Two chiral stationary phases(BCDs and YBCDs) were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the sillica gel via 3-glyci-{dyloxypropyltrimethoxysilane...Two chiral stationary phases(BCDs and YBCDs) were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the sillica gel via 3-glyci-{dyloxypropyltrimethoxysilane} as a coupling agent. Using acetonitrile-TEAA as mobile phase, good enantiomeric resolutions were obtained for DL-aminoacide on BCDs and YBCDs, including Leucine, Threonine and Valine. It is also observed that the higher separation factor of threonine was at pH {7.11} for both of the column, and the optimal column temperatures of Leucine appeared at 30 ℃ or {40 ℃}, respectively for YBCDs and BCDs.展开更多
文摘Two chiral stationary phases(BCDs and YBCDs) were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the sillica gel via 3-glyci-{dyloxypropyltrimethoxysilane} as a coupling agent. Using acetonitrile-TEAA as mobile phase, good enantiomeric resolutions were obtained for DL-aminoacide on BCDs and YBCDs, including Leucine, Threonine and Valine. It is also observed that the higher separation factor of threonine was at pH {7.11} for both of the column, and the optimal column temperatures of Leucine appeared at 30 ℃ or {40 ℃}, respectively for YBCDs and BCDs.
