In a thin HCl medium,RRS intensities of an alone CS or acidic triphenylmethane dye (TPMD) are very week. However,when TPMD reacts with a CS to form an ion-associate,the RRS intensity is enhanced greatly and a new RRS ...In a thin HCl medium,RRS intensities of an alone CS or acidic triphenylmethane dye (TPMD) are very week. However,when TPMD reacts with a CS to form an ion-associate,the RRS intensity is enhanced greatly and a new RRS spectrum appears. The spectral characteristics of the RRS for the ion-associates and the optimum conditions for the reactions are investigated. The intensity of RRS is directly proportional to the mass concentration of CS in the range of 0—3.5 or 0—5.0 μg/mL. The method has a high sensitivity for the determination of CS,their detection limits are between 3.1 and 9.8 ng/mL depending on the different CS. In this case,most metal and non-metal ions do not interfere,so that the method has a good selectivity. Therefore,a sensitive,selective,simple and rapid method for the determination of CS by RRS is developed. [WT5HZ]展开更多
In 0.12 mol/L hydrochloric acid and nitric acid media,mitoxantrone interacted with molybdate to form an ion-association complex,which can result in the significant enhancement of RRS intensity.The(maximum) scattering ...In 0.12 mol/L hydrochloric acid and nitric acid media,mitoxantrone interacted with molybdate to form an ion-association complex,which can result in the significant enhancement of RRS intensity.The(maximum) scattering wavelengths were 365 nm for RRS and scattering intensities are proportional to the concentration of mitoxantrone,which can be applied to the determination of mitoxantrone.The detection limits are(6 ng/mL) in nitric acid and 8 ng/mL in hydrochloric acid respectively.Because there are not such interactions between anthracycline anticancer drugs such as daunorubicin and epirubicin with molybdate,mitoxantrone can be determined selectively with other anthracycline anticancer drugs existing.The optimum experiment condition,affecting factor and the effect of coexisting substance were investigated in the paper.The application to the determination of mitoxantrone in serum and urine by RRS were not only sensitive but also simple and ra-pid.In addition,the interaction mechanism was discussed.展开更多
文摘In a thin HCl medium,RRS intensities of an alone CS or acidic triphenylmethane dye (TPMD) are very week. However,when TPMD reacts with a CS to form an ion-associate,the RRS intensity is enhanced greatly and a new RRS spectrum appears. The spectral characteristics of the RRS for the ion-associates and the optimum conditions for the reactions are investigated. The intensity of RRS is directly proportional to the mass concentration of CS in the range of 0—3.5 or 0—5.0 μg/mL. The method has a high sensitivity for the determination of CS,their detection limits are between 3.1 and 9.8 ng/mL depending on the different CS. In this case,most metal and non-metal ions do not interfere,so that the method has a good selectivity. Therefore,a sensitive,selective,simple and rapid method for the determination of CS by RRS is developed. [WT5HZ]
文摘In 0.12 mol/L hydrochloric acid and nitric acid media,mitoxantrone interacted with molybdate to form an ion-association complex,which can result in the significant enhancement of RRS intensity.The(maximum) scattering wavelengths were 365 nm for RRS and scattering intensities are proportional to the concentration of mitoxantrone,which can be applied to the determination of mitoxantrone.The detection limits are(6 ng/mL) in nitric acid and 8 ng/mL in hydrochloric acid respectively.Because there are not such interactions between anthracycline anticancer drugs such as daunorubicin and epirubicin with molybdate,mitoxantrone can be determined selectively with other anthracycline anticancer drugs existing.The optimum experiment condition,affecting factor and the effect of coexisting substance were investigated in the paper.The application to the determination of mitoxantrone in serum and urine by RRS were not only sensitive but also simple and ra-pid.In addition,the interaction mechanism was discussed.
