For increasing The power of isobaric identification in accelerator mass spectrometry measurements, a new detector called gas-filled time of fight spectrometric detector was set up. The principle, construction and The ...For increasing The power of isobaric identification in accelerator mass spectrometry measurements, a new detector called gas-filled time of fight spectrometric detector was set up. The principle, construction and The results of first on-line test were desmontrated.展开更多
建立了液相色谱-四极杆飞行时间质谱（LC-Q-TOF/MS）对饲料中非目标污染物（兽药）的筛查方法,以及未知物的判定和确认技术。饲料样品经0.1%EDTA-乙腈-甲醇（1∶1∶1,含0.1%甲酸）混合溶液提取,Q-TOF全扫描模式采集数据,数据经过峰对齐...建立了液相色谱-四极杆飞行时间质谱（LC-Q-TOF/MS）对饲料中非目标污染物（兽药）的筛查方法,以及未知物的判定和确认技术。饲料样品经0.1%EDTA-乙腈-甲醇（1∶1∶1,含0.1%甲酸）混合溶液提取,Q-TOF全扫描模式采集数据,数据经过峰对齐（质量误差5 m Da以内）、噪音过滤、自动排除无用峰等处理后,进行正交偏最小二乘判别分析（OPLS-DA）处理,根据Score图、S-Plot图和VIP图判定出特征离子,结合二级信息与自建谱库比对,进行结构式确认,或通过同位素丰度比例和分子式生成功能,确认分子式,结合二级断裂信息,判定特征离子的结构式,从而判定未知物的成分。结果显示：16份饲料样品共筛查出27种兽药。采用液相色谱-三重四极杆串联质谱法对其中的12种兽药进行定性定量分析,验证结果仅出现2个假阳性,兽药含量在12.5~152.0 mg/kg之间。通过LC-Q-TOF/MS结合OPLS-DA的方法能够对饲料中的非目标物进行筛查分析,方法准确度高。展开更多
In order to improve the power of isobaric identification in the accelerator mass spectrometry, an improved gas detector called gas-filled time-of-flight (GF-TOF) spectrometric detectortern were descrient ion energy,ha...In order to improve the power of isobaric identification in the accelerator mass spectrometry, an improved gas detector called gas-filled time-of-flight (GF-TOF) spectrometric detectortern were descrient ion energy,has been designed and set up again. The experimental tests of the new system were described. ^36GS and ^36Cl were identified by GF-TOF and ΔE-E method with different ion energy, respectively.展开更多
The accelerator mass spectrometry system(AMS) in China Institute of Atomic Energy(CIAE) has been improved especially for the ion source, some new measurement methods including 41Ca measurement, PX-AMS method and GF-TO...The accelerator mass spectrometry system(AMS) in China Institute of Atomic Energy(CIAE) has been improved especially for the ion source, some new measurement methods including 41Ca measurement, PX-AMS method and GF-TOF detector are developed, the applications of the AMS system including nuclear physics science, environmental science, geoscience, life science and materials science have been carried out, a brief describe of all these work is discussed in this paper.展开更多
文摘For increasing The power of isobaric identification in accelerator mass spectrometry measurements, a new detector called gas-filled time of fight spectrometric detector was set up. The principle, construction and The results of first on-line test were desmontrated.
文摘建立了液相色谱-四极杆飞行时间质谱（LC-Q-TOF/MS）对饲料中非目标污染物（兽药）的筛查方法,以及未知物的判定和确认技术。饲料样品经0.1%EDTA-乙腈-甲醇（1∶1∶1,含0.1%甲酸）混合溶液提取,Q-TOF全扫描模式采集数据,数据经过峰对齐（质量误差5 m Da以内）、噪音过滤、自动排除无用峰等处理后,进行正交偏最小二乘判别分析（OPLS-DA）处理,根据Score图、S-Plot图和VIP图判定出特征离子,结合二级信息与自建谱库比对,进行结构式确认,或通过同位素丰度比例和分子式生成功能,确认分子式,结合二级断裂信息,判定特征离子的结构式,从而判定未知物的成分。结果显示：16份饲料样品共筛查出27种兽药。采用液相色谱-三重四极杆串联质谱法对其中的12种兽药进行定性定量分析,验证结果仅出现2个假阳性,兽药含量在12.5~152.0 mg/kg之间。通过LC-Q-TOF/MS结合OPLS-DA的方法能够对饲料中的非目标物进行筛查分析,方法准确度高。
文摘In order to improve the power of isobaric identification in the accelerator mass spectrometry, an improved gas detector called gas-filled time-of-flight (GF-TOF) spectrometric detectortern were descrient ion energy,has been designed and set up again. The experimental tests of the new system were described. ^36GS and ^36Cl were identified by GF-TOF and ΔE-E method with different ion energy, respectively.
文摘The accelerator mass spectrometry system(AMS) in China Institute of Atomic Energy(CIAE) has been improved especially for the ion source, some new measurement methods including 41Ca measurement, PX-AMS method and GF-TOF detector are developed, the applications of the AMS system including nuclear physics science, environmental science, geoscience, life science and materials science have been carried out, a brief describe of all these work is discussed in this paper.
