In this paper,a novel train positioning method considering satellite raw observation data was proposed,which aims to promote train positioning performance from an innovative perspective of the train satellite-based po...In this paper,a novel train positioning method considering satellite raw observation data was proposed,which aims to promote train positioning performance from an innovative perspective of the train satellite-based positioning error sources.The method focused on overcoming the abnormal observations in satellite observation data caused by railway environment rather than the positioning results.Specifically,the relative positioning experimental platform was built and the zero-baseline method was firstly employed to evaluate the carrier phase data quality,and then,GNSS combined observation models were adopted to construct the detection values,which were applied to judge abnormal-data through the dual-frequency observations.Further,ambiguity fixing optimization was investigated based on observation data selection in partly-blocked environments.The results show that the proposed method can effectively detect and address abnormal observations and improve positioning stability.Cycle slips and gross errors can be detected and identified based on dual-frequency global navigation satellite system data.After adopting the data selection strategy,the ambiguity fixing percentage was improved by 29.2%,and the standard deviation in the East,North,and Up components was enhanced by 12.7%,7.4%,and 12.5%,respectively.The proposed method can provide references for train positioning performance optimization in railway environments from the perspective of positioning error sources.展开更多
The gut microbiota is a complex ecosystem composed of many bacteria and their metabolites.It plays an irreplaceable role in human digestion,nutrient absorption,energy supply,fat metabolism,immune regulation,and many o...The gut microbiota is a complex ecosystem composed of many bacteria and their metabolites.It plays an irreplaceable role in human digestion,nutrient absorption,energy supply,fat metabolism,immune regulation,and many other aspects.Exploring the structure and function of the gut microbiota,as well as their key genes and metabolites,will enable the early diagnosis and auxiliary diagnosis of diseases,new treatment methods,better effects of drug treatments,and better guidance in the use of antibiotics.The identification of gut microbiota plays an important role in clinical diagnosis and treatment,as well as in drug research and development.Therefore,it is necessary to conduct a comprehensive review of this rapidly evolving topic.Traditional identification methods cannot comprehensively capture the diversity of gut microbiota.Currently,with the rapid development of molecular biology,the classification and identification methods for gut microbiota have evolved from the initial phenotypic and chemical identification to identification at the molecular level.This review integrates the main methods of gut microbiota identification and evaluates their application.We pay special attention to the research progress on molecular biological methods and focus on the application of high-throughput sequencing technology in the identification of gut microbiota.This revolutionary method for intestinal flora identification heralds a new chapter in our understanding of the microbial world.展开更多
Controlled laboratory experiments are proved to be a valuable tool for investigating changes in underground physical properties and the related response of surface geophysical signals.The self-potential(SP)method is w...Controlled laboratory experiments are proved to be a valuable tool for investigating changes in underground physical properties and the related response of surface geophysical signals.The self-potential(SP)method is widely used in mineral resource exploration due to its direct correlation with underground electrochemical gradients.This paper presented the design and construction of an experimental platform based on a multi-channel SP monitoring system.The proposed platform was used to monitor the anodizing corrosion process of different metal blocks from a laboratory perspective,record the real-time SP signal generated by the redox reaction,as well as investigate the geobattery mechanism associated with the natural polarization process of metal mineral resources.The experimental results demonstrate that the constructed SP monitoring platform effectively captures time-series SP signals and provides direct laboratory evidence for the geobattery model.The measured SP data were quantitatively interpreted using the simulated annealing algorithm,and the inversion results closely match the real model.This finding highlights the potential of the SP method as a promising tool for determining the location and spatial distribution of underground polarizers.The study holds reference value for the exploration and exploitation of mineral resources in both terrestrial and marine environments.展开更多
基金Project(52272339)supported by the National Natural Science Foundation of ChinaProject(2023YFB390730303)supported by the National Key Research and Development Program of China+2 种基金Project(L2023G004)supported by the Science and Technology Research and Development Program of China State Railway Group Co.,Ltd.Project(QZKFKT2023-005)supported by the State Key Laboratory of Heavy-duty and Express High-power Electric Locomotive,ChinaProject(2022JZZ05)supported by the Open Foundation of MOE Key Laboratory of Engineering Structures of Heavy Haul Railway(Central South University),China。
文摘In this paper,a novel train positioning method considering satellite raw observation data was proposed,which aims to promote train positioning performance from an innovative perspective of the train satellite-based positioning error sources.The method focused on overcoming the abnormal observations in satellite observation data caused by railway environment rather than the positioning results.Specifically,the relative positioning experimental platform was built and the zero-baseline method was firstly employed to evaluate the carrier phase data quality,and then,GNSS combined observation models were adopted to construct the detection values,which were applied to judge abnormal-data through the dual-frequency observations.Further,ambiguity fixing optimization was investigated based on observation data selection in partly-blocked environments.The results show that the proposed method can effectively detect and address abnormal observations and improve positioning stability.Cycle slips and gross errors can be detected and identified based on dual-frequency global navigation satellite system data.After adopting the data selection strategy,the ambiguity fixing percentage was improved by 29.2%,and the standard deviation in the East,North,and Up components was enhanced by 12.7%,7.4%,and 12.5%,respectively.The proposed method can provide references for train positioning performance optimization in railway environments from the perspective of positioning error sources.
文摘The gut microbiota is a complex ecosystem composed of many bacteria and their metabolites.It plays an irreplaceable role in human digestion,nutrient absorption,energy supply,fat metabolism,immune regulation,and many other aspects.Exploring the structure and function of the gut microbiota,as well as their key genes and metabolites,will enable the early diagnosis and auxiliary diagnosis of diseases,new treatment methods,better effects of drug treatments,and better guidance in the use of antibiotics.The identification of gut microbiota plays an important role in clinical diagnosis and treatment,as well as in drug research and development.Therefore,it is necessary to conduct a comprehensive review of this rapidly evolving topic.Traditional identification methods cannot comprehensively capture the diversity of gut microbiota.Currently,with the rapid development of molecular biology,the classification and identification methods for gut microbiota have evolved from the initial phenotypic and chemical identification to identification at the molecular level.This review integrates the main methods of gut microbiota identification and evaluates their application.We pay special attention to the research progress on molecular biological methods and focus on the application of high-throughput sequencing technology in the identification of gut microbiota.This revolutionary method for intestinal flora identification heralds a new chapter in our understanding of the microbial world.
基金Project(42174170)supported by the National Natural Science Foundation of China。
文摘Controlled laboratory experiments are proved to be a valuable tool for investigating changes in underground physical properties and the related response of surface geophysical signals.The self-potential(SP)method is widely used in mineral resource exploration due to its direct correlation with underground electrochemical gradients.This paper presented the design and construction of an experimental platform based on a multi-channel SP monitoring system.The proposed platform was used to monitor the anodizing corrosion process of different metal blocks from a laboratory perspective,record the real-time SP signal generated by the redox reaction,as well as investigate the geobattery mechanism associated with the natural polarization process of metal mineral resources.The experimental results demonstrate that the constructed SP monitoring platform effectively captures time-series SP signals and provides direct laboratory evidence for the geobattery model.The measured SP data were quantitatively interpreted using the simulated annealing algorithm,and the inversion results closely match the real model.This finding highlights the potential of the SP method as a promising tool for determining the location and spatial distribution of underground polarizers.The study holds reference value for the exploration and exploitation of mineral resources in both terrestrial and marine environments.
基金The National Natural Science Foundation of China(31071775)The Science and Technology Department of Zhejiang Province(2008C24006)The Zhejiang Normal University Innovative Research Team Program
