Objective:To evaluate effects of diagnostic tests for Helicobacter pylori(H.pylori)infec- tion.Methods:A meta-analysis was conducted in 22 identified studies through Chinese literature searching which were published a...Objective:To evaluate effects of diagnostic tests for Helicobacter pylori(H.pylori)infec- tion.Methods:A meta-analysis was conducted in 22 identified studies through Chinese literature searching which were published after 1995 and evaluated diagnostic tests for Helicobacter pylori(H.pylori)infec- tion.Results:Polymerase chain reaction(PCR)had the best performance with diagnostic odds ratio (DOR)of 6.7(5.5-7.8),followed by ^(13)C urea breath test and Enzyme-linked immunosorbent assay (ELISA)quantitative serological test,with DOR being 6.4(5.4-7.4)and 4.5(3.8-5.2),respectively. Conclusion:Non-invasive tests are the appropriate methods for screening H.pylori infection,whereas in- vasive tests are the best methods for ascertaining the suspected patients.展开更多
文摘Objective:To evaluate effects of diagnostic tests for Helicobacter pylori(H.pylori)infec- tion.Methods:A meta-analysis was conducted in 22 identified studies through Chinese literature searching which were published after 1995 and evaluated diagnostic tests for Helicobacter pylori(H.pylori)infec- tion.Results:Polymerase chain reaction(PCR)had the best performance with diagnostic odds ratio (DOR)of 6.7(5.5-7.8),followed by ^(13)C urea breath test and Enzyme-linked immunosorbent assay (ELISA)quantitative serological test,with DOR being 6.4(5.4-7.4)and 4.5(3.8-5.2),respectively. Conclusion:Non-invasive tests are the appropriate methods for screening H.pylori infection,whereas in- vasive tests are the best methods for ascertaining the suspected patients.