目的观察两种不同治疗参数下气压弹道式体外冲击波对脑卒中后下肢痉挛的疗效及差异,为今后气压弹道式体外冲击波治疗脑卒中后肌肉痉挛提供临床试验参考。方法采用二阶段交叉设计的试验方法,选择12例脑卒中后下肢肌肉痉挛患者,随机平均...目的观察两种不同治疗参数下气压弹道式体外冲击波对脑卒中后下肢痉挛的疗效及差异,为今后气压弹道式体外冲击波治疗脑卒中后肌肉痉挛提供临床试验参考。方法采用二阶段交叉设计的试验方法,选择12例脑卒中后下肢肌肉痉挛患者,随机平均分为两组(A组和B组,每组各6例患者),在常规治疗的基础上,接受冲击波治疗1次,A组参数为(参数设置为压力强度1.0 bar,频率8 Hz),B组参数为(参数设置为压力强度1.6 bar,频率20 Hz),冲击次数均为3000次,在经过10天的清洗期后,两组交换,原A组的患者接受B组参数冲击,原B组的患者接受A组参数冲击。比较治疗前、治疗结束后即刻两组患者踝关节被动活动度(positive range of motion,PROM)、改良Tardieu量表(modified Tardieu scale,MTS)。结果两组的PROM和MTS中R1较治疗前均有所增加(P<0.01),MTS中(x)分级较治疗前有所下降,但无显著差异(P>0.05),两组比较PROM和R1,虽A组均数略低于B组,但两组比较差异无显著性。两组患者在整个试验过程中均未观察到任何不良反应。结论单次气压弹道式冲击波对脑卒中后腓肠肌痉挛有即时的缓解作用,但其最佳治疗参数仍有待进一步研究。展开更多
Taking the ratio of heat transfer area to net power and heat recovery efficiency into account, a multi-objective mathematical model was developed for organic Rankine cycle （ORC）. Working fluids considered were R123,...Taking the ratio of heat transfer area to net power and heat recovery efficiency into account, a multi-objective mathematical model was developed for organic Rankine cycle （ORC）. Working fluids considered were R123, R134a, R141b, R227ea and R245fa. Under the given conditions, the parameters including evaporating and condensing pressures, working fluid and cooling water velocities were optimized by simulated annealing algorithm. The results show that the optimal evaporating pressure increases with the heat source temperature increasing. Compared with other working fluids, R123 is the best choice for the temperature range of 100--180℃ and R141 b shows better performance when the temperature is higher than 180 ℃. Economic characteristic of system decreases rapidly with the decrease of heat source temperature. ORC system is uneconomical for the heat source temperature lower than 100℃.展开更多
文摘目的观察两种不同治疗参数下气压弹道式体外冲击波对脑卒中后下肢痉挛的疗效及差异,为今后气压弹道式体外冲击波治疗脑卒中后肌肉痉挛提供临床试验参考。方法采用二阶段交叉设计的试验方法,选择12例脑卒中后下肢肌肉痉挛患者,随机平均分为两组(A组和B组,每组各6例患者),在常规治疗的基础上,接受冲击波治疗1次,A组参数为(参数设置为压力强度1.0 bar,频率8 Hz),B组参数为(参数设置为压力强度1.6 bar,频率20 Hz),冲击次数均为3000次,在经过10天的清洗期后,两组交换,原A组的患者接受B组参数冲击,原B组的患者接受A组参数冲击。比较治疗前、治疗结束后即刻两组患者踝关节被动活动度(positive range of motion,PROM)、改良Tardieu量表(modified Tardieu scale,MTS)。结果两组的PROM和MTS中R1较治疗前均有所增加(P<0.01),MTS中(x)分级较治疗前有所下降,但无显著差异(P>0.05),两组比较PROM和R1,虽A组均数略低于B组,但两组比较差异无显著性。两组患者在整个试验过程中均未观察到任何不良反应。结论单次气压弹道式冲击波对脑卒中后腓肠肌痉挛有即时的缓解作用,但其最佳治疗参数仍有待进一步研究。
基金Project(2009GK2009) supported by Science and Technology Department Funds of Hunan Province,ChinaProject(08C26224302178) supported by Innovation Fund for Technology Based Firms of China
文摘Taking the ratio of heat transfer area to net power and heat recovery efficiency into account, a multi-objective mathematical model was developed for organic Rankine cycle （ORC）. Working fluids considered were R123, R134a, R141b, R227ea and R245fa. Under the given conditions, the parameters including evaporating and condensing pressures, working fluid and cooling water velocities were optimized by simulated annealing algorithm. The results show that the optimal evaporating pressure increases with the heat source temperature increasing. Compared with other working fluids, R123 is the best choice for the temperature range of 100--180℃ and R141 b shows better performance when the temperature is higher than 180 ℃. Economic characteristic of system decreases rapidly with the decrease of heat source temperature. ORC system is uneconomical for the heat source temperature lower than 100℃.
