The secondary metabolites of the fungus Cephalosporium sp.(2090#) are first reported which isolated from the mangrove sample from the South China Sea.Seven compounds are isolated from the mycelium of this strain.Their...The secondary metabolites of the fungus Cephalosporium sp.(2090#) are first reported which isolated from the mangrove sample from the South China Sea.Seven compounds are isolated from the mycelium of this strain.Their structures are identified by comprehensive spectroscopic methods.展开更多
Six alkaloids,2-(1H-indol-3-yl)-4H-benzo[d]oxazin-4-one(1),methyl o-(indole-3-carboxamido) benzoate(2),cyclo(Ile-Leu-Val-Va1)(3),cyclo(Phe-Gly)(4),cyclo(Leu-Leu)(5),and cyclo(Ala-Leu)(6),were isolated from the mangrov...Six alkaloids,2-(1H-indol-3-yl)-4H-benzo[d]oxazin-4-one(1),methyl o-(indole-3-carboxamido) benzoate(2),cyclo(Ile-Leu-Val-Va1)(3),cyclo(Phe-Gly)(4),cyclo(Leu-Leu)(5),and cyclo(Ala-Leu)(6),were isolated from the mangrove endophytic fungus ZSU-H26 from the South China Sea.Their structures were elucidated by spectral data.Indole alkaloids 1 and 2 were both isolated from microorganism for the first time.In the preliminary bioassay,1 and 2 show inhibitory activity on the hepG2 cell line with IC50 values of 20μg/mL and 35μg/mL,respectively.展开更多
文摘The secondary metabolites of the fungus Cephalosporium sp.(2090#) are first reported which isolated from the mangrove sample from the South China Sea.Seven compounds are isolated from the mycelium of this strain.Their structures are identified by comprehensive spectroscopic methods.
文摘Six alkaloids,2-(1H-indol-3-yl)-4H-benzo[d]oxazin-4-one(1),methyl o-(indole-3-carboxamido) benzoate(2),cyclo(Ile-Leu-Val-Va1)(3),cyclo(Phe-Gly)(4),cyclo(Leu-Leu)(5),and cyclo(Ala-Leu)(6),were isolated from the mangrove endophytic fungus ZSU-H26 from the South China Sea.Their structures were elucidated by spectral data.Indole alkaloids 1 and 2 were both isolated from microorganism for the first time.In the preliminary bioassay,1 and 2 show inhibitory activity on the hepG2 cell line with IC50 values of 20μg/mL and 35μg/mL,respectively.
