A study has been carried out of evaluating lipophilicity of some 1 1, 2, 4 triazole compounds by RP HPTLC. An equation that reasonably correlates partition coefficients( c lg P ) with R M 0 values for 23 \{1 1,2,4 tri...A study has been carried out of evaluating lipophilicity of some 1 1, 2, 4 triazole compounds by RP HPTLC. An equation that reasonably correlates partition coefficients( c lg P ) with R M 0 values for 23 \{1 1,2,4 triazole\} compounds was derived and its predictive capability was tested with five 1 1,2,4 triazole compounds. It has been found that RP HPTLC can be extensively applied to determining lipophilicity of \{1 1,2,4 triazole\} compounds.展开更多
文摘A study has been carried out of evaluating lipophilicity of some 1 1, 2, 4 triazole compounds by RP HPTLC. An equation that reasonably correlates partition coefficients( c lg P ) with R M 0 values for 23 \{1 1,2,4 triazole\} compounds was derived and its predictive capability was tested with five 1 1,2,4 triazole compounds. It has been found that RP HPTLC can be extensively applied to determining lipophilicity of \{1 1,2,4 triazole\} compounds.
