The motion of the fins and control surfaces of underwater vehicles in a fluid is an interesting and challenging research subject.Typically the effect of fin oscillations on the fluid flow around such a body is highly ...The motion of the fins and control surfaces of underwater vehicles in a fluid is an interesting and challenging research subject.Typically the effect of fin oscillations on the fluid flow around such a body is highly unsteady, generating vortices and requiring detailed analysis of fluid-structure interactions.An understanding of the complexities of such flows is of interest to engineers developing vehicles capable of high dynamic performance in their propulsion and maneuvering.In the present study, a CFD based RANS simulation of a 3-D fin body moving in a viscous fluid was developed.It investigated hydrodynamic performance by evaluating the hydrodynamic coefficients (lift, drag and moment) at two different oscillating frequencies.A parametric analysis of the factors that affect the hydrodynamic performance of the fin body was done, along with a comparison of results from experiments.The results of the simulation were found in close agreement with experimental results and this validated the simulation as an effective tool for evaluation of the unsteady hydrodynamic coefficients of 3-D fins.This work can be further be used for analysis of the stability and maneuverability of fin actuated underwater vehicles.展开更多
In this paper, the acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure are investigated. The similitude conditions and relations between the similitude model and ...In this paper, the acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure are investigated. The similitude conditions and relations between the similitude model and its prototype were studied in the references. This paper investigates the acoustic scale effects for the similitude model, which are influenced by loss factor, shear and rotatory inertia. At the same time, the boundary effects which are influenced by surface sound reflection are investigated in the experiment of similitude model. The results show that the acoustic scale effects may be controlled with model designing, the boundary effects can be controlled with experimental designing between the similitude model and its prototype.展开更多
This paper presents an improved unstructured grid immersed boundary method.The advantages of both immersed boundary method and body fitted grids which are generated by unstructured grid technology are used to enhance ...This paper presents an improved unstructured grid immersed boundary method.The advantages of both immersed boundary method and body fitted grids which are generated by unstructured grid technology are used to enhance the computation efficiency of fluid structure interaction in complex domain.The Navier-Stokes equation was discretized spacially with collocated finite volume method and Euler implicit method in time domain.The rigid body motion was simulated by immersed boundary method in which the fluid and rigid body interface interaction was dealt with VOS(volume of solid) method.A new VOS calculation method based on graph was presented in which both immersed boundary points and cross points were collected in arbitrary order to form a graph.The method is verified with flow past oscillating cylinder.展开更多
In this paper, an investigation into the propagation of far field explosion waves in water and their effects on nearby structures are carried out. For the far field structure, the motion of the fluid surrounding the s...In this paper, an investigation into the propagation of far field explosion waves in water and their effects on nearby structures are carried out. For the far field structure, the motion of the fluid surrounding the structure may be assumed small, allowing linearization of the governing fluid equations. A complete analysis of the problem must involve simultaneous solution of the dynamic response of the structure and the propagation of explosion wave in the surrounding fluid. In this study, a dynamic adaptive finite element procedure is proposed. Its application to the solution of a 2D fluid-structure interaction is investigated in the time domain. The research includes:a) calculation of the far-field scatter wave due to underwater explosion including solution of the time-depended acoustic wave equation, b) fluid-structure interaction analysis using coupled Euler-Lagrangian approach, and c) adaptive finite element procedures employing error estimates, and re-meshing. The temporal mesh adaptation is achieved by local regeneration of the grid using a time-dependent error indicator based on curvature of pressure function. As a result, the overall response is better predicted by a moving mesh than an equivalent uniform mesh. In addition, the cost of computation for large problems is reduced while the accuracy is improved.展开更多
There is a large class of problems in the field of fluid structure interaction where higher-order boundary conditions arise for a second-order partial differential equation. Various methods are being used to tackle th...There is a large class of problems in the field of fluid structure interaction where higher-order boundary conditions arise for a second-order partial differential equation. Various methods are being used to tackle these kind of mixed boundary-value problems associated with the Laplace’s equation (or Helmholtz equation) arising in the study of waves propagating through solids or fluids. One of the widely used methods in wave structure interaction is the multipole expansion method. This expansion involves a general combination of a regular wave, a wave source, a wave dipole and a regular wave-free part. The wave-free part can be further expanded in terms of wave-free multipoles which are termed as wave-free potentials. These are singular solutions of Laplace’s equation or two-dimensional Helmholz equation. Construction of these wave-free potentials and multipoles are presented here in a systematic manner for a number of situations such as two-dimensional non-oblique and oblique waves, three dimensional waves in two-layer fluid with free surface condition with higher order partial derivative are considered. In particular, these are obtained taking into account of the effect of the presence of surface tension at the free surface and also in the presence of an ice-cover modelled as a thin elastic plate. Also for limiting case, it can be shown that the multipoles and wave-free potential functions go over to the single layer multipoles and wave-free potential.展开更多
Hydroelastic behavior of an elastic wedge impacting on calm water surface was investigated. A partitioned approach by coupling finite difference method (FDM) and finite element method (FEM) was developed to analyz...Hydroelastic behavior of an elastic wedge impacting on calm water surface was investigated. A partitioned approach by coupling finite difference method (FDM) and finite element method (FEM) was developed to analyze the fluid structure interaction (FSI) problem. The FDM, in which the Constraint Interpolation Profile (CIP) method was applied, was used for solving the flow field in a fixed regular Cartesian grid system. Free surface was captured by the Tangent of Hyperbola for Interface Capturing with Slope Weighting (THINC/SW) scheme. The FEM was applied for calculating the structural deformation. A volume weighted method, which was based on the immersed boundary (IB) method, was adopted for coupling the FDM and the FEM together. An elastic wedge water entry problem was calculated by the coupled FDM-FEM method. Also a comparison between the current numerical results and the published results indicate that the coupled FDM-FEM method has reasonably good accuracy in predicting the impact force.展开更多
Objective: To explore the correlation between structure domains and functions of chemokine receptor CXCR4. Methods: After the establishment of wild type chemokine.receptor CXCR4 and CXCR2 expressing cell lines, 5 CXCR...Objective: To explore the correlation between structure domains and functions of chemokine receptor CXCR4. Methods: After the establishment of wild type chemokine.receptor CXCR4 and CXCR2 expressing cell lines, 5 CXCR4/CXCR2 chimeras, 2 CXCR4 mutants were stably expressed on CHO cell line. Binding activities of all variants with the ligand, recombinant human SDF-1β, signal transduction ability after stimulation and their function as coreceptor for HIV-1 were studied with ligand-binding assay, Cytosensor/ microphysiometry and cell-cell reporter gene fusion assay. Results: Among all 7 changed CXCR4 receptors, 3 chimeras (2444a, 4442, 4122), and 1 mutant (CXCR4-Tr) bond with SDF-1β in varying degrees, of which only 2444a totally and CXCR4-Tr partially maintain signaling. All changed receptors except for 4222 could act as coreceptors for HIV-1 (LAI) in varying degrees. Conclusion: Several structure domains of CXCR4 are involved in the binding with SDF-1β, among which, N-terminal extracellular domain has high affinity of binding with SDF-1β, and the 3rd extracellular loop contributes to the binding, too. Although the C-terminal in-tracellular domain has no association with the maintenance of the overall structure of the receptor and ligand binding capability, the signaling is decreased when this domain is truncated. For CXCR4 signaling, not only is the conserved motif DRY box needed, but also the characterized conformation of the whole molecule must be formed when activation is required. There are some overlaps between SDF-1β binding domains and coreceptor function domains in molecular structure of CXCR4.展开更多
Sloshing phenomenon in the liquid cargo carriers has caught the attention of researchers as the interaction between the sloshing waves and structure is one of the key point and difficulty in the study of sloshing.In t...Sloshing phenomenon in the liquid cargo carriers has caught the attention of researchers as the interaction between the sloshing waves and structure is one of the key point and difficulty in the study of sloshing.In this paper,we captured the free surface with a volume of fluid(VOF) method and then calculated the motions and responses of the structure by adopting the Reynolds-averaged Navier-Stokes(RANS) equations for the whole fluid domain.With the use of user defined functions(UDF) in Fluent,the interaction between fluid and structure was then simulated.As a reasonable simplification,the authors studied the response of a single cantilever in a tank under sloshing loads;Further study should pay more attention to the mechanisms of interaction between sloshing waves and elastic structures.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No.50879014
文摘The motion of the fins and control surfaces of underwater vehicles in a fluid is an interesting and challenging research subject.Typically the effect of fin oscillations on the fluid flow around such a body is highly unsteady, generating vortices and requiring detailed analysis of fluid-structure interactions.An understanding of the complexities of such flows is of interest to engineers developing vehicles capable of high dynamic performance in their propulsion and maneuvering.In the present study, a CFD based RANS simulation of a 3-D fin body moving in a viscous fluid was developed.It investigated hydrodynamic performance by evaluating the hydrodynamic coefficients (lift, drag and moment) at two different oscillating frequencies.A parametric analysis of the factors that affect the hydrodynamic performance of the fin body was done, along with a comparison of results from experiments.The results of the simulation were found in close agreement with experimental results and this validated the simulation as an effective tool for evaluation of the unsteady hydrodynamic coefficients of 3-D fins.This work can be further be used for analysis of the stability and maneuverability of fin actuated underwater vehicles.
基金Supported by Specialized Research Fund for the Doctoral Program of Higher Education Under Grant No. 20030317013.
文摘In this paper, the acoustic scale effects and boundary effects for the similitude model of underwater complex shell-structure are investigated. The similitude conditions and relations between the similitude model and its prototype were studied in the references. This paper investigates the acoustic scale effects for the similitude model, which are influenced by loss factor, shear and rotatory inertia. At the same time, the boundary effects which are influenced by surface sound reflection are investigated in the experiment of similitude model. The results show that the acoustic scale effects may be controlled with model designing, the boundary effects can be controlled with experimental designing between the similitude model and its prototype.
文摘This paper presents an improved unstructured grid immersed boundary method.The advantages of both immersed boundary method and body fitted grids which are generated by unstructured grid technology are used to enhance the computation efficiency of fluid structure interaction in complex domain.The Navier-Stokes equation was discretized spacially with collocated finite volume method and Euler implicit method in time domain.The rigid body motion was simulated by immersed boundary method in which the fluid and rigid body interface interaction was dealt with VOS(volume of solid) method.A new VOS calculation method based on graph was presented in which both immersed boundary points and cross points were collected in arbitrary order to form a graph.The method is verified with flow past oscillating cylinder.
文摘In this paper, an investigation into the propagation of far field explosion waves in water and their effects on nearby structures are carried out. For the far field structure, the motion of the fluid surrounding the structure may be assumed small, allowing linearization of the governing fluid equations. A complete analysis of the problem must involve simultaneous solution of the dynamic response of the structure and the propagation of explosion wave in the surrounding fluid. In this study, a dynamic adaptive finite element procedure is proposed. Its application to the solution of a 2D fluid-structure interaction is investigated in the time domain. The research includes:a) calculation of the far-field scatter wave due to underwater explosion including solution of the time-depended acoustic wave equation, b) fluid-structure interaction analysis using coupled Euler-Lagrangian approach, and c) adaptive finite element procedures employing error estimates, and re-meshing. The temporal mesh adaptation is achieved by local regeneration of the grid using a time-dependent error indicator based on curvature of pressure function. As a result, the overall response is better predicted by a moving mesh than an equivalent uniform mesh. In addition, the cost of computation for large problems is reduced while the accuracy is improved.
文摘There is a large class of problems in the field of fluid structure interaction where higher-order boundary conditions arise for a second-order partial differential equation. Various methods are being used to tackle these kind of mixed boundary-value problems associated with the Laplace’s equation (or Helmholtz equation) arising in the study of waves propagating through solids or fluids. One of the widely used methods in wave structure interaction is the multipole expansion method. This expansion involves a general combination of a regular wave, a wave source, a wave dipole and a regular wave-free part. The wave-free part can be further expanded in terms of wave-free multipoles which are termed as wave-free potentials. These are singular solutions of Laplace’s equation or two-dimensional Helmholz equation. Construction of these wave-free potentials and multipoles are presented here in a systematic manner for a number of situations such as two-dimensional non-oblique and oblique waves, three dimensional waves in two-layer fluid with free surface condition with higher order partial derivative are considered. In particular, these are obtained taking into account of the effect of the presence of surface tension at the free surface and also in the presence of an ice-cover modelled as a thin elastic plate. Also for limiting case, it can be shown that the multipoles and wave-free potential functions go over to the single layer multipoles and wave-free potential.
基金the support of Grants-in-Aid for Scientific Research (B), MEXT (No.24360358)
文摘Hydroelastic behavior of an elastic wedge impacting on calm water surface was investigated. A partitioned approach by coupling finite difference method (FDM) and finite element method (FEM) was developed to analyze the fluid structure interaction (FSI) problem. The FDM, in which the Constraint Interpolation Profile (CIP) method was applied, was used for solving the flow field in a fixed regular Cartesian grid system. Free surface was captured by the Tangent of Hyperbola for Interface Capturing with Slope Weighting (THINC/SW) scheme. The FEM was applied for calculating the structural deformation. A volume weighted method, which was based on the immersed boundary (IB) method, was adopted for coupling the FDM and the FEM together. An elastic wedge water entry problem was calculated by the coupled FDM-FEM method. Also a comparison between the current numerical results and the published results indicate that the coupled FDM-FEM method has reasonably good accuracy in predicting the impact force.
文摘Objective: To explore the correlation between structure domains and functions of chemokine receptor CXCR4. Methods: After the establishment of wild type chemokine.receptor CXCR4 and CXCR2 expressing cell lines, 5 CXCR4/CXCR2 chimeras, 2 CXCR4 mutants were stably expressed on CHO cell line. Binding activities of all variants with the ligand, recombinant human SDF-1β, signal transduction ability after stimulation and their function as coreceptor for HIV-1 were studied with ligand-binding assay, Cytosensor/ microphysiometry and cell-cell reporter gene fusion assay. Results: Among all 7 changed CXCR4 receptors, 3 chimeras (2444a, 4442, 4122), and 1 mutant (CXCR4-Tr) bond with SDF-1β in varying degrees, of which only 2444a totally and CXCR4-Tr partially maintain signaling. All changed receptors except for 4222 could act as coreceptors for HIV-1 (LAI) in varying degrees. Conclusion: Several structure domains of CXCR4 are involved in the binding with SDF-1β, among which, N-terminal extracellular domain has high affinity of binding with SDF-1β, and the 3rd extracellular loop contributes to the binding, too. Although the C-terminal in-tracellular domain has no association with the maintenance of the overall structure of the receptor and ligand binding capability, the signaling is decreased when this domain is truncated. For CXCR4 signaling, not only is the conserved motif DRY box needed, but also the characterized conformation of the whole molecule must be formed when activation is required. There are some overlaps between SDF-1β binding domains and coreceptor function domains in molecular structure of CXCR4.
基金Supported by the National Natural Science Foundation of China under the Grant No.10472032,50879030
文摘Sloshing phenomenon in the liquid cargo carriers has caught the attention of researchers as the interaction between the sloshing waves and structure is one of the key point and difficulty in the study of sloshing.In this paper,we captured the free surface with a volume of fluid(VOF) method and then calculated the motions and responses of the structure by adopting the Reynolds-averaged Navier-Stokes(RANS) equations for the whole fluid domain.With the use of user defined functions(UDF) in Fluent,the interaction between fluid and structure was then simulated.As a reasonable simplification,the authors studied the response of a single cantilever in a tank under sloshing loads;Further study should pay more attention to the mechanisms of interaction between sloshing waves and elastic structures.