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采用吸宫和电凝方法建立小鼠子宫内膜损伤模型的比较 被引量:5
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作者 王晏鹏 黄琼晓 +1 位作者 徐盛 舒静 《浙江大学学报(医学版)》 CAS CSCD 北大核心 2017年第2期186-191,共6页
日的:比较吸宫和电凝两种方法造成小鼠子宫内膜损伤模型的特点。方法:吸宫组采用自制20 G针头插入ICR小鼠一侧宫腔,以0.05 MPa负压全面吸宫1周;电凝组采用自制单极电针以0.5 W功率迅速电凝损伤子宫腔。均以对侧子宫为对照,对照仅插入针... 日的:比较吸宫和电凝两种方法造成小鼠子宫内膜损伤模型的特点。方法:吸宫组采用自制20 G针头插入ICR小鼠一侧宫腔,以0.05 MPa负压全面吸宫1周;电凝组采用自制单极电针以0.5 W功率迅速电凝损伤子宫腔。均以对侧子宫为对照,对照仅插入针头或电针后退出。比较平均手术时间、术后单层子宫内膜厚度、妊娠4 d子宫内膜容受性相关因子的表达情况、妊娠10 d胎鼠数差别。其中HE染色观察子宫内膜组织形态学改变,蛋白质印迹法检测子宫内膜白血病抑制因子和抑瘤素M的表达。结果:吸宫组平均手术时间(10.2±1.3)min,电凝组平均手术时间(10.1±1.5)min,差异无统计学意义(P>0.05)。吸宫组损伤侧宫腔无封闭现象,电凝组有2只小鼠存在宫腔局部封闭、远段积水。损伤侧子宫内膜厚度吸宫组(96.1±13.2)μm、电凝组(88.9±16.8)μm,均比对照侧子宫减小(均P<0.01)。损伤侧子宫内膜白血病抑制因子和抑瘤素M的表达吸宫组高于电凝组,但两组损伤侧表达均低于对照侧(均P<0.01)。吸宫组损伤侧平均胎鼠数目(4.2±0.9)只,电凝组损伤侧平均胎鼠数目(3.9±1.7)只,均较对照侧减少(均P<0.01)。电凝组损伤侧还可见胎鼠死亡现象。结论:吸宫和电凝均可造成小鼠子宫内膜损伤,导致子宫内膜容受性下降和生育力受损。电凝损伤更符合重度宫腔粘连特征,而吸宫损伤可能更适用于轻中度宫腔粘连研究。 展开更多
关键词 电凝术 流产 人工/方法 子宫疾病 黏连 子宫内膜 疾病模型 动物
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Study and application of monitoring plane displacement of a similarity model based on time-series images 被引量:5
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作者 Xu Jiankun Wang Enyuan +1 位作者 Li Zhonghui Wang Chao 《Mining Science and Technology》 EI CAS 2011年第4期501-505,共5页
In order to compensate for the deficiency of present methods of monitoring plane displacement in similarity model tests,such as inadequate real-time monitoring and more manual intervention,an effective monitoring meth... In order to compensate for the deficiency of present methods of monitoring plane displacement in similarity model tests,such as inadequate real-time monitoring and more manual intervention,an effective monitoring method was proposed in this study,and the major steps of the monitoring method include:firstly,time-series images of the similarity model in the test were obtained by a camera,and secondly,measuring points marked as artificial targets were automatically tracked and recognized from time-series images.Finally,the real-time plane displacement field was calculated by the fixed magnification between objects and images under the specific conditions.And then the application device of the method was designed and tested.At the same time,a sub-pixel location method and a distortion error model were used to improve the measuring accuracy.The results indicate that this method may record the entire test,especially the detailed non-uniform deformation and sudden deformation.Compared with traditional methods this method has a number of advantages,such as greater measurement accuracy and reliability,less manual intervention,higher automation,strong practical properties,much more measurement information and so on. 展开更多
关键词 Plane displacement monitoring Similarity model test Time-series images Displacement measurement
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Artificial neural network approach for rheological characteristics of coal-water slurry using microwave pre-treatment 被引量:4
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作者 B.K.Sahoo S.De B.C.Meikap 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2017年第2期379-386,共8页
Detailed experimental investigations were carried out for microwave pre-treatment of high ash Indian coal at high power level(900 W) in microwave oven. The microwave exposure times were fixed at60 s and 120 s. A rheol... Detailed experimental investigations were carried out for microwave pre-treatment of high ash Indian coal at high power level(900 W) in microwave oven. The microwave exposure times were fixed at60 s and 120 s. A rheology characteristic for microwave pre-treatment of coal-water slurry(CWS) was performed in an online Bohlin viscometer. The non-Newtonian character of the slurry follows the rheological model of Ostwald de Waele. The values of n and k vary from 0.31 to 0.64 and 0.19 to 0.81 Pa·sn,respectively. This paper presents an artificial neural network(ANN) model to predict the effects of operational parameters on apparent viscosity of CWS. A 4-2-1 topology with Levenberg-Marquardt training algorithm(trainlm) was selected as the controlled ANN. Mean squared error(MSE) of 0.002 and coefficient of multiple determinations(R^2) of 0.99 were obtained for the outperforming model. The promising values of correlation coefficient further confirm the robustness and satisfactory performance of the proposed ANN model. 展开更多
关键词 Microwave pre-treatment Coal-water slurry Apparent viscosity Artificial neural network Back propagation algorithm
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Linkage intensity learning approach with genetic algorithm for causality diagram
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作者 WANG Cheng-liang CHEN Juan-juan 《Journal of Chongqing University》 CAS 2007年第2期135-140,共6页
The causality diagram theory, which adopts graphical expression of knowledge and direct intensity of causality, overcomes some shortages in belief network and has evolved into a mixed causality diagram methodology for... The causality diagram theory, which adopts graphical expression of knowledge and direct intensity of causality, overcomes some shortages in belief network and has evolved into a mixed causality diagram methodology for discrete and continuous variable. But to give linkage intensity of causality diagram is difficult, particularly in many working conditions in which sampling data are limited or noisy. The classic learning algorithm is hard to be adopted. We used genetic algorithm to learn linkage intensity from limited data. The simulation results demonstrate that this algorithm is more suitable than the classic algorithm in the condition of sample shortage such as space shuttle’s fault diagnoisis. 展开更多
关键词 causality diagram genetic algorithm linkage Intensity parameter learning
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Multi-agent reinforcement learning using modular neural network Q-learning algorithms
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作者 杨银贤 《Journal of Chongqing University》 CAS 2005年第1期50-54,共5页
Reinforcement learning is an excellent approach which is used in artificial intelligence,automatic control, etc. However, ordinary reinforcement learning algorithm, such as Q-learning with lookup table cannot cope wit... Reinforcement learning is an excellent approach which is used in artificial intelligence,automatic control, etc. However, ordinary reinforcement learning algorithm, such as Q-learning with lookup table cannot cope with extremely complex and dynamic environment due to the huge state space. To reduce the state space, modular neural network Q-learning algorithm is proposed, which combines Q-learning algorithm with neural network and module method. Forward feedback neural network, Elman neural network and radius-basis neural network are separately employed to construct such algorithm. It is revealed that Elman neural network Q-learning algorithm has the best performance under the condition that the same neural network training method, i.e. gradient descent error back-propagation algorithm is applied. 展开更多
关键词 reinforcement learning Q-LEARNING neural network artificial intelligence
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A Method of Identifying Electromagnetic Radiation Sources by Using Support Vector Machines 被引量:2
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作者 石丹 高攸纲 《China Communications》 SCIE CSCD 2013年第7期36-43,共8页
Electromagnetic Radiation Source Identification(ERSI) is a key technology that is widely used in military and radiation management and in electromagnetic interference diagnostics.The discriminative capability of machi... Electromagnetic Radiation Source Identification(ERSI) is a key technology that is widely used in military and radiation management and in electromagnetic interference diagnostics.The discriminative capability of machine learning methods has recently been used for facilitating ERSI.This paper presents a new approach to improve ERSI by adopting support vector machines,which are proven to be effective tools in pattern classification and regression,on the basis of the spatial distribution of electromagnetic radiation sources.Spatial information is converted from 3D cubes to 1D vectors with subscripts as inputs in order to simplify the model.The model is trained with 187 500 data sets in order to enable it to identify the types of radiation source types with an accuracy of up to 99.9%.The influence of parameters(e.g.,penalty parameter,reflection and noise from the ambient environment,and the scaling method for the input data) are discussed.The proposed method has good performance in noisy and reverberant environment.It has an identification accuracy of 82.15% when the signal-to-noise ratio is 20 dB.The proposed method has better accuracy in a noisy environment than artificial neural networks.Given that each Electromagnetic(EM) source has unique spatial characteristics,this method can be used for EM source identification and EM interference diagnostics. 展开更多
关键词 support vector machines electro- magnetic radiation sources spatial characteistics IDENTIFICATION
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