Microwave irradiation was firstly attempted to prepare molecularly imprinted polymers(MIPs)monoliths,which were in situ prepared rapidly with methacrylic acid(MAA)as a functional monomer,ethylene glycol dimethacrylate...Microwave irradiation was firstly attempted to prepare molecularly imprinted polymers(MIPs)monoliths,which were in situ prepared rapidly with methacrylic acid(MAA)as a functional monomer,ethylene glycol dimethacrylate(EDMA)as a cross-linking agent,toluene and isooctane as the porogenic solvents and AIBN as an initiator.The baseline separation of isomers of hydroxybenzoic acid was achieved on these monolithic columns with 4-HBA as the template,but not on the blank polymer.Furthermore,some neutral compounds could also be baseline-separated on the imprinted polymer columns in the modes of pressure-driven capillary electrochromatography and low-pressure driven capillary electrochromatography.It was shown that the monoliths were not only used as the molecularly imprinted polymers but also as the reverse phase chromatographic material.展开更多
A novel monolithic stationary phase with long alkyl chain ligands was introduced and evaluated in pressurized capillary electrochromatography(p-CEC) by using a mixture of neutral and charged compounds. The capillary m...A novel monolithic stationary phase with long alkyl chain ligands was introduced and evaluated in pressurized capillary electrochromatography(p-CEC) by using a mixture of neutral and charged compounds. The capillary monolithic-column was prepared by in situ copolymerization of ethylene dimethacrylate,alkyl alcohol and 2-acrylamido-2-methyl-1-propanesulfonic acid in a quadruple porogenic solvent consisting of 1,4-butanediol/cyclohexanol/docecanol/water. Effects of experimental parameters in p-CEC,such as pressure and electrical field strength,on the separation were investigated. The baseline separation of the components in the mixture was achieved. The monolithic column can be used as an alternative to the conventional capillary column such as the reversed phase ODS.展开更多
文摘Microwave irradiation was firstly attempted to prepare molecularly imprinted polymers(MIPs)monoliths,which were in situ prepared rapidly with methacrylic acid(MAA)as a functional monomer,ethylene glycol dimethacrylate(EDMA)as a cross-linking agent,toluene and isooctane as the porogenic solvents and AIBN as an initiator.The baseline separation of isomers of hydroxybenzoic acid was achieved on these monolithic columns with 4-HBA as the template,but not on the blank polymer.Furthermore,some neutral compounds could also be baseline-separated on the imprinted polymer columns in the modes of pressure-driven capillary electrochromatography and low-pressure driven capillary electrochromatography.It was shown that the monoliths were not only used as the molecularly imprinted polymers but also as the reverse phase chromatographic material.
文摘A novel monolithic stationary phase with long alkyl chain ligands was introduced and evaluated in pressurized capillary electrochromatography(p-CEC) by using a mixture of neutral and charged compounds. The capillary monolithic-column was prepared by in situ copolymerization of ethylene dimethacrylate,alkyl alcohol and 2-acrylamido-2-methyl-1-propanesulfonic acid in a quadruple porogenic solvent consisting of 1,4-butanediol/cyclohexanol/docecanol/water. Effects of experimental parameters in p-CEC,such as pressure and electrical field strength,on the separation were investigated. The baseline separation of the components in the mixture was achieved. The monolithic column can be used as an alternative to the conventional capillary column such as the reversed phase ODS.
