Artificial bone with porous structure is crucial for tissue scaffold and clinic implants.Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure.A computational aided p...Artificial bone with porous structure is crucial for tissue scaffold and clinic implants.Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure.A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture,porosity and pore size.To simulate intricate bone structure,different constructive units were presented.In modeling process,bone contour was gotten from computed tomography(CT)images and was divided into two levels.Each level was represented by relatively reconstructive process.Pore size distribution was controlled by using mesh generation.The whole hexahedral mesh was reduced by unit structure,when a 3D mesh with various hexahedral elements was provided.The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.展开更多
Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component p...Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component phases of the cement paste such as pores, hydration products, and unhydrated clinker particles were segmented from each other based on their 3D image grey levels; their relative contents were also calculated with the software, and the data are 61.2%, 0% and 38.8% at the beginning of hydration and 11.8%, 78.5% and 9.7% at 28 d age, respectively. The hydration degree of cement paste at different ages was compared with the experimental data acquired by loss on ignition (LOI) tests. The results show that the calculated and measured data reasonably agree with each other, which indicates that micro-CT is a useful and reliable approach to characterize the micro structure evolution of hydrating cement paste.展开更多
基金Project(2011DFB70230)supported by State International Cooperation Program of ChinaProject(N110403003)supported by Basic Research Foundation of Education Ministry of China
文摘Artificial bone with porous structure is crucial for tissue scaffold and clinic implants.Scaffold provides structure support for cells and guides tissues regeneration for final tissue structure.A computational aided process of porous bone modeling was developed which described the design and fabrication of tissue scaffolds by considering intricate architecture,porosity and pore size.To simulate intricate bone structure,different constructive units were presented.In modeling process,bone contour was gotten from computed tomography(CT)images and was divided into two levels.Each level was represented by relatively reconstructive process.Pore size distribution was controlled by using mesh generation.The whole hexahedral mesh was reduced by unit structure,when a 3D mesh with various hexahedral elements was provided.The simulation results show that constructive structure of porous scaffold can meet the needs of clinic implants in accurate and controlled way.
基金Project(2009CB623201) supported by the National Basic Research Program of ChinaProjects(50902106, 51272193) supported by the National Natural Science Foundation of ChinaProject(NCET-10-0660) supported by New Century Excellent Talents in Universities of China
文摘Micro computed tomography (Micro-CT) was applied to obtain three-dimensional images of the microstructure of cement paste (water-to-cement mass ratio of 0.5) at different ages. By using the Amira software, component phases of the cement paste such as pores, hydration products, and unhydrated clinker particles were segmented from each other based on their 3D image grey levels; their relative contents were also calculated with the software, and the data are 61.2%, 0% and 38.8% at the beginning of hydration and 11.8%, 78.5% and 9.7% at 28 d age, respectively. The hydration degree of cement paste at different ages was compared with the experimental data acquired by loss on ignition (LOI) tests. The results show that the calculated and measured data reasonably agree with each other, which indicates that micro-CT is a useful and reliable approach to characterize the micro structure evolution of hydrating cement paste.
