmission ratio sequence as an optimization objective and simple shifting logic between adjacent gears through operating only one shifting element as a constraint condition, a fitness function of shifting element schemes was proposed. ZF-8AT shifting element schemes were optimized based on GA work-box of MATLAB, and the feasibility of the optimization algorithm was verified. 展开更多
关键词 hydrodynamic automatic transmission shifting element scheme optimization
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