The C-C coupling reaction between ethyl acetoacetate and aryl iodides,catalysted by CuI,in the presence of N-methyl glycine under microwave irradiation in DMSO was studied.It afforded an efficent protocol to synthesis...The C-C coupling reaction between ethyl acetoacetate and aryl iodides,catalysted by CuI,in the presence of N-methyl glycine under microwave irradiation in DMSO was studied.It afforded an efficent protocol to synthesis arylated acetoacetate ester.Microwave irradiation reduced reaction times obviously.Most interestingly,as the changing of bases and prolonging of reaction times,deacylated and decarboxy ester reaction resulted in succession.展开更多
文摘The C-C coupling reaction between ethyl acetoacetate and aryl iodides,catalysted by CuI,in the presence of N-methyl glycine under microwave irradiation in DMSO was studied.It afforded an efficent protocol to synthesis arylated acetoacetate ester.Microwave irradiation reduced reaction times obviously.Most interestingly,as the changing of bases and prolonging of reaction times,deacylated and decarboxy ester reaction resulted in succession.
