病例：患者,男,67岁。因“食道癌术后7年,头晕、乏力1周”入院。入院查体：体温（T）36.5℃,脉搏（P）78次/min,呼吸（R）20次/min,血压（BP）133/66 mm Hg。辅助检查（2015年7月15日）血常规示：白细胞2.00×109·L-1,红细胞2....病例：患者,男,67岁。因“食道癌术后7年,头晕、乏力1周”入院。入院查体：体温（T）36.5℃,脉搏（P）78次/min,呼吸（R）20次/min,血压（BP）133/66 mm Hg。辅助检查（2015年7月15日）血常规示：白细胞2.00×109·L-1,红细胞2.57×012·L-1,血红蛋白39.88 g·L-1。血生化示：白蛋白32.2 g·L-1,总蛋白59.4 g·L-1,钠134.5 mmol·L-1,钙LWmmol·L-1.凝血功能检查示：纤维蛋白原1.67g·L-1,分凝血活酶原时间52.0s血浆凝血酶时间24s。展开更多
患者女，49岁，因“颈部、腋下、腹股沟、腘窝、肘窝处出现色素沉着斑8年”，于2011年7月4日来我院就诊。8年前无明显诱因患者双侧腹股沟处出现大小不等黄褐色斑、斑丘疹，皮疹无明显痒痛不适，后颈部、双腋下、双肘窝、腘窝等处也渐出...患者女，49岁，因“颈部、腋下、腹股沟、腘窝、肘窝处出现色素沉着斑8年”，于2011年7月4日来我院就诊。8年前无明显诱因患者双侧腹股沟处出现大小不等黄褐色斑、斑丘疹，皮疹无明显痒痛不适，后颈部、双腋下、双肘窝、腘窝等处也渐出现类似皮疹，一直未正规就医。患者既往有高血压病史半年，口服尼莫地平控制良好。有子宫肌瘤病史10余年，平素月经量大，经期不规律，未行特殊治疗。否认其他内科疾病病史、长期服药史，无类似皮肤疾病家族史。育有一女，无类似病史。体格检查：一般情况良好，系统检查未见异常，浅表淋巴结未见肿大。皮肤科专科检查：右侧腹股沟见1．5 cm x1 cm黄褐色斑块，表面粗糙，呈疣状突起，无糜烂、渗液；颈部、双腋下、腘窝、肘窝多发大小不等黄褐色斑、斑丘疹，躯干部散在类似皮疹，颈部可见少许黑头粉刺样皮损；外阴部毛发稀疏，掌跖和指、趾甲无异常。辅助检查：血常规、凝血功能检查基本正常；心电图示窦性心律，ST段改变；胸部X线片、尿常规、性激素（血清促肾上腺皮质激素、促甲状腺激素、泌乳素、促卵泡刺激素、皮质醇、促黄体生成素、睾酮、雌二醇等）检测、肿瘤标志物检查无异常，甲苯胺红不加热血清试验（TRUST）阴性；腹部、盆腔B超检查示轻中度脂肪肝、胆囊结石、脾稍大、双肾小结石、腹膜后未见明显肿块，子宫肌层多发实性肿块（考虑子宫肌瘤）。皮损病理组织检查示右侧腹股沟斑块性皮损，符合脂溢性角化病；右大腿内侧黄褐色斑，病变符合皱褶部网状色素异常。患者确诊后自行放弃治疗。展开更多
Objective:To investigate the role of Hemocoagulase Injection used in the joint operation and the effect on the blood coagulable function.Methods:A total of 60 patients who undergoing joint operation in our hospital we...Objective:To investigate the role of Hemocoagulase Injection used in the joint operation and the effect on the blood coagulable function.Methods:A total of 60 patients who undergoing joint operation in our hospital were randomly divided into two groups.Experiment group(Group A,n=30)was injected with 2 U Hemocoagulase Injection in 5 min before anesthesia induction.The contrast group(Group B,n=30)was treated with 0.9%normal saline in 5 min before anesthesia induction.Then common anesthesia was given to the two groups of patients.The venous blood was withdrawn for blood routine examination,thrombelastography and coagulable function at the time of pre-inducement, end of operation,and in 6 and 12 h after operation.The change of thrombelastograph and coagulable state were monitored during the whole surgery.And the volume of transfusion and hemorrhage between two groups was contrasted. Results:After the use of Hemocoagulase Injection,the operative time was shortened obviously(P<0.05).The volumes hemorrhage and transfusion was obviously smaller in Group A than in Group B(P<0.01).Hemocoagulase Injection did not influence fibrinogen and thrombelastograph of Group A(P>0.05).Conclusion:Hemocoagulase Injection can reduce the volumes of hemorrhage and transfusion and not influence the coagulable function.It is worth using in the joint operation.展开更多
文摘患者女，49岁，因“颈部、腋下、腹股沟、腘窝、肘窝处出现色素沉着斑8年”，于2011年7月4日来我院就诊。8年前无明显诱因患者双侧腹股沟处出现大小不等黄褐色斑、斑丘疹，皮疹无明显痒痛不适，后颈部、双腋下、双肘窝、腘窝等处也渐出现类似皮疹，一直未正规就医。患者既往有高血压病史半年，口服尼莫地平控制良好。有子宫肌瘤病史10余年，平素月经量大，经期不规律，未行特殊治疗。否认其他内科疾病病史、长期服药史，无类似皮肤疾病家族史。育有一女，无类似病史。体格检查：一般情况良好，系统检查未见异常，浅表淋巴结未见肿大。皮肤科专科检查：右侧腹股沟见1．5 cm x1 cm黄褐色斑块，表面粗糙，呈疣状突起，无糜烂、渗液；颈部、双腋下、腘窝、肘窝多发大小不等黄褐色斑、斑丘疹，躯干部散在类似皮疹，颈部可见少许黑头粉刺样皮损；外阴部毛发稀疏，掌跖和指、趾甲无异常。辅助检查：血常规、凝血功能检查基本正常；心电图示窦性心律，ST段改变；胸部X线片、尿常规、性激素（血清促肾上腺皮质激素、促甲状腺激素、泌乳素、促卵泡刺激素、皮质醇、促黄体生成素、睾酮、雌二醇等）检测、肿瘤标志物检查无异常，甲苯胺红不加热血清试验（TRUST）阴性；腹部、盆腔B超检查示轻中度脂肪肝、胆囊结石、脾稍大、双肾小结石、腹膜后未见明显肿块，子宫肌层多发实性肿块（考虑子宫肌瘤）。皮损病理组织检查示右侧腹股沟斑块性皮损，符合脂溢性角化病；右大腿内侧黄褐色斑，病变符合皱褶部网状色素异常。患者确诊后自行放弃治疗。
文摘Objective:To investigate the role of Hemocoagulase Injection used in the joint operation and the effect on the blood coagulable function.Methods:A total of 60 patients who undergoing joint operation in our hospital were randomly divided into two groups.Experiment group(Group A,n=30)was injected with 2 U Hemocoagulase Injection in 5 min before anesthesia induction.The contrast group(Group B,n=30)was treated with 0.9%normal saline in 5 min before anesthesia induction.Then common anesthesia was given to the two groups of patients.The venous blood was withdrawn for blood routine examination,thrombelastography and coagulable function at the time of pre-inducement, end of operation,and in 6 and 12 h after operation.The change of thrombelastograph and coagulable state were monitored during the whole surgery.And the volume of transfusion and hemorrhage between two groups was contrasted. Results:After the use of Hemocoagulase Injection,the operative time was shortened obviously(P<0.05).The volumes hemorrhage and transfusion was obviously smaller in Group A than in Group B(P<0.01).Hemocoagulase Injection did not influence fibrinogen and thrombelastograph of Group A(P>0.05).Conclusion:Hemocoagulase Injection can reduce the volumes of hemorrhage and transfusion and not influence the coagulable function.It is worth using in the joint operation.
