Luminescent terbium doped yttrium aluminum garnet (YAG∶Tb) powders were prepared using yttrium and aluminum oxide precursor particles produced by combustion process with glycine. Heat treatment of the resulting precu...Luminescent terbium doped yttrium aluminum garnet (YAG∶Tb) powders were prepared using yttrium and aluminum oxide precursor particles produced by combustion process with glycine. Heat treatment of the resulting precursor powders at 950℃or 1450℃for 2h, yielded pure YAG particles. The morphology of YAG∶Yb phosphor after sintering at 1450℃appeared to be spherical or elliptical and the grain size of the phosphor was in the range of 0.6 to 1.4μm. From the photoluminescence spectra, transitions 5D4 7FJ corresponding to Tb3+in YAG matrices were identified. The prominent transition 5D4 7F6 emission for YAG∶0.05Tb phosphor after sintering at 1450℃was very significant to improve the chromaticity of YAG∶Tb phosphor.展开更多
5-Fluorouracil(5-FU) was an antimetabolite of the pyrimidine analogue type,which was frequently used for treating colorectal,gastric tract,and liver carcinomas etc.However,the clinical applications of 5-FU were greatl...5-Fluorouracil(5-FU) was an antimetabolite of the pyrimidine analogue type,which was frequently used for treating colorectal,gastric tract,and liver carcinomas etc.However,the clinical applications of 5-FU were greatly limited by its myelosuppression,and strong intestinal toxicity.Consequently,numerous research efforts had focused on the discovery of suitable carrier-linked prodrugs with high efficiency and low toxicity.In order to decline the toxicity of 5-FU,we synthesized 2-(5-fluorouracil-1-yl-acetamido) acetic acid by liquid coupling reaction with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride(EDC·HCl) and 1-hydroxybenzotriazole(HOBt) as a coupling reagent.And the structures of the synthesized compounds were assigned by 1H NMR,13C NMR,mass spectrometry,and infrared spectroscopy,etc.展开更多
文摘Luminescent terbium doped yttrium aluminum garnet (YAG∶Tb) powders were prepared using yttrium and aluminum oxide precursor particles produced by combustion process with glycine. Heat treatment of the resulting precursor powders at 950℃or 1450℃for 2h, yielded pure YAG particles. The morphology of YAG∶Yb phosphor after sintering at 1450℃appeared to be spherical or elliptical and the grain size of the phosphor was in the range of 0.6 to 1.4μm. From the photoluminescence spectra, transitions 5D4 7FJ corresponding to Tb3+in YAG matrices were identified. The prominent transition 5D4 7F6 emission for YAG∶0.05Tb phosphor after sintering at 1450℃was very significant to improve the chromaticity of YAG∶Tb phosphor.
文摘5-Fluorouracil(5-FU) was an antimetabolite of the pyrimidine analogue type,which was frequently used for treating colorectal,gastric tract,and liver carcinomas etc.However,the clinical applications of 5-FU were greatly limited by its myelosuppression,and strong intestinal toxicity.Consequently,numerous research efforts had focused on the discovery of suitable carrier-linked prodrugs with high efficiency and low toxicity.In order to decline the toxicity of 5-FU,we synthesized 2-(5-fluorouracil-1-yl-acetamido) acetic acid by liquid coupling reaction with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride(EDC·HCl) and 1-hydroxybenzotriazole(HOBt) as a coupling reagent.And the structures of the synthesized compounds were assigned by 1H NMR,13C NMR,mass spectrometry,and infrared spectroscopy,etc.
