The amino acid tailed porphyrin and their zinc complexes were firstly synthesized. They were characterized by FAB-MS, IR, UV-Vis, elemental analysis and chemical analysis.
The synthesized chiral amino acid modified porphyrinatozinc(II) exhibited characterized CD spectrum in Soret region. The coupling between the carbonyl group of the amino acid residue and the porphyrin unit is the orig...The synthesized chiral amino acid modified porphyrinatozinc(II) exhibited characterized CD spectrum in Soret region. The coupling between the carbonyl group of the amino acid residue and the porphyrin unit is the origin of the CD spectrum. The premise of the above coupling is the intramolecular interaction between the amino acid residue and the porphyrin unit.展开更多
Tetra\{\[4\|carboxymethoxyphenyl\]\}porphyrin copper(Ⅱ), nickel(Ⅱ), zinc(Ⅱ) complex and their dibutyltin(Ⅳ) ester derivatives have been synthesized and characterized. The equilibrium constants of the aggregation o...Tetra\{\[4\|carboxymethoxyphenyl\]\}porphyrin copper(Ⅱ), nickel(Ⅱ), zinc(Ⅱ) complex and their dibutyltin(Ⅳ) ester derivatives have been synthesized and characterized. The equilibrium constants of the aggregation of the metal porphyrin and the equilibrium constant of the π\|π coordination with phenothoroline have been measured by using UV\|Vis titration method. The results show that the equilibrium constants decrease in the order of K \-\{CuP\}> K \-\{NiP\}> K \-\{ZnP\}. The vitro anti\|tumor activities of the dibutyltin(Ⅳ) metal porphyrinate has some relation with the ability of aggregation and coordination with ligand of the metal porphyrin.展开更多
文摘The amino acid tailed porphyrin and their zinc complexes were firstly synthesized. They were characterized by FAB-MS, IR, UV-Vis, elemental analysis and chemical analysis.
文摘The synthesized chiral amino acid modified porphyrinatozinc(II) exhibited characterized CD spectrum in Soret region. The coupling between the carbonyl group of the amino acid residue and the porphyrin unit is the origin of the CD spectrum. The premise of the above coupling is the intramolecular interaction between the amino acid residue and the porphyrin unit.
文摘Tetra\{\[4\|carboxymethoxyphenyl\]\}porphyrin copper(Ⅱ), nickel(Ⅱ), zinc(Ⅱ) complex and their dibutyltin(Ⅳ) ester derivatives have been synthesized and characterized. The equilibrium constants of the aggregation of the metal porphyrin and the equilibrium constant of the π\|π coordination with phenothoroline have been measured by using UV\|Vis titration method. The results show that the equilibrium constants decrease in the order of K \-\{CuP\}> K \-\{NiP\}> K \-\{ZnP\}. The vitro anti\|tumor activities of the dibutyltin(Ⅳ) metal porphyrinate has some relation with the ability of aggregation and coordination with ligand of the metal porphyrin.