The complexes of dimethylcyclopentadienyl dichlorotitanium(Ⅳ)and salicytic acid,sulfhydryl salicylic acid,5-nitrosalicylic acid,3,5-dinitro salicylic acid have been prepared in aqueous-phase.The structures have been ...The complexes of dimethylcyclopentadienyl dichlorotitanium(Ⅳ)and salicytic acid,sulfhydryl salicylic acid,5-nitrosalicylic acid,3,5-dinitro salicylic acid have been prepared in aqueous-phase.The structures have been determined by elemental analysis,IR and 1HNMR spectra. It’s approved that (MeCp) 2TiCl 2-acetylacetone complex reacts with sodium of salicylic acid or substituted derivatives in aqueous-phase,and the results depend on the pH of salicylate solution,concentration and temperature.The best condition of the preparation of dimethylcyclopentadienyl salicylatotitanium(Ⅳ)complexes is that:the molar ration of (MeCp) 2TiCl 2 and substituted salicylic acid is 1:1;the pH being controlled in 6 0-7 5.The disalicylato derivatives of dimethylcyclopentadienyl titanium(Ⅳ)are whereby where by (MeCp) 2TiCl 2 and substituted salicylic acid are close in the molar ratio of 1 to 2,and the pH is 3.5-4.5.In all the preparations,the temperature is at 0℃ and the molar concentration of substituted salicylic acid is 0.04 mol/L.The mechanism of the reaction was also discussed.展开更多
The interaction between titanocene glycine complex and DNA has been investigat-ed by UV-Vis spectra and fluorescence probe method. The results suggest that the complex forms an irreversible adduct with DNA in molar ra...The interaction between titanocene glycine complex and DNA has been investigat-ed by UV-Vis spectra and fluorescence probe method. The results suggest that the complex forms an irreversible adduct with DNA in molar ratio 1:1, and induces the comformation changes of DNA at high ratio of the complex to DNA,leading to the disruption of DNA du-plexical structure.展开更多
Four titanocene complexes have been prepared by reacting Cp 2TiCl 2 with substituted phthalic acid in water or in CH 2Cl 2/H 2O medium.The complexes were characterized by elemental analysis,IR and 1HNMR spectra.The re...Four titanocene complexes have been prepared by reacting Cp 2TiCl 2 with substituted phthalic acid in water or in CH 2Cl 2/H 2O medium.The complexes were characterized by elemental analysis,IR and 1HNMR spectra.The results suggest that the complexes have two kinds of structure A and B.When reacted in water,the complexes Ⅰ and Ⅳ are obtained.The complexes Ⅱ,Ⅲ and Ⅳ are obtained in two phases.展开更多
Five titanocene amino acid complexes, Cp 2Ti(O 2CCH 2NHC 6H 4R) 2 (R=H, p Cl, p OC 2H 5, m CH 3, m Cl), have been prepared in a two phase system(CHCl 3/H 2O), by reacting Cp 2TiCl 2 with corresponding amino acids (RC ...Five titanocene amino acid complexes, Cp 2Ti(O 2CCH 2NHC 6H 4R) 2 (R=H, p Cl, p OC 2H 5, m CH 3, m Cl), have been prepared in a two phase system(CHCl 3/H 2O), by reacting Cp 2TiCl 2 with corresponding amino acids (RC 6H 4NHCH 2COOH ). The complexes were characterized by elemental analysis, IR and 1H NMR spectra. The results show that the carboxyl oxygen is bound to Ti to form two molecular amino acid complex and the carboxyl itself in amino acid acts as monodentate ligand. In comparison with synthesis in aqueous or anhydrolytic medium, the reaction in two phase medium appears more simply and conveniently, with yield being higher.展开更多
An interfacial method of synthesizing the complexes of titanocene with substituted salicylic acid is reported. The complexes are characterized by elemental analysis, IR and 1H NMR spectra. According to the spectroscop...An interfacial method of synthesizing the complexes of titanocene with substituted salicylic acid is reported. The complexes are characterized by elemental analysis, IR and 1H NMR spectra. According to the spectroscopic data, it is suggested that the hydroxyl and carboxyl oxygen in substituted salicylic acid are bound to Ti of titanocene forming hexacyclic compound.展开更多
文摘The complexes of dimethylcyclopentadienyl dichlorotitanium(Ⅳ)and salicytic acid,sulfhydryl salicylic acid,5-nitrosalicylic acid,3,5-dinitro salicylic acid have been prepared in aqueous-phase.The structures have been determined by elemental analysis,IR and 1HNMR spectra. It’s approved that (MeCp) 2TiCl 2-acetylacetone complex reacts with sodium of salicylic acid or substituted derivatives in aqueous-phase,and the results depend on the pH of salicylate solution,concentration and temperature.The best condition of the preparation of dimethylcyclopentadienyl salicylatotitanium(Ⅳ)complexes is that:the molar ration of (MeCp) 2TiCl 2 and substituted salicylic acid is 1:1;the pH being controlled in 6 0-7 5.The disalicylato derivatives of dimethylcyclopentadienyl titanium(Ⅳ)are whereby where by (MeCp) 2TiCl 2 and substituted salicylic acid are close in the molar ratio of 1 to 2,and the pH is 3.5-4.5.In all the preparations,the temperature is at 0℃ and the molar concentration of substituted salicylic acid is 0.04 mol/L.The mechanism of the reaction was also discussed.
文摘The interaction between titanocene glycine complex and DNA has been investigat-ed by UV-Vis spectra and fluorescence probe method. The results suggest that the complex forms an irreversible adduct with DNA in molar ratio 1:1, and induces the comformation changes of DNA at high ratio of the complex to DNA,leading to the disruption of DNA du-plexical structure.
文摘Four titanocene complexes have been prepared by reacting Cp 2TiCl 2 with substituted phthalic acid in water or in CH 2Cl 2/H 2O medium.The complexes were characterized by elemental analysis,IR and 1HNMR spectra.The results suggest that the complexes have two kinds of structure A and B.When reacted in water,the complexes Ⅰ and Ⅳ are obtained.The complexes Ⅱ,Ⅲ and Ⅳ are obtained in two phases.
文摘Five titanocene amino acid complexes, Cp 2Ti(O 2CCH 2NHC 6H 4R) 2 (R=H, p Cl, p OC 2H 5, m CH 3, m Cl), have been prepared in a two phase system(CHCl 3/H 2O), by reacting Cp 2TiCl 2 with corresponding amino acids (RC 6H 4NHCH 2COOH ). The complexes were characterized by elemental analysis, IR and 1H NMR spectra. The results show that the carboxyl oxygen is bound to Ti to form two molecular amino acid complex and the carboxyl itself in amino acid acts as monodentate ligand. In comparison with synthesis in aqueous or anhydrolytic medium, the reaction in two phase medium appears more simply and conveniently, with yield being higher.
文摘An interfacial method of synthesizing the complexes of titanocene with substituted salicylic acid is reported. The complexes are characterized by elemental analysis, IR and 1H NMR spectra. According to the spectroscopic data, it is suggested that the hydroxyl and carboxyl oxygen in substituted salicylic acid are bound to Ti of titanocene forming hexacyclic compound.
