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Preparation of Biodegradable Polylactic Acid/Ethyl Cellulose/Zein Composite Film and Its Effect on the Preservation of Chilled Fresh Meat
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作者 ZHOU Ling YU Ya +8 位作者 YUAN Mengting WU Dongxu CHEN Ya LIU Yanan SU Jingjing CHEN Sihan WANG Juhua SHENG Bulei XUE Xiuheng 《食品科学》 北大核心 2025年第15期324-337,共14页
In this study,composite films consisting of polylactic acid(PLA),ethyl cellulose(EC),and zein were prepared by solution casting method,and their performance and application in chilled fresh meat preservation were inve... In this study,composite films consisting of polylactic acid(PLA),ethyl cellulose(EC),and zein were prepared by solution casting method,and their performance and application in chilled fresh meat preservation were investigated.The results showed that the three materials had satisfactory compatibility in the composite film.Addition of EC and zein effectively improved the mechanical properties,thermodynamic properties,surface hydrophilicity,oxygen permeability,and degradation properties of PLA films.When the ratio of PLA to EC was 3:7,the tensile strength and elongation at break reached maximum values of 16.6 MPa and 30.5%,respectively.Moreover,under different conditions,the composite film exhibited better degradability than the PLA film.The composite film with a 3:7 ratio of PLA to EC had the best performance,with a degradation rate of 21.75%after 84 days.Chilled fresh meat wrapped with the composite film showed significantly improved antioxidant,antibacterial,and water-holding properties. 展开更多
关键词 biodegradable film polylactic acid ethyl cellulose ZEIN chilled fresh meat PRESERVATION
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负载BMP的新型组织工程骨的构建及骨缺损修复实验 被引量:6
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作者 胡稷杰 金丹 +5 位作者 全大萍 钟世镇 陈炅昊 魏宽海 赵洁 裴国献 《第一军医大学学报》 CSCD 北大核心 2005年第11期1369-1374,共6页
目的探讨以聚乳乙醇酸(poly-(D,L-lactide-co-glycolide),PLGA)、骨形态发生蛋白(BMP)、骨髓基质干细胞(BM-SCs)构建成新型组织工程骨并观察其在动物体内的成骨能力。方法制作新西兰大白兔右桡骨中段15mm骨缺损实验模型,随机分为实验组... 目的探讨以聚乳乙醇酸(poly-(D,L-lactide-co-glycolide),PLGA)、骨形态发生蛋白(BMP)、骨髓基质干细胞(BM-SCs)构建成新型组织工程骨并观察其在动物体内的成骨能力。方法制作新西兰大白兔右桡骨中段15mm骨缺损实验模型,随机分为实验组、对照组和空白组,实验组植入同时负载5mgBMP及1×106个已向成骨细胞诱导的BMSCs的PLGA、对照组植入负载1×106个已向成骨细胞诱导的BMSCs的PLGA、空白组仅植入PLGA。术后对动物进行大体观察、摄X线片观察各组不同时相骨缺损修复情况、比较不同时相的骨缺损区X线阻射密度、并于术后第4、8、12周取出骨缺损区标本进行大体观察和组织学切片观察,图像分析骨小梁的生成数量。结果实验组在12周内骨缺损完全修复,且同时期内新生骨的数量和质量显著优于对照组,空白材料组骨缺损主要由纤维结缔组织填充。结论利用含BMP的PLGA支架与BMSCs复合构建的新型组织工程骨具有良好的骨缺损修复能力。 展开更多
关键词 骨形态发生蛋白 聚乳乙醇酸 骨髓基质干细胞 组织工程
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