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^125I粒子内放疗联合化疗治疗中晚期肺癌52例疗效分析 被引量:6
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作者 田立景 田秀荣 《中国肿瘤临床》 CAS CSCD 北大核心 2008年第2期82-84,共3页
肺癌是严重威胁人类健康的恶性肿瘤之一。非小细胞肺癌(non-small cell lung cancer,NSCLC)约占所有肺癌的75%-80%,而就诊时多为中晚期患者,约占70%,5年总体生存率低于15%。近年来。^125I粒子内放疗对肺癌的减瘤效果开始引起... 肺癌是严重威胁人类健康的恶性肿瘤之一。非小细胞肺癌(non-small cell lung cancer,NSCLC)约占所有肺癌的75%-80%,而就诊时多为中晚期患者,约占70%,5年总体生存率低于15%。近年来。^125I粒子内放疗对肺癌的减瘤效果开始引起关注.而联合化疗的临床疗效评价报道较少。 展开更多
关键词 ^125I粒子内 放效分析 肺癌
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Large-scale two-dimensional nonlinear FE analysis on PGA amplification effect with depth and focusing effect of Fuzhou Basin 被引量:2
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作者 金丹丹 陈国兴 董菲蕃 《Journal of Central South University》 SCIE EI CAS 2014年第7期2894-2903,共10页
Based on the explicit finite element(FE) method and platform of ABAQUS,considering both the inhomogeneity of soils and concave-convex fluctuation of topography,a large-scale refined two-dimensional(2D) FE nonlinear an... Based on the explicit finite element(FE) method and platform of ABAQUS,considering both the inhomogeneity of soils and concave-convex fluctuation of topography,a large-scale refined two-dimensional(2D) FE nonlinear analytical model for Fuzhou Basin was established.The peak ground motion acceleration(PGA) and focusing effect with depth were analyzed.Meanwhile,the results by wave propagation of one-dimensional(1D) layered medium equivalent linearization method were added for contrast.The results show that:1) PGA at different depths are obviously amplified compared to the input ground motion,amplification effect of both funnel-shaped depression and upheaval areas(based on the shape of bedrock surface) present especially remarkable.The 2D results indicate that the PGA displays a non-monotonic decreasing with depth and a greater focusing effect of some particular layers,while the 1D results turn out that the PGA decreases with depth,except that PGA at few particular depth increases abruptly; 2) To the funnel-shaped depression areas,PGA amplification effect above 8 m depth shows relatively larger,to the upheaval areas,PGA amplification effect from 15 m to 25 m depth seems more significant.However,the regularities of the PGA amplification effect could hardly be found in the rest areas; 3) It appears a higher regression rate of PGA amplification coefficient with depth when under a smaller input motion; 4) The frequency spectral characteristic of input motion has noticeable effects on PGA amplification tendency. 展开更多
关键词 seismic effect of basin LARGE-SCALE fluctuation of topography inhomogeneity site focusing effect two-dimensional refined finite element model nonlinear analysis
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Near-source topographic effect on seismic responses of a multi-span continuous railway bridge crossing a symmetrical V-shaped canyon 被引量:2
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作者 LI Shuai WANG Ming-dong +5 位作者 ZHANG Fan ZHANG Yu DAI Deng-hui ZHANG Ning WANG Jing-quan GAO Yu-feng 《Journal of Central South University》 SCIE EI CAS CSCD 2022年第8期2434-2448,共15页
Past earthquakes have revealed that topographic features have significant impacts on the characteristics of ground motions,which may cause the amplification and de-amplification of input seismic waves.The topographic ... Past earthquakes have revealed that topographic features have significant impacts on the characteristics of ground motions,which may cause the amplification and de-amplification of input seismic waves.The topographic effect with the assumption of plane seismic waves on the seismic responses of bridges has been investigated in the existing literature;however,the influence of near-source topographic effects has not been thoroughly understood.The objective of this study is to numerically explore the near-source topographic effects on the seismic behaviors of an existing railway bridge crossing a symmetrical V-shaped canyon.The influence of the source of incident waves is estimated.Numerical results demonstrate that the topographic effects can noticeably amplify the seismic responses of the bridge.Compared to the bridge without crossing a canyon,the peak displacements of the girder,pier,and bearing in the case of the canyon crossing bridge increase by 15.2%,2.9%−14.5%,and 24.2%−229.6%,respectively.The piers at the illuminated side of the canyon experience larger seismic responses compared to the piers at the shaded side of the canyon due to the unequal motion amplitudes at each support.As the source-to-canyon distance increases,the seismic responses of the piers show an increasing trend. 展开更多
关键词 railway bridges V-shaped canyon topographic amplification seismic response parametric analysis
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Distribution of acceleration and empirical formula for calculating maximum acceleration of rockfill dams
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作者 周晖 李俊杰 康飞 《Journal of Central South University》 SCIE EI CAS 2010年第3期642-647,共6页
To find the distribution patterns of dynamic amplification coefficients for dams subjected to earthquake, 3D seismic responses of concrete-faced rockfill dams with different heights and different shapes of river valle... To find the distribution patterns of dynamic amplification coefficients for dams subjected to earthquake, 3D seismic responses of concrete-faced rockfill dams with different heights and different shapes of river valley were analyzed by using the equivalent-linear model. Statistical analysis was also made to the seismic coefficient, and an empirical formula for calculating the maximum acceleration was provided. The results indicate that under the condition of the same dam height and the same base acceleration excitations, with the increase of the river valley width, the position of the maximum acceleration on the axis of the top of the dam moves from the center to the riversides symmetrically. For the narrow valleys, the maximum acceleration occurs in the middle of the axis at the top of the dam; for wide valleys the maximum acceleration appears near the riversides. The result negates the application of 2D dynamical computation for wide valleys, and shows that for the seismic response of high concrete-faced rockfill dams, the seismic coefficient along the axis should be given, except for that along the dam height. Seismic stability analysis of rockfill dams using pseudo-static method can be modified according to the formula. 展开更多
关键词 concrete-faced rockfill dam 3D dynamical response analysis equivalent-linear method ACCELERATION seismic coefficient statistical analysis
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