By semi analytic approach, the estimate of the properties of the largest virialized dark halos in the present universe is presented for three different scenarios of structure formation: SCDM, ΛCDM and OCDM models. Th...By semi analytic approach, the estimate of the properties of the largest virialized dark halos in the present universe is presented for three different scenarios of structure formation: SCDM, ΛCDM and OCDM models. The resulting virial mass increases from the lowest values of 1.6×10 15 h -1 M ⊙ in OCDM, the mid range values of 9.0×10 15 h -1 M ⊙ in ΛCDM, to the highest values of 20.9×10 15 h -1 M ⊙ in SCDM. As compared with the largest virialized object seen in the universe, the OCDM model can safely be ruled out. Therefore, the computation in this paper favors the prevailing ΛCDM model in which superclusters may be marginally regarded as dynamically virialized systems.展开更多
文摘研究表明，80％的肝细胞癌（ hepatocellular carcinoma ，HCC）是由于肝纤维化和炎症引起的［1］。肝星状细胞可被肝损伤等激活为肌成纤维细胞样表型，活化的肝星状细胞可参与肿瘤微环境的形成［2］；肿瘤血管生成与肿瘤微环境的形成有密切关系［3］。先前的研究证明，8-溴-7-甲氧基白杨素（8-bromo-7-methoxychrysin ， BrMC）具有靶向抑制肝癌干细胞作用［4－5］。本文旨在研究BrMC是否可以抑制肝癌相关星状细胞诱导内皮细胞管结构形成，并探讨其作用机制是否涉及抑制信号转导子和转录激活子-3（ signal transducer and acti-vator of transcription-3， STAT3）激活。
文摘By semi analytic approach, the estimate of the properties of the largest virialized dark halos in the present universe is presented for three different scenarios of structure formation: SCDM, ΛCDM and OCDM models. The resulting virial mass increases from the lowest values of 1.6×10 15 h -1 M ⊙ in OCDM, the mid range values of 9.0×10 15 h -1 M ⊙ in ΛCDM, to the highest values of 20.9×10 15 h -1 M ⊙ in SCDM. As compared with the largest virialized object seen in the universe, the OCDM model can safely be ruled out. Therefore, the computation in this paper favors the prevailing ΛCDM model in which superclusters may be marginally regarded as dynamically virialized systems.
