以D-苯甘氨酸为原料,经氨基保护和羧基活化后与邻苯二胺反应,以较高产率合成了苯并咪唑类化合物.通过1 H NMR、13C NMR、IR和X射线衍射对其结构进行了表征.同时对其进行了旋光性测定,发现以D-苯甘氨酸为原料所合成的苯并咪唑类化合物发...以D-苯甘氨酸为原料,经氨基保护和羧基活化后与邻苯二胺反应,以较高产率合成了苯并咪唑类化合物.通过1 H NMR、13C NMR、IR和X射线衍射对其结构进行了表征.同时对其进行了旋光性测定,发现以D-苯甘氨酸为原料所合成的苯并咪唑类化合物发生了外消旋化作用.展开更多
Hydroxy 5 methylphenyl)(phenyl)methyl] 2 pyridylbenzimidazole was synthesized and its crystal structure was determined by X ray four cycle diffraction method. The crystal belongs to monoclinic, space group P2 1 /c , w...Hydroxy 5 methylphenyl)(phenyl)methyl] 2 pyridylbenzimidazole was synthesized and its crystal structure was determined by X ray four cycle diffraction method. The crystal belongs to monoclinic, space group P2 1 /c , with the crystal cell parameters: a =1.351 4(5) nm, b =0.965 9(6) nm, c =1.674 0(3) nm, β =110.2 7(2)°, V =2.049 7(14) nm 3, Z=4, D c=1.269 g/cm 3, R 1= 0.057 5 . The analyses of crystal structure show that the chain structure is formed by intermolecular H bond. [WT5HZ]展开更多
文摘Hydroxy 5 methylphenyl)(phenyl)methyl] 2 pyridylbenzimidazole was synthesized and its crystal structure was determined by X ray four cycle diffraction method. The crystal belongs to monoclinic, space group P2 1 /c , with the crystal cell parameters: a =1.351 4(5) nm, b =0.965 9(6) nm, c =1.674 0(3) nm, β =110.2 7(2)°, V =2.049 7(14) nm 3, Z=4, D c=1.269 g/cm 3, R 1= 0.057 5 . The analyses of crystal structure show that the chain structure is formed by intermolecular H bond. [WT5HZ]
