Aim To study the effect of Semen litchi effective part group （SLEPG） on insulin resistance in human adi- pocyte. Methods Primary adipocyte was obtained from fat tissue in liposuction patient and insulin resistance m...Aim To study the effect of Semen litchi effective part group （SLEPG） on insulin resistance in human adi- pocyte. Methods Primary adipocyte was obtained from fat tissue in liposuction patient and insulin resistance model was built up with dexamethasone induction. Gop-pod method was used to determine glucose in culture supematant and RT-PCR was used to assay RETN of treated cells. Results SLEPG increased the glucose consumption and ab- sorption in dexamethasone-induced insulin resistance in primary adipocyte culture. SLEC inhibited the mRNA expres- sion of RETN significantly. Conclusions SLEPG might improve insulin resistance in mature adipocyte.展开更多
文摘Aim To study the effect of Semen litchi effective part group （SLEPG） on insulin resistance in human adi- pocyte. Methods Primary adipocyte was obtained from fat tissue in liposuction patient and insulin resistance model was built up with dexamethasone induction. Gop-pod method was used to determine glucose in culture supematant and RT-PCR was used to assay RETN of treated cells. Results SLEPG increased the glucose consumption and ab- sorption in dexamethasone-induced insulin resistance in primary adipocyte culture. SLEC inhibited the mRNA expres- sion of RETN significantly. Conclusions SLEPG might improve insulin resistance in mature adipocyte.
