A peptides migration model based on the principle of mechanics is presented in capillary zone electrophoresis (CZE). It is shown that the migration that the (tr) is a function of electric (Q), relative molecular mass ...A peptides migration model based on the principle of mechanics is presented in capillary zone electrophoresis (CZE). It is shown that the migration that the (tr) is a function of electric (Q), relative molecular mass (Mr), conformation parameter (Rc) of peptides and electrophoretic condition parameter(A). The conformation parameter is introduced to characterize multifarious shapes owing to the complex conlormation and the various kinds of macromolecules, where Rc≥1/3. The parameters A and Rc can be obtained from experimental data. The times of migration of the nine standard peptides were measured in pH 2.5buffer on different electrophoretic conditions in CZE. The experimental results agreed well with the theoretical prediction.展开更多
Identifying risk factors for road traffic injuries can be considered one of the main priorities of transportation agencies. More than 12,000 fatal work zone crashes were reported between 2000 and 2013. Despite recent ...Identifying risk factors for road traffic injuries can be considered one of the main priorities of transportation agencies. More than 12,000 fatal work zone crashes were reported between 2000 and 2013. Despite recent efforts to improve work zone safety, the frequency and severity of work zone crashes are still a big concern for transportation agencies. Although many studies have been conducted on different work zone safety-related issues, there is a lack of studies that investigate the effect of adverse weather conditions on work zone crash severity. This paper utilizes probit–classification tree, a relatively recent and promising combination of machine learning technique and conventional parametric model, to identify factors affecting work zone crash severity in adverse weather conditions using 8 years of work zone weatherrelated crashes (2006–2013) in Washington State. The key strength of this technique lies in its capability to alleviate the shortcomings of both parametric and nonparametric models. The results showed that both presence of traffic control device and lighting conditions are significant interacting variables in the developed complementary crash severity model for work zone weather-related crashes. Therefore, transportation agencies and contractors need to invest more in lighting equipment and better traffic control strategies at work zones, specifically during adverse weather conditions.展开更多
In light of the possibility of reignition when unsealing the closed fire zones, the occurrence of reignition was simulated by a home-made experimental device, hydrogen variety rule from combustion to unsealing was ana...In light of the possibility of reignition when unsealing the closed fire zones, the occurrence of reignition was simulated by a home-made experimental device, hydrogen variety rule from combustion to unsealing was analyzed, the three-stage generation model of hydrogen during reignition in fire zone was put forward and the probability that hydrogen was taken as an indicator gas was discussed. The results show that: when fire zone is ready to unseal, which is filled with hydrogen at a high concentration, it is more prone to reignite.展开更多
Considering the promotion effect of interlaminar normal tensile stress and the inhibition effect of interlaminar normal compressive stress,two kinds of elimination initial criteria were proposed in this paper.Based on...Considering the promotion effect of interlaminar normal tensile stress and the inhibition effect of interlaminar normal compressive stress,two kinds of elimination initial criteria were proposed in this paper.Based on these two delamination initial criteria,a modified cohesive zone model(CZM)was established to simulate the delamination behavior in laminated composites.Numerical simulations of double cantilever beam(DCB),mixed-mode bending(MMB)and end notched flexure(ENF)tests were conducted.The results show that the proposed model can do a better job than common ones when it is used to predict laminates’delamination under interlaminar compression stress.Moreover,a factor r,named cohesive strength coefficient,was defined in this paper on account of the difference between cohesive strength and interlaminar fracture strength.With changing factor r,it shows that a moderate variation of cohesive strength will not cause significant influences on global load-displacement responses.Besides,in order to obtain a good balance between prediction accuracy and computational efficiency,there shall be two or three numerical elements within the cohesive zone.展开更多
Investigation of paper cutting process is vital for the design of cutting tools,but the fracture mechanism of paper cutting is still unclear.Here,we focus on the cutting process of paper,including the key parameters o...Investigation of paper cutting process is vital for the design of cutting tools,but the fracture mechanism of paper cutting is still unclear.Here,we focus on the cutting process of paper,including the key parameters of cohesive zone model(CZM)for the orthotropic paper,to simulate the shear fracture process.Firstly,the material constants of the orthotropic paper are determined by longitudinal and transverse tensile test.Secondly,based on the tensile stressstrain curves,combined with damage theory and numerical simulations,the key parameters of the CZM for the orthotropic paper are obtained.Finally,a model III fracture is simulated to verify the accuracy of the model.Results show that the load-displacement curves obtained by the simulation is consistent with the test results.展开更多
Objective: To analyze longitudinal binary data by using generalized linear models. The correlation between repeated measures were considered. The general method for analyzing longitudinal binary data was given. Method...Objective: To analyze longitudinal binary data by using generalized linear models. The correlation between repeated measures were considered. The general method for analyzing longitudinal binary data was given. Methods: Generalized estimating equations (GEE) proposed by Zeger and Liang was used. For sevens covariance structures, one method was given for estimating regression and correlation parameters. Results: Regression and coerelation parameters were estimated simultaneously. A Set of program was finished and an example was illustrated. Conclusion: Longitudinal dsta often occur in medical researches and clinical trials. For solving the problem of correlation between repeated measures, it is necessary to use some special methods to cope with this Kind of data.展开更多
The evolution of faults within the same stress field is frequently influenced by numerous factors,involving the reactivation of pre-existing structures,stress transmission through ductile detachment layers,and the gro...The evolution of faults within the same stress field is frequently influenced by numerous factors,involving the reactivation of pre-existing structures,stress transmission through ductile detachment layers,and the growth,interaction,as well as linkage of new fault segments.This study analyses a complex multi-phase oblique extension fault system in the Nanpu Sag(NPS)of the Bohai Bay Basin(BBB),China.High-resolution three-dimensional(3D)seismic data and analogue modelling indicate that the oblique extensional reactivation of pre-existing structures governs the sequential arrangement of fault segments in the caprock,and they dip synthetically to the reactivated fault at depth.During the NW-SE extension in the Eocene,the predominant movement of the pre-existing fault is strike-slip.Subsequently,during the N-S extension since the Oligocene,inclined at 20.to the pre-existing fault,forming splay fault segments and ultimately creating large en-echelon arcuate faults linked by relay ramps.Using fault throw-distance(T-D)and laser scanning,we reconstructed the fault evolution model of oblique extension reactivation in the presence of a ductile detachment basement.Our study illustrates that the arcuate faults can be categorized into linear master fault segments controlled by pre-existing structures,bending splay faults in the termination zone,and normal fault segments responding to the regional stress field.The interaction between faults occurs among normal faults and strike-slip faults,and the kinematic unification of the two fault systems is accomplished in the intersection zone.As the faults continue to evolve,the new fault segments tend to relinquish the control of pre-existing structures and concentrate more on the development of planar and continuous major faults.The ductile detachment layer significantly contributes to the uniform distribution of strain,resulting in narrow shear zones and discontinuous normal faults in its absence.展开更多
射频前端芯片的多功能一体化设计对晶体管模型的功能及其复用能力提出了更高的要求。然而,传统模型无法实现多功能复用,导致模型参数提取步骤多、建模效率低。对此,本文提出了一种基于准物理区划分(Quasi-physical zone division, QPZD...射频前端芯片的多功能一体化设计对晶体管模型的功能及其复用能力提出了更高的要求。然而,传统模型无法实现多功能复用,导致模型参数提取步骤多、建模效率低。对此,本文提出了一种基于准物理区划分(Quasi-physical zone division, QPZD)理论的多功能的器件物理基建模方法,模型具备非线性、噪声和开关特性的表征能力。首先,本文阐述了QPZD的建模原理,分别介绍了基于QPZD的非线性、微波噪声和开关三类单功能模型理论,并基于统一的核心模型方程提出了上述模型的一体化融合方法及其多功能模型架构。其次,介绍了包括自热效应、环境温度效应和陷阱效应在内的色散效应的建模方法。最后,从晶体管在片测试验证和射频前端多功能芯片设计验证两个角度对建立的模型进行了验证。仿真实测对比结果表明,模型的非线性、噪声和开关特性的综合仿真精度大于80.33%。本文的建模方法对多功能射频前端关键芯片的全面和精准设计具有重要的指导意义。展开更多
文摘A peptides migration model based on the principle of mechanics is presented in capillary zone electrophoresis (CZE). It is shown that the migration that the (tr) is a function of electric (Q), relative molecular mass (Mr), conformation parameter (Rc) of peptides and electrophoretic condition parameter(A). The conformation parameter is introduced to characterize multifarious shapes owing to the complex conlormation and the various kinds of macromolecules, where Rc≥1/3. The parameters A and Rc can be obtained from experimental data. The times of migration of the nine standard peptides were measured in pH 2.5buffer on different electrophoretic conditions in CZE. The experimental results agreed well with the theoretical prediction.
基金sponsored by the Federal Highway Administration(FHWA)in cooperation with the American Association of State Highway and Transportation Officials(AASHTO)
文摘Identifying risk factors for road traffic injuries can be considered one of the main priorities of transportation agencies. More than 12,000 fatal work zone crashes were reported between 2000 and 2013. Despite recent efforts to improve work zone safety, the frequency and severity of work zone crashes are still a big concern for transportation agencies. Although many studies have been conducted on different work zone safety-related issues, there is a lack of studies that investigate the effect of adverse weather conditions on work zone crash severity. This paper utilizes probit–classification tree, a relatively recent and promising combination of machine learning technique and conventional parametric model, to identify factors affecting work zone crash severity in adverse weather conditions using 8 years of work zone weatherrelated crashes (2006–2013) in Washington State. The key strength of this technique lies in its capability to alleviate the shortcomings of both parametric and nonparametric models. The results showed that both presence of traffic control device and lighting conditions are significant interacting variables in the developed complementary crash severity model for work zone weather-related crashes. Therefore, transportation agencies and contractors need to invest more in lighting equipment and better traffic control strategies at work zones, specifically during adverse weather conditions.
基金supported by the National Natural Science Foundation of China (No.50604014)the Program for New Century Excellent Talent Project(No.NCET-08-0838)the Research Fund of the State Key Laboratory of Coal Resources and Safe Mining,CUMT (No.09KF11)
文摘In light of the possibility of reignition when unsealing the closed fire zones, the occurrence of reignition was simulated by a home-made experimental device, hydrogen variety rule from combustion to unsealing was analyzed, the three-stage generation model of hydrogen during reignition in fire zone was put forward and the probability that hydrogen was taken as an indicator gas was discussed. The results show that: when fire zone is ready to unseal, which is filled with hydrogen at a high concentration, it is more prone to reignite.
文摘Considering the promotion effect of interlaminar normal tensile stress and the inhibition effect of interlaminar normal compressive stress,two kinds of elimination initial criteria were proposed in this paper.Based on these two delamination initial criteria,a modified cohesive zone model(CZM)was established to simulate the delamination behavior in laminated composites.Numerical simulations of double cantilever beam(DCB),mixed-mode bending(MMB)and end notched flexure(ENF)tests were conducted.The results show that the proposed model can do a better job than common ones when it is used to predict laminates’delamination under interlaminar compression stress.Moreover,a factor r,named cohesive strength coefficient,was defined in this paper on account of the difference between cohesive strength and interlaminar fracture strength.With changing factor r,it shows that a moderate variation of cohesive strength will not cause significant influences on global load-displacement responses.Besides,in order to obtain a good balance between prediction accuracy and computational efficiency,there shall be two or three numerical elements within the cohesive zone.
基金supported by the National Natural Science Foundation of China(No.11702147)。
文摘Investigation of paper cutting process is vital for the design of cutting tools,but the fracture mechanism of paper cutting is still unclear.Here,we focus on the cutting process of paper,including the key parameters of cohesive zone model(CZM)for the orthotropic paper,to simulate the shear fracture process.Firstly,the material constants of the orthotropic paper are determined by longitudinal and transverse tensile test.Secondly,based on the tensile stressstrain curves,combined with damage theory and numerical simulations,the key parameters of the CZM for the orthotropic paper are obtained.Finally,a model III fracture is simulated to verify the accuracy of the model.Results show that the load-displacement curves obtained by the simulation is consistent with the test results.
文摘Objective: To analyze longitudinal binary data by using generalized linear models. The correlation between repeated measures were considered. The general method for analyzing longitudinal binary data was given. Methods: Generalized estimating equations (GEE) proposed by Zeger and Liang was used. For sevens covariance structures, one method was given for estimating regression and correlation parameters. Results: Regression and coerelation parameters were estimated simultaneously. A Set of program was finished and an example was illustrated. Conclusion: Longitudinal dsta often occur in medical researches and clinical trials. For solving the problem of correlation between repeated measures, it is necessary to use some special methods to cope with this Kind of data.
基金funded by the National Natural Science Foundation of China (grant No.41472116)the Jidong Oil Company of China National Petroleum Corporation (grant No.JDYT-2017-JS-308)the Beijing Research Centre of China National Offshore Oil Company (grant No.CCL2022RCPS2017XNN)。
文摘The evolution of faults within the same stress field is frequently influenced by numerous factors,involving the reactivation of pre-existing structures,stress transmission through ductile detachment layers,and the growth,interaction,as well as linkage of new fault segments.This study analyses a complex multi-phase oblique extension fault system in the Nanpu Sag(NPS)of the Bohai Bay Basin(BBB),China.High-resolution three-dimensional(3D)seismic data and analogue modelling indicate that the oblique extensional reactivation of pre-existing structures governs the sequential arrangement of fault segments in the caprock,and they dip synthetically to the reactivated fault at depth.During the NW-SE extension in the Eocene,the predominant movement of the pre-existing fault is strike-slip.Subsequently,during the N-S extension since the Oligocene,inclined at 20.to the pre-existing fault,forming splay fault segments and ultimately creating large en-echelon arcuate faults linked by relay ramps.Using fault throw-distance(T-D)and laser scanning,we reconstructed the fault evolution model of oblique extension reactivation in the presence of a ductile detachment basement.Our study illustrates that the arcuate faults can be categorized into linear master fault segments controlled by pre-existing structures,bending splay faults in the termination zone,and normal fault segments responding to the regional stress field.The interaction between faults occurs among normal faults and strike-slip faults,and the kinematic unification of the two fault systems is accomplished in the intersection zone.As the faults continue to evolve,the new fault segments tend to relinquish the control of pre-existing structures and concentrate more on the development of planar and continuous major faults.The ductile detachment layer significantly contributes to the uniform distribution of strain,resulting in narrow shear zones and discontinuous normal faults in its absence.
文摘射频前端芯片的多功能一体化设计对晶体管模型的功能及其复用能力提出了更高的要求。然而,传统模型无法实现多功能复用,导致模型参数提取步骤多、建模效率低。对此,本文提出了一种基于准物理区划分(Quasi-physical zone division, QPZD)理论的多功能的器件物理基建模方法,模型具备非线性、噪声和开关特性的表征能力。首先,本文阐述了QPZD的建模原理,分别介绍了基于QPZD的非线性、微波噪声和开关三类单功能模型理论,并基于统一的核心模型方程提出了上述模型的一体化融合方法及其多功能模型架构。其次,介绍了包括自热效应、环境温度效应和陷阱效应在内的色散效应的建模方法。最后,从晶体管在片测试验证和射频前端多功能芯片设计验证两个角度对建立的模型进行了验证。仿真实测对比结果表明,模型的非线性、噪声和开关特性的综合仿真精度大于80.33%。本文的建模方法对多功能射频前端关键芯片的全面和精准设计具有重要的指导意义。
