One-carbon unit transfer reaction of imidazolinium with 1,2-diaminobenzene has been studied with semi-empirical molecular orbital calculations, PM3. The result shows that there are two ways to complete this reaction b...One-carbon unit transfer reaction of imidazolinium with 1,2-diaminobenzene has been studied with semi-empirical molecular orbital calculations, PM3. The result shows that there are two ways to complete this reaction because the imidazolinium ring has two different breaking patterns. These two ways both have seven steps, including two proton-migrating steps that limit the rate of the reaction. The structures and energies of the intermediates and transition states have been calculated.展开更多
问题式学习(Problem Based Learning,简称PBL)是一种较先进的学习方式.文章以有机电合成的教学为案例,讨论了PBL法在精细有机合成单元反应教学中的应用.从学生学习反馈的结果可以看出,PBL法有利于培养学生理论联系实际、独立分析、团结...问题式学习(Problem Based Learning,简称PBL)是一种较先进的学习方式.文章以有机电合成的教学为案例,讨论了PBL法在精细有机合成单元反应教学中的应用.从学生学习反馈的结果可以看出,PBL法有利于培养学生理论联系实际、独立分析、团结协作、解决实际工程问题的能力.展开更多
文摘One-carbon unit transfer reaction of imidazolinium with 1,2-diaminobenzene has been studied with semi-empirical molecular orbital calculations, PM3. The result shows that there are two ways to complete this reaction because the imidazolinium ring has two different breaking patterns. These two ways both have seven steps, including two proton-migrating steps that limit the rate of the reaction. The structures and energies of the intermediates and transition states have been calculated.
