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抗抑郁药DOV216303的合成方法改进
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作者 刘侠 邵佳 +1 位作者 丁小东 杨劲松 《化学研究与应用》 CAS CSCD 北大核心 2010年第5期652-655,共4页
DOV216303 was synthesized via six procedures starting from 3,4-dichlorophenylacetic acid in an overall yield of 14%.The structure of the target compound was confirmed by 1H-NMR and MS.This improved method could avoid ... DOV216303 was synthesized via six procedures starting from 3,4-dichlorophenylacetic acid in an overall yield of 14%.The structure of the target compound was confirmed by 1H-NMR and MS.This improved method could avoid the usage of the expensive reagents,reduce the cost and increase the total yield. 展开更多
关键词 抗抑郁药 DOV216303 单胺递质抑制剂 合成
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