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非典型钙粘蛋白Celsr1-3在神经系统发育和PCP中的功能 被引量:2
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作者 曲宜波 周立兵 《暨南大学学报(自然科学与医学版)》 CAS CSCD 北大核心 2012年第4期344-350,共7页
Celsr1-3(Cadherin EGF Laminin Seven Pass Receptor 1-3)是果蝇Flamingo/starry night的哺乳动物同源基因,其编码属于钙粘蛋白家族的非典型钙粘蛋白。Celsr1-3是"核心平面细胞极性(PCP)基因"组的成员。3个Celsr基因在小鼠... Celsr1-3(Cadherin EGF Laminin Seven Pass Receptor 1-3)是果蝇Flamingo/starry night的哺乳动物同源基因,其编码属于钙粘蛋白家族的非典型钙粘蛋白。Celsr1-3是"核心平面细胞极性(PCP)基因"组的成员。3个Celsr基因在小鼠中枢神经系统发育过程中都有表达。总结有关Celsr1-3在神经系统发育和PCP中的工作。Celsr1是在脊椎动物PCP的主要参与者,在许多典型PCP事件中发挥着重要作用。Celsr2和Celsr3可调节纤毛生成,并很可能是通过PCP信号参与调控脑室管膜纤毛发生。Celsr1-3在FBM神经元迁移过程中扮演着不同的重要角色。Celsr1决定FBM神经元迁移的方向,而Celsr2和3则控制其迁移能力。越来越多的证据证明Celsr1-3在神经系统的发育、维持以及PCP中发挥着多种不同的重要作用。 展开更多
关键词 Celsr 组织极性 运动纤毛 FBM神经元
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Effect of tempering temperature on microstructure and mechanical properties of AISI 6150 steel 被引量:7
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作者 李红英 胡继东 +2 位作者 李俊 陈广 苏雄杰 《Journal of Central South University》 SCIE EI CAS 2013年第4期866-870,共5页
Effect of tempering temperature on the microstructure and mechanical properties of AISI 6150 steel was investigated. All samples were austenitized at 870 ℃ for 45 min followed by oil quenching, and then tempered at t... Effect of tempering temperature on the microstructure and mechanical properties of AISI 6150 steel was investigated. All samples were austenitized at 870 ℃ for 45 min followed by oil quenching, and then tempered at temperatures between 200 and 600 ℃ for 60 min. The results show that the microstructure of tempered sample at 200 ℃ mainly consists of tempered martensite. With increasing the tempered temperature, the martensite transforms to the ferrite and carbides. The ultimate tensile strength, the hardness and the retained austenite decrease with increasing tempered temperature, and 0.2% yield strength increases when the temperature increases from 200 to 300 ℃ and then decreases with increasing the temperature, but the elongation and impact energy increase with increasing the tempering temperature. 展开更多
关键词 tempering temperature AISI 6150 steel MICROSTRUCTURE mechanical property
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