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基于MOGA和BPNN-GA优化黄连厚朴汤抗流感活性成分的提取工艺 被引量:2
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作者 吴巧凤 严云良 +1 位作者 孙瑶 曹志明 《中华中医药学刊》 CAS 北大核心 2022年第4期1-5,共5页
目的确定黄连厚朴汤抗流感活性成分的提取工艺。方法以液料比、提取时间、提取温度和提取次数为考察因素,进行正交设计,以盐酸小檗碱与厚朴酚含量、浸膏得率及病毒抑制率为考察指标,熵权法赋权得到综合评分,再分别采用多目标遗传算法(mu... 目的确定黄连厚朴汤抗流感活性成分的提取工艺。方法以液料比、提取时间、提取温度和提取次数为考察因素,进行正交设计,以盐酸小檗碱与厚朴酚含量、浸膏得率及病毒抑制率为考察指标,熵权法赋权得到综合评分,再分别采用多目标遗传算法(multiple objective genetic algorithm,MOGA)和BP神经网络结合遗传算法(BP neural network combined with genetic algorithm,BPNN-GA)进行建模并目标寻优,比较2种方法的优劣性,以确定黄连厚朴汤抗流感活性成分的最佳提取工艺。结果正交法、MOGA和BPNN-GA的综合评分依次为22.63、23.57和24.20,BPNN-GA得到的综合评分最高,且与正交结果存在显著性差异。故选用BPNN-GA所得为最佳提取工艺条件,即:药材加9倍量的水,于72℃提取3次,每次54 min,平均综合评分为24.20。结论MOGA和BPNN-GA均可用于黄连厚朴汤的提取工艺优化,且BPNN-GA优化所得的工艺更为节能高效。结果可为中药多种活性成分的提取提供参考。 展开更多
关键词 黄连厚朴汤 正交试验 多目标遗传算法模型 BP神经网络结合遗传算法模型 提取工艺
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Multi-objective optimization of stamping forming process of head using Pareto-based genetic algorithm 被引量:10
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作者 周杰 卓芳 +1 位作者 黄磊 罗艳 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第9期3287-3295,共9页
To obtain the optimal process parameters of stamping forming, finite element analysis and optimization technique were integrated via transforming multi-objective issue into a single-objective issue. A Pareto-based gen... To obtain the optimal process parameters of stamping forming, finite element analysis and optimization technique were integrated via transforming multi-objective issue into a single-objective issue. A Pareto-based genetic algorithm was applied to optimizing the head stamping forming process. In the proposed optimal model, fracture, wrinkle and thickness varying are a function of several factors, such as fillet radius, draw-bead position, blank size and blank-holding force. Hence, it is necessary to investigate the relationship between the objective functions and the variables in order to make objective functions varying minimized simultaneously. Firstly, the central composite experimental(CCD) with four factors and five levels was applied, and the experimental data based on the central composite experimental were acquired. Then, the response surface model(RSM) was set up and the results of the analysis of variance(ANOVA) show that it is reliable to predict the fracture, wrinkle and thickness varying functions by the response surface model. Finally, a Pareto-based genetic algorithm was used to find out a set of Pareto front, which makes fracture, wrinkle and thickness varying minimized integrally. A head stamping case indicates that the present method has higher precision and practicability compared with the "trial and error" procedure. 展开更多
关键词 stamping forming HEADS finite element analysis central composite experimental design response surface methodology multi-objective genetic algorithm
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Optimal design of structural parameters for shield cutterhead based on fuzzy mathematics and multi-objective genetic algorithm 被引量:12
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作者 夏毅敏 唐露 +2 位作者 暨智勇 程永亮 卞章括 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第3期937-945,共9页
In order to improve the strength and stiffness of shield cutterhead, the method of fuzzy mathematics theory in combination with the finite element analysis is adopted. An optimal design model of structural parameters ... In order to improve the strength and stiffness of shield cutterhead, the method of fuzzy mathematics theory in combination with the finite element analysis is adopted. An optimal design model of structural parameters for shield cutterhead is formulated,based on the complex engineering technical requirements. In the model, as the objective function of the model is a composite function of the strength and stiffness, the response surface method is applied to formulate the approximate function of objective function in order to reduce the solution scale of optimal problem. A multi-objective genetic algorithm is used to solve the cutterhead structure design problem and the change rule of the stress-strain with various structural parameters as well as their optimal values were researched under specific geological conditions. The results show that compared with original cutterhead structure scheme, the obtained optimal scheme of the cutterhead structure can greatly improve the strength and stiffness of the cutterhead, which can be seen from the reduction of its maximum equivalent stress by 21.2%, that of its maximum deformation by 0.75%, and that of its mass by 1.04%. 展开更多
关键词 shield tunneling machine cutterhead structural parameters fuzzy mathematics finite element optimization
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Application of camera calibrating model to space manipulator with multi-objective genetic algorithm
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作者 王中宇 江文松 王岩庆 《Journal of Central South University》 SCIE EI CAS CSCD 2016年第8期1937-1943,共7页
The multi-objective genetic algorithm(MOGA) is proposed to calibrate the non-linear camera model of a space manipulator to improve its locational accuracy. This algorithm can optimize the camera model by dynamic balan... The multi-objective genetic algorithm(MOGA) is proposed to calibrate the non-linear camera model of a space manipulator to improve its locational accuracy. This algorithm can optimize the camera model by dynamic balancing its model weight and multi-parametric distributions to the required accuracy. A novel measuring instrument of space manipulator is designed to orbital simulative motion and locational accuracy test. The camera system of space manipulator, calibrated by MOGA algorithm, is used to locational accuracy test in this measuring instrument. The experimental result shows that the absolute errors are [0.07, 1.75] mm for MOGA calibrating model, [2.88, 5.95] mm for MN method, and [1.19, 4.83] mm for LM method. Besides, the composite errors both of LM method and MN method are approximately seven times higher that of MOGA calibrating model. It is suggested that the MOGA calibrating model is superior both to LM method and MN method. 展开更多
关键词 space manipulator camera calibration multi-objective genetic algorithm orbital simulation and measurement
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An integer multi-objective optimization model and an enhanced non-dominated sorting genetic algorithm for contraflow scheduling problem
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作者 李沛恒 楼颖燕 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第6期2399-2405,共7页
To determine the onset and duration of contraflow evacuation, a multi-objective optimization(MOO) model is proposed to explicitly consider both the total system evacuation time and the operation cost. A solution algor... To determine the onset and duration of contraflow evacuation, a multi-objective optimization(MOO) model is proposed to explicitly consider both the total system evacuation time and the operation cost. A solution algorithm that enhances the popular evolutionary algorithm NSGA-II is proposed to solve the model. The algorithm incorporates preliminary results as prior information and includes a meta-model as an alternative to evaluation by simulation. Numerical analysis of a case study suggests that the proposed formulation and solution algorithm are valid, and the enhanced NSGA-II outperforms the original algorithm in both convergence to the true Pareto-optimal set and solution diversity. 展开更多
关键词 hurricane evacuation contraflow scheduling multi-objective optimization NSGA-II
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