A processed pseudogene cDNA of PRS1 was first cloned from lymphoblast cells of normal persons and primary gout patients among Chinese. The full length of the pseudogene cDNA was 985 bp, which possessed approx. 89 7% h...A processed pseudogene cDNA of PRS1 was first cloned from lymphoblast cells of normal persons and primary gout patients among Chinese. The full length of the pseudogene cDNA was 985 bp, which possessed approx. 89 7% homology with the published sequence. Except many point mutations, two frame shift deletion of 5 bp and 8 bp were also found at the location 366 bp and 648 bp of the pseudogene cDNA, respectively. All led to 13 stop codons, so that fragment can’t translate. According to these characteristics, the fragment was thought as a processed pseudogene of PRS1.展开更多
文摘A processed pseudogene cDNA of PRS1 was first cloned from lymphoblast cells of normal persons and primary gout patients among Chinese. The full length of the pseudogene cDNA was 985 bp, which possessed approx. 89 7% homology with the published sequence. Except many point mutations, two frame shift deletion of 5 bp and 8 bp were also found at the location 366 bp and 648 bp of the pseudogene cDNA, respectively. All led to 13 stop codons, so that fragment can’t translate. According to these characteristics, the fragment was thought as a processed pseudogene of PRS1.
