A new method of synthesis of 2 methyl 1 benzyl benzimidazole starting from 2 methyl benzimdazole and benzyl bromide was reported with KF Al 2O 3 as catlyst and DMF as solution.The influence of some reaction condition ...A new method of synthesis of 2 methyl 1 benzyl benzimidazole starting from 2 methyl benzimdazole and benzyl bromide was reported with KF Al 2O 3 as catlyst and DMF as solution.The influence of some reaction condition on yield was also tested,and the optimum conditions were obtained,the molecular ratio of catlyst and 2 methyl benzimdazole and benzyl bromide 1∶1∶1 05,the reaction temperature 20-25,and the yield 70 8%.展开更多
文摘A new method of synthesis of 2 methyl 1 benzyl benzimidazole starting from 2 methyl benzimdazole and benzyl bromide was reported with KF Al 2O 3 as catlyst and DMF as solution.The influence of some reaction condition on yield was also tested,and the optimum conditions were obtained,the molecular ratio of catlyst and 2 methyl benzimdazole and benzyl bromide 1∶1∶1 05,the reaction temperature 20-25,and the yield 70 8%.
