Texture evolution and inhomogeneous deformation of polycrystalline Cu during uniaxial compression are investigated at the grain scale by combining crystal plasticity finite element method(CPFEM) with particle swarm op...Texture evolution and inhomogeneous deformation of polycrystalline Cu during uniaxial compression are investigated at the grain scale by combining crystal plasticity finite element method(CPFEM) with particle swarm optimization(PSO) algorithm. The texture-based representative volume element(TBRVE) is used in the crystal plasticity finite element model, where a given number of crystallographic orientations are obtained by means of discretizing the orientation distribution function(ODF) based on electron backscattered diffraction(EBSD) experiment data. Three-dimensional grains with different morphologies are generated on the basis of Voronoi tessellation. The PSO algorithm plays a significant role in identifying the material parameters and saving computational time. The macroscopic stress–strain curve is predicted based on CPFEM, where the simulation results are in good agreement with the experimental ones. Therefore, CPFEM is a powerful candidate for capturing the texture evolution and clarifying the inhomogeneous plastic deformation of polycrystalline Cu. The simulation results indicate that the <110> fiber texture is generated finally with the progression of plastic deformation. The inhomogeneous distribution of rotation angles lays the foundation for the inhomogeneous deformation of polycrystalline Cu in terms of grain scale.展开更多
The predictive capacity of numerical analyses in geotechnical engineering depends strongly on the efficiency of constitutive models used for modeling of interfaces behavior.Interfaces are considered as thin layers of ...The predictive capacity of numerical analyses in geotechnical engineering depends strongly on the efficiency of constitutive models used for modeling of interfaces behavior.Interfaces are considered as thin layers of the soil adjacent to structures boundary whose major role is transferring loads from structures to soil masses.An interface model within the bounding surface plasticity framework and the critical state soil mechanics is presented.To this aim,general formulation of the interface model according to the bounding surface plasticity theory is described first.Similar to granular soils,it has been shown that the mechanical behavior of sand-structure interfaces is highly affected by the interface state that is the combined influences of density and applied normal stress.Therefore,several ingredients of the model are directly related to the interface state.As a result of this feature,the model is enabled to distinguish interfaces in dense state from those in loose state and to provide realistic predictions over wide ranges of density and normal stress values.In evaluation of the model,a reasonable correspondence between the model predictions and the experimental data of various research teams is found.展开更多
The need to develop armour systems to protect against attacks from various sources is increasingly a matter of personal,social and national security.To develop innovative armour systems it is necessary to monitor deve...The need to develop armour systems to protect against attacks from various sources is increasingly a matter of personal,social and national security.To develop innovative armour systems it is necessary to monitor developments being made on the type,technology and performance of the threats(weapons,projectiles,explosives,etc.) Specifically,the use of high protection level helmets on the battlefield is essential.The development of evaluation methods that can predict injuries and trauma is therefore of major importance.However,the risk of injuries or trauma that can arise from induced accelerations is an additional consideration.To develop new materials and layouts for helmets it is necessary to study the effects caused by ballistic impacts in the human head on various scenarios.The use of numerical simulation is a fundamental tool in this process.The work here presented focuses on the use of numerical simulation(finite elements analysis) to predict the consequences of bullet impacts on military helmets on human injuries.The main objectives are to assess the level and probability of head trauma using the Head Injury Criterion,caused by the impact of a 9 mm NATO projectile on a PASGT helmet and to quantify the relevance of projectile plasticity on the whole modelling process.The accelerations derived from the impact phenomenon and the deformations caused on the helmet are evaluated using fully three-dimensional models of the helmet,head,neck and projectile.Impact studies are done at impact angles ranging from 0 to 75°.Results are presented and discussed in terms of HIC and probability of acceleration induced trauma levels.Thorough comparison analyses are done using a rigid and a deformable projectile and it is observed that plastic deformation of the projectile is a significant energy dissipation mechanism in the whole impact process.展开更多
Based on the pseudo potential plane-wave method of density functional theory （DFT）, Ti1-xNbxAk （x=0, 0.062 5, 0.083 3, 0.125, 0.250） crystals＇ geometry structure, elastic constants, electronic structure and Mulli...Based on the pseudo potential plane-wave method of density functional theory （DFT）, Ti1-xNbxAk （x=0, 0.062 5, 0.083 3, 0.125, 0.250） crystals＇ geometry structure, elastic constants, electronic structure and Mulliken populations were calculated, and the effects of doping on the geometric structure, electronic structure and bond strength were systematically analyzed. The results show that the influence of Nb on the geometric structure is little in terms of the plasticity, and with the increase of Nb content, the covalent bond strength remarkably reduces, and Ti-Al, Nb-M （M=Ti, Al） and other hybrid bonds enhance; meanwhile, the peak district increases and the pseudo-energy gap first decreases and then increases, the overall band structure narrows, the covalent bond and direction of bonds reduce. The population analysis also shows that the results are consistent with the electronic structure analysis. The density of states of TiAINb shows that Nb doping can enhance the activity of Al and benefit the form of Al2O3 film. All the calculations reveal that the room temperature plasticity and the antioxidation properties of the compounds can be improved with the Nb content of 8.33%-12.5% （mole fraction）.展开更多
The distribution of shear stress on the cross-section of plastic metal solid circular shaft under pure torsion yielding, the applicability of complete plastic model assumption and the shear stress formula were researc...The distribution of shear stress on the cross-section of plastic metal solid circular shaft under pure torsion yielding, the applicability of complete plastic model assumption and the shear stress formula were researched. Based on the shear stress formula of circular shaft under pure torsion in elastic stage, the formula of torque in elastic stage and the definition of yield, it is obtained that the yielding stage of plastic metal shaft under pure torsion is only a surface phenomenon of torque-torsion angle relationship, and the distribution of shear stress is essentially different from that of tensile stress when yielding under uniaxial tension. The pure torsion platform-torsion angle and the shape of torque-torsion angle curve cannot change the distribution of shear stress on the shaft cross-section. The distribution of shear stress is still linear with the maximum shear stress ts. The complete plasticity model assumption is not in accordance with the actual situation of shaft under torsion. The experimental strength data of nine plastic metals are consistent with the calculated results of the new limiting strain energy strength theory （LSEST）. The traditional yield stress formula for plastic shaft under torsion is reasonable. The shear stress formula based on the plane assumption in material mechanics is applicable for all loaded stages of torsion shaft.展开更多
OBJECTIVE Currently, almost all chemical compounds or biological reagents to reverse or slow down the AD process have failed in clinical trials. An integrative and multi-targeted strategy is increasingly appreciated t...OBJECTIVE Currently, almost all chemical compounds or biological reagents to reverse or slow down the AD process have failed in clinical trials. An integrative and multi-targeted strategy is increasingly appreciated to effectively combat this devastating disease. Traditional Chinese medicine(TCM) has been widely used for treatment of dementia, and thus the advantages of the potential therapeutic features of TCM treatment and associated mechanisms should be well taken. The Amnesia Remedy Formula(ARF) was invented by one of the most influential Master of TCM SUN Si-miao, who lived for about 100 year old. The aim of this research is to characterize the time course changes of the cognitive behaviors post a ARF, and the mechanism underlying the effects, focusing on PKA-centered signaling for both enhancement of neural plasticity and clearance of the phosphorylated Tau. RESULTS We tested the efficacy of ARF on two animal models of AD, and examine the central role of PKA signaling in the enhancement of neural plasticity via PKA/CREB/BDNF pathway as well as clearance of toxic p Tau via PKA/GSK3β/p Tau pathway. In the scopolamine model, ARF effectively reversed the memory in Morris water maze(MWM) test, with some features superior to anti-AD drug donepezil. In a battery test of MWM, novel object recognition or T maze in 5-month-old senescenceaccelerated mouse prone 8(SAMP8) strain mice, two weeks of administration of ARF showed overall better improvement in memory loss than donepezil, and the effect lasted for at least 1 week after termination of administration of the formula. ARF increased expression of PKA/CREB/BDNF and synaptic proteins PSD95 expression, as well as enhanced Ser9 phosphorylation of GSK3β, thus reduced p Tau in the hippocampus. Blockade of PKA signaling blunted the anti-AD-like effect of ARF, with reversal of CREB/BDNF signaling. Transcriptomic analysis indicated some changes of novel molecules along this pathway may be part of the pathological and therapeutic mechanism, which warrants further investigation. CONCLUSION ARF may display some advantageous features in treating AD with early onset, via multi-targeted manner including enhancement of neural plasticity and reduction in Tau toxicity.展开更多
The relationship between the crystal lattice free volume,ΔV,and impact sensitivity,E_(dr),of ten nitramines has been analyzed. It was found that this relationship is not uniquely determined,i. e. it is not given only...The relationship between the crystal lattice free volume,ΔV,and impact sensitivity,E_(dr),of ten nitramines has been analyzed. It was found that this relationship is not uniquely determined,i. e. it is not given only by their own ΔV values but fundamentally by the type and intensity of the intermolecular forces in the nitramine crystals. Also,relationships between the E_(dr)values,on the one hand,and bulk modulus,K,and shear modulus,G,on the other,have been the subject of discussion not only for pure cyclic nitramines but also for their PBXs,bonded by a poly-fluoro binder. The closest linear correlation exists between the E_(dr)values and dimensionless K·G^(-1) ratio which indicates the plasticity range. A similar relationship is valid also for the ΔV values. Relationships of the E_(dr) and / or ΔV values with the shear modulus or to the K·G^(-1) ratio reflect an unusual behavior of ε-HNIW to which the published morphological instability of this particular HNIW version might also be related.展开更多
This work identified the important role of matrix mechanical plasticity in mediating fibroblast activation.Many existing studies have highlighted the important effects of biochemical cues(e.g.,transforming growth fact...This work identified the important role of matrix mechanical plasticity in mediating fibroblast activation.Many existing studies have highlighted the important effects of biochemical cues(e.g.,transforming growth factor-β1)and mechanicalstiffness on fibroblast activation.Our results indicated that self-assembled collagen hydrogels showed high plasticity and in which fibroblasts remain undifferentiated.However,when we decreased the plasticity of collagen hydrogels by increasing covalent crosslinking,fibroblasts showed a significant fibrotic response as reflected by the increasedα-SMA expression.Since the material systems we constructed have low and the same initial modulus,this process is stiffness independent.Although it has been reported that covalently crosslinked hydrogels are more difficult to degrade and matrix degradability has an important impact on cell behaviors,no significant changes of fibroblast activation were observed when proteases were broadly inhibited in our experiments.Importantly,the hydrogels we constructed showed similar plastic behaviors under creep and recovery tests compared to native normal and fibrotic tissues.These highlight the importance of matrix plasticity in mimicking the mechanical microenvironment of native fibrotic tissues.Mechanistically,we found that the enhanced fibroblast activation in low plastic matrix is mediated through integrin-actin pathway and nuclear localization of YAP.In high plastic collagen,matrix cannot provide effective resistance to actin contraction because of the rupture of weak crosslinks and the slippage of local fibers.On the contrary,in low plastic collagen,deformation energy can be stored in the network due to the existence of strong covalent crosslinks,thus enabling the build-up of cell traction and the formation of a robust cell-matrix interaction.Experiments of inhibiting or promoting cytoskeletal contractility and CGMD simulation both verified the above points.Our results clarify plasticity changes on the development of fibrotic diseases and highlight plasticity as an important mechanical cue in understanding cell-matrix interactions.展开更多
OBJECTIVE To investigate whether electroacupuncture(EA)ameliorates abnormal trigeminal neuralgia(TN)orofacial pain and anxiety-like behavior by altering synaptic plasticity in the hippocampus CA1.METHODS A mouse infra...OBJECTIVE To investigate whether electroacupuncture(EA)ameliorates abnormal trigeminal neuralgia(TN)orofacial pain and anxiety-like behavior by altering synaptic plasticity in the hippocampus CA1.METHODS A mouse infraorbital nerve transection model(pTION)of neuropathic pain was established,and EA or sham EA was used to treat ipsilateral acu⁃puncture points(GV20-Baihui and ST7-Xia⁃guan).Golgi-Cox staining and transmission elec⁃tron microscopy(TEM)were administrated to observe the changes of synaptic plasticity in the hippocampus CA1.RESULTS Stable and persistent orofacial allodynia and anxiety-like behav⁃iors induced by pT-ION were related to changes in hippocampal synaptic plasticity.Golgi stain⁃ings showed a decrease in the density of dendritic spines,especially mushroom-type dendritic spines,in hippocampal CA1 neurons of pT-ION mice.TEM results showed that the density of synapses,membrane thickness of the postsynaptic density,and length of the synaptic active zone were decreased,whereas the width of the synaptic cleft was increased in pTION mice.EA attenu⁃ated pT-ION-induced orofacial allodynia and anx⁃iety-like behaviors and effectively reversed the abnormal changes in dendritic spines and syn⁃apse of the hippocampal CA1 region.CONCLU⁃SION EA modulates synaptic plasticity of hippo⁃campal CA1 neurons,and reduces abnormal oro⁃facial pain and anxiety-like behavior,providing evidence for a TN treatment strategy.展开更多
Compaction processes are one the most important par ts of powder forming technology. The main applications are focused on pieces for a utomotive, aeronautic, electric and electronic industries. The main goals of the c...Compaction processes are one the most important par ts of powder forming technology. The main applications are focused on pieces for a utomotive, aeronautic, electric and electronic industries. The main goals of the compaction processes are to obtain a compact with the geometrical requirements, without cracks, and with a uniform distribution of density. Design of such proc esses consist, essentially, in determine the sequence and relative displacements of die and punches in order to achieve such goals. A.B. Khoei presented a gener al framework for the finite element simulation of powder forming processes based on the following aspects; a large displacement formulation, centred on a total and updated Lagrangian formulation; an adaptive finite element strategy based on error estimates and automatic remeshing techniques; a cap model based on a hard ening rule in modelling of the highly non-linear behaviour of material; and the use of an efficient contact algorithm in the context of an interface element fo rmulation. In these references, the non-linear behaviour of powder was adequately desc ribed by the cap plasticity model. However, it suffers from a serious deficiency when the stress-point reaches a yield surface. In the flow theory of plasticit y, the transition from an elastic state to an elasto-plastic state appears more or less abruptly. For powder material it is very difficult to define the locati on of yield surface, because there is no distinct transition from elastic to ela stic-plastic behaviour. Results of experimental test on some hard met al powder show that the plastic effects were begun immediately upon loading. In such mater ials the domain of the yield surface would collapse to a point, so making the di rection of plastic increment indeterminate, because all directions are normal to a point. Thus, the classical plasticity theory cannot deal with such materials and an advanced constitutive theory is necessary. In the present paper, the constitutive equations of powder materials will be discussed via an endochronic theory of plasticity. This theory provides a unifi ed point of view to describe the elastic-plastic behaviour of material since it places no requirement for a yield surface and a ’loading function’ to disting uish between loading an unloading. Endochronic theory of plasticity has been app lied to a number of metallic materials, concrete and sand, but to the knowledge of authors, no numerical scheme of the model has been applied to powder material . In the present paper, a new approach is developed based on an endochronic rate independent, density-dependent plasticity model for describing the isothermal deformation behavior of metal powder at low homologous temperature. Although the concept of yield surface has not been explicitly assumed in endochronic theory, it is shown that the cone-cap plasticity yield surface (Fig.1), which is the m ost commonly used plasticity models for describing the behavior of powder materi al can be easily derived as a special case of the proposed endochronic theory. Fig.1 Trace of cone-cap yield function on the meridian pl ane for different relative density As large deformation is observed in powder compaction process, a hypoelastic-pl astic formulation is developed in the context of finite deformation plasticity. Constitutive equations are stated in unrotated frame of reference that greatly s implifies endochronic constitutive relation in finite plasticity. Constitutive e quations of the endochronic theory and their numerical integration are establish ed and procedures for determining material parameters of the model are demonstra ted. Finally, the numerical schemes are examined for efficiency in the model ling of a tip shaped component, as shown in Fig.2. Fig.2 A shaped tip component. a) Geometry, boundary conditio n and finite element mesh; b) density distribution at final stage of展开更多
A new dimensionless number is proposed for dynamic plastic deformation analysis of clamped circular plates under underwater explosion loads by introducing dimensional analysis method to the basic dynamical governing e...A new dimensionless number is proposed for dynamic plastic deformation analysis of clamped circular plates under underwater explosion loads by introducing dimensional analysis method to the basic dynamical governing equations of circular plates.The relation between dimensionless final plastic deformation of circular plates and the new dimensionless number is established based on massive underwater explosion test data.Meanwhile,comparative analysis was discussed with two other published dimensionless parameters which indicated the new dimensionless number proposed in this paper is more effective and extensive to predict the dynamic plastic response of circular plates under underwater explosion condition.展开更多
This work describes thermal decomposition behaviour of plastic bonded explosives(PBXs) based on mixture of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane(HMX) and 2,4,6-triamino-1,3,5-trinitrobenzene(TATB)with Viton A as poly...This work describes thermal decomposition behaviour of plastic bonded explosives(PBXs) based on mixture of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane(HMX) and 2,4,6-triamino-1,3,5-trinitrobenzene(TATB)with Viton A as polymer binder. Thermal decomposition of PBXs was undertaken by applying simultaneous thermal analysis(STA) and differential scanning calorimetry(DSC) to investigate influence of the HMX amount on thermal behavior and its kinetics. Thermogravimetric analysis(TGA) indicated that the thermal decomposition of PBXs based on mixture of HMX and TATB was occurred in a three-steps. The first step was mainly due to decomposition of HMX. The second step was ascribed due to decomposition of TATB, while the third step was occurred due to decomposition of the polymer matrices. The thermal decomposition % was increased with increasing HMX amount. The kinetics related to thermal decomposition were investigated under non-isothermal for a single heating rate measurement. The variation in the activation energy of PBXs based on mixture of HMX and TATB was observed with varying the HMX amount. The kinetics from the results of TGA data at various heating rates under non-isothermal conditions were also calculated by Flynn—Wall—Ozawa(FWO) and Kissinger-Akahira-Sunose(KAS)methods. The activation energies calculated by employing FWO method were very close to those obtained by KAS method. The mean activation energy calculated by FWO and KAS methods was also a good agreement with the activation energy obtained from single heating rate measurement in the first step decomposition.展开更多
Cross-wedge rolling (CWR) is a metal process of ro ta ry forming. To produce a part, one cylindrical billet should be placed between t wo counterrotating and wedge-shape dies, which move tangentially relative each oth...Cross-wedge rolling (CWR) is a metal process of ro ta ry forming. To produce a part, one cylindrical billet should be placed between t wo counterrotating and wedge-shape dies, which move tangentially relative each other. The billet suffers plastic deformation (essentially, localized compressio n) during its rotation between the rotating dies. Compared to other numerical si mulation methods, the finite element method (FEM) has advantages in solving gene ral problems with complex shapes of the formed parts. In cross-wedge rolling, t here are four stages in the workpiece deformation process, namely knifing, guidi ng, stretching and sizing stage. It is time-consuming and expensive to design t he CWR process by trial and error method. The application of numerical simul ation for the CWR process will help engineers to efficiently improve the process development. Tselikov, Hayama, Jain and Kobayashi, and Higashimo applied the sl ip-line theory in study of CWR process analysis. Zb.pater studied CWR process i ncluding upsetting by upper-bound method. The above numerical simulation were b ased on the two-dimensional plain-strain assumption ignored the metal flow in workpiece axial direction. Therefore, the complex three-dimensional stress and deformation involved in CWR processes were not presented. Compared to other nume rical simulation methods, the finite element method (FEM) has advantages in solv ing general problems with complex shapes of the formed parts. As yet, a few 3-D finite element simulation studies on CWR process have been reported in literatu res. In this paper, the process of cross wedge rolling (CWR) has been simulated and analyzed by 3D rigid-plastic finite element method. Considering the charact eristic of CWR, the static implicit FEM program is selected. The models proposed in this study uses the commercial code DEFORM 3D to simulate the CWR process. T his is an implicit Lagrangian finite element code, which includes many new enhan cements functions. A new method of utilizing multiple processors using the MPI s tandard has been implemented. Automatic switching between the two different defo rmation solvers (Sparse Solver and Conjugate Gradient Solver) has also been impl emented in order to increase the speed of simulations. In this paper, all stages in CWR process are simulated to be able to closely understand and analyze the a ctual CWR process. For simulating all forming stages in CWR process, the dynam ic adaptive remeshing technology for tetrahedral solid elements was applied. T he stress distributions in cross section of forming workpiece are analyzed to in terpret fracture or rarefaction in the center of workpiece. Authors also analyze d the time-torque curve and the laws of load changing.展开更多
In order to improve the properties of rice straw fiber film, one factor contrast test method was employed. Plasticizer type was chosen as input variable, dry tension strength and elongation, wet tension strength and e...In order to improve the properties of rice straw fiber film, one factor contrast test method was employed. Plasticizer type was chosen as input variable, dry tension strength and elongation, wet tension strength and elongation, bursting strength and tearing strength were chosen as indexes. The results showed that there were significant differences among the means of dry tension strength, dry elongation and bursting strength of different plasticizers; there were not significant differences among the means of wet tension strength, wet elongation and tearing strength of different plasticizers; for dry tension strength and elongation, glycerol had a significant difference with sorbitol and PEG, no significant difference was observed between sorbitol and PEG, dry tension strength added glycerol had been reduced 6.8% compared with that added sorbitol, reduced 9.5% compared with that added PEG; elongation had been improved 6.1% and 9.4%, respectively; for bursting strength, sorbitol had a significant difference with glycerol and PEG, no significant difference was observed between glycerol and PEG; bursting strength added glycerol and added PEG had been improved 6.9% and 5.6%, respectively compared with that of the added sorbitol. The results provided a theoretical reference for further improving the straw fiber film manufacturing process.展开更多
The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures hav...The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.展开更多
基金Projects(51305091,51475101) supported by the National Natural Science Foundation of ChinaProject(20132304120025) supported by Specialized Research Fund for the Doctoral Program of Higher Education,China
文摘Texture evolution and inhomogeneous deformation of polycrystalline Cu during uniaxial compression are investigated at the grain scale by combining crystal plasticity finite element method(CPFEM) with particle swarm optimization(PSO) algorithm. The texture-based representative volume element(TBRVE) is used in the crystal plasticity finite element model, where a given number of crystallographic orientations are obtained by means of discretizing the orientation distribution function(ODF) based on electron backscattered diffraction(EBSD) experiment data. Three-dimensional grains with different morphologies are generated on the basis of Voronoi tessellation. The PSO algorithm plays a significant role in identifying the material parameters and saving computational time. The macroscopic stress–strain curve is predicted based on CPFEM, where the simulation results are in good agreement with the experimental ones. Therefore, CPFEM is a powerful candidate for capturing the texture evolution and clarifying the inhomogeneous plastic deformation of polycrystalline Cu. The simulation results indicate that the <110> fiber texture is generated finally with the progression of plastic deformation. The inhomogeneous distribution of rotation angles lays the foundation for the inhomogeneous deformation of polycrystalline Cu in terms of grain scale.
文摘The predictive capacity of numerical analyses in geotechnical engineering depends strongly on the efficiency of constitutive models used for modeling of interfaces behavior.Interfaces are considered as thin layers of the soil adjacent to structures boundary whose major role is transferring loads from structures to soil masses.An interface model within the bounding surface plasticity framework and the critical state soil mechanics is presented.To this aim,general formulation of the interface model according to the bounding surface plasticity theory is described first.Similar to granular soils,it has been shown that the mechanical behavior of sand-structure interfaces is highly affected by the interface state that is the combined influences of density and applied normal stress.Therefore,several ingredients of the model are directly related to the interface state.As a result of this feature,the model is enabled to distinguish interfaces in dense state from those in loose state and to provide realistic predictions over wide ranges of density and normal stress values.In evaluation of the model,a reasonable correspondence between the model predictions and the experimental data of various research teams is found.
文摘The need to develop armour systems to protect against attacks from various sources is increasingly a matter of personal,social and national security.To develop innovative armour systems it is necessary to monitor developments being made on the type,technology and performance of the threats(weapons,projectiles,explosives,etc.) Specifically,the use of high protection level helmets on the battlefield is essential.The development of evaluation methods that can predict injuries and trauma is therefore of major importance.However,the risk of injuries or trauma that can arise from induced accelerations is an additional consideration.To develop new materials and layouts for helmets it is necessary to study the effects caused by ballistic impacts in the human head on various scenarios.The use of numerical simulation is a fundamental tool in this process.The work here presented focuses on the use of numerical simulation(finite elements analysis) to predict the consequences of bullet impacts on military helmets on human injuries.The main objectives are to assess the level and probability of head trauma using the Head Injury Criterion,caused by the impact of a 9 mm NATO projectile on a PASGT helmet and to quantify the relevance of projectile plasticity on the whole modelling process.The accelerations derived from the impact phenomenon and the deformations caused on the helmet are evaluated using fully three-dimensional models of the helmet,head,neck and projectile.Impact studies are done at impact angles ranging from 0 to 75°.Results are presented and discussed in terms of HIC and probability of acceleration induced trauma levels.Thorough comparison analyses are done using a rigid and a deformable projectile and it is observed that plastic deformation of the projectile is a significant energy dissipation mechanism in the whole impact process.
基金Project(07JJ3102) supported by Hunan Provincial Natural Science Foundation,ChinaProject(k0902132-11) supported by Changsha Municipal Science and Technology,China
文摘Based on the pseudo potential plane-wave method of density functional theory （DFT）, Ti1-xNbxAk （x=0, 0.062 5, 0.083 3, 0.125, 0.250） crystals＇ geometry structure, elastic constants, electronic structure and Mulliken populations were calculated, and the effects of doping on the geometric structure, electronic structure and bond strength were systematically analyzed. The results show that the influence of Nb on the geometric structure is little in terms of the plasticity, and with the increase of Nb content, the covalent bond strength remarkably reduces, and Ti-Al, Nb-M （M=Ti, Al） and other hybrid bonds enhance; meanwhile, the peak district increases and the pseudo-energy gap first decreases and then increases, the overall band structure narrows, the covalent bond and direction of bonds reduce. The population analysis also shows that the results are consistent with the electronic structure analysis. The density of states of TiAINb shows that Nb doping can enhance the activity of Al and benefit the form of Al2O3 film. All the calculations reveal that the room temperature plasticity and the antioxidation properties of the compounds can be improved with the Nb content of 8.33%-12.5% （mole fraction）.
文摘The distribution of shear stress on the cross-section of plastic metal solid circular shaft under pure torsion yielding, the applicability of complete plastic model assumption and the shear stress formula were researched. Based on the shear stress formula of circular shaft under pure torsion in elastic stage, the formula of torque in elastic stage and the definition of yield, it is obtained that the yielding stage of plastic metal shaft under pure torsion is only a surface phenomenon of torque-torsion angle relationship, and the distribution of shear stress is essentially different from that of tensile stress when yielding under uniaxial tension. The pure torsion platform-torsion angle and the shape of torque-torsion angle curve cannot change the distribution of shear stress on the shaft cross-section. The distribution of shear stress is still linear with the maximum shear stress ts. The complete plasticity model assumption is not in accordance with the actual situation of shaft under torsion. The experimental strength data of nine plastic metals are consistent with the calculated results of the new limiting strain energy strength theory （LSEST）. The traditional yield stress formula for plastic shaft under torsion is reasonable. The shear stress formula based on the plane assumption in material mechanics is applicable for all loaded stages of torsion shaft.
文摘OBJECTIVE Currently, almost all chemical compounds or biological reagents to reverse or slow down the AD process have failed in clinical trials. An integrative and multi-targeted strategy is increasingly appreciated to effectively combat this devastating disease. Traditional Chinese medicine(TCM) has been widely used for treatment of dementia, and thus the advantages of the potential therapeutic features of TCM treatment and associated mechanisms should be well taken. The Amnesia Remedy Formula(ARF) was invented by one of the most influential Master of TCM SUN Si-miao, who lived for about 100 year old. The aim of this research is to characterize the time course changes of the cognitive behaviors post a ARF, and the mechanism underlying the effects, focusing on PKA-centered signaling for both enhancement of neural plasticity and clearance of the phosphorylated Tau. RESULTS We tested the efficacy of ARF on two animal models of AD, and examine the central role of PKA signaling in the enhancement of neural plasticity via PKA/CREB/BDNF pathway as well as clearance of toxic p Tau via PKA/GSK3β/p Tau pathway. In the scopolamine model, ARF effectively reversed the memory in Morris water maze(MWM) test, with some features superior to anti-AD drug donepezil. In a battery test of MWM, novel object recognition or T maze in 5-month-old senescenceaccelerated mouse prone 8(SAMP8) strain mice, two weeks of administration of ARF showed overall better improvement in memory loss than donepezil, and the effect lasted for at least 1 week after termination of administration of the formula. ARF increased expression of PKA/CREB/BDNF and synaptic proteins PSD95 expression, as well as enhanced Ser9 phosphorylation of GSK3β, thus reduced p Tau in the hippocampus. Blockade of PKA signaling blunted the anti-AD-like effect of ARF, with reversal of CREB/BDNF signaling. Transcriptomic analysis indicated some changes of novel molecules along this pathway may be part of the pathological and therapeutic mechanism, which warrants further investigation. CONCLUSION ARF may display some advantageous features in treating AD with early onset, via multi-targeted manner including enhancement of neural plasticity and reduction in Tau toxicity.
文摘The relationship between the crystal lattice free volume,ΔV,and impact sensitivity,E_(dr),of ten nitramines has been analyzed. It was found that this relationship is not uniquely determined,i. e. it is not given only by their own ΔV values but fundamentally by the type and intensity of the intermolecular forces in the nitramine crystals. Also,relationships between the E_(dr)values,on the one hand,and bulk modulus,K,and shear modulus,G,on the other,have been the subject of discussion not only for pure cyclic nitramines but also for their PBXs,bonded by a poly-fluoro binder. The closest linear correlation exists between the E_(dr)values and dimensionless K·G^(-1) ratio which indicates the plasticity range. A similar relationship is valid also for the ΔV values. Relationships of the E_(dr) and / or ΔV values with the shear modulus or to the K·G^(-1) ratio reflect an unusual behavior of ε-HNIW to which the published morphological instability of this particular HNIW version might also be related.
基金financially supported by the National Natural Science Foundation of China ( 11872298, 11602191,11532009,11621062)the China Postdoctoral Science Foundation ( 2018M631141)the Fundamental Research Funds for the Central Universities ( Z201811336)
文摘This work identified the important role of matrix mechanical plasticity in mediating fibroblast activation.Many existing studies have highlighted the important effects of biochemical cues(e.g.,transforming growth factor-β1)and mechanicalstiffness on fibroblast activation.Our results indicated that self-assembled collagen hydrogels showed high plasticity and in which fibroblasts remain undifferentiated.However,when we decreased the plasticity of collagen hydrogels by increasing covalent crosslinking,fibroblasts showed a significant fibrotic response as reflected by the increasedα-SMA expression.Since the material systems we constructed have low and the same initial modulus,this process is stiffness independent.Although it has been reported that covalently crosslinked hydrogels are more difficult to degrade and matrix degradability has an important impact on cell behaviors,no significant changes of fibroblast activation were observed when proteases were broadly inhibited in our experiments.Importantly,the hydrogels we constructed showed similar plastic behaviors under creep and recovery tests compared to native normal and fibrotic tissues.These highlight the importance of matrix plasticity in mimicking the mechanical microenvironment of native fibrotic tissues.Mechanistically,we found that the enhanced fibroblast activation in low plastic matrix is mediated through integrin-actin pathway and nuclear localization of YAP.In high plastic collagen,matrix cannot provide effective resistance to actin contraction because of the rupture of weak crosslinks and the slippage of local fibers.On the contrary,in low plastic collagen,deformation energy can be stored in the network due to the existence of strong covalent crosslinks,thus enabling the build-up of cell traction and the formation of a robust cell-matrix interaction.Experiments of inhibiting or promoting cytoskeletal contractility and CGMD simulation both verified the above points.Our results clarify plasticity changes on the development of fibrotic diseases and highlight plasticity as an important mechanical cue in understanding cell-matrix interactions.
基金the National Natural Science Foundation of China(82001190)Natural Sci⁃ence Foundation of Shandong Province(ZR2021LZY016)+1 种基金Natural Science Foundation of Shandong Province(ZR2020MH348)Science and Technology Foundation of Shandong Traditional Chinese Medicine(2020Q035)。
文摘OBJECTIVE To investigate whether electroacupuncture(EA)ameliorates abnormal trigeminal neuralgia(TN)orofacial pain and anxiety-like behavior by altering synaptic plasticity in the hippocampus CA1.METHODS A mouse infraorbital nerve transection model(pTION)of neuropathic pain was established,and EA or sham EA was used to treat ipsilateral acu⁃puncture points(GV20-Baihui and ST7-Xia⁃guan).Golgi-Cox staining and transmission elec⁃tron microscopy(TEM)were administrated to observe the changes of synaptic plasticity in the hippocampus CA1.RESULTS Stable and persistent orofacial allodynia and anxiety-like behav⁃iors induced by pT-ION were related to changes in hippocampal synaptic plasticity.Golgi stain⁃ings showed a decrease in the density of dendritic spines,especially mushroom-type dendritic spines,in hippocampal CA1 neurons of pT-ION mice.TEM results showed that the density of synapses,membrane thickness of the postsynaptic density,and length of the synaptic active zone were decreased,whereas the width of the synaptic cleft was increased in pTION mice.EA attenu⁃ated pT-ION-induced orofacial allodynia and anx⁃iety-like behaviors and effectively reversed the abnormal changes in dendritic spines and syn⁃apse of the hippocampal CA1 region.CONCLU⁃SION EA modulates synaptic plasticity of hippo⁃campal CA1 neurons,and reduces abnormal oro⁃facial pain and anxiety-like behavior,providing evidence for a TN treatment strategy.
文摘Compaction processes are one the most important par ts of powder forming technology. The main applications are focused on pieces for a utomotive, aeronautic, electric and electronic industries. The main goals of the compaction processes are to obtain a compact with the geometrical requirements, without cracks, and with a uniform distribution of density. Design of such proc esses consist, essentially, in determine the sequence and relative displacements of die and punches in order to achieve such goals. A.B. Khoei presented a gener al framework for the finite element simulation of powder forming processes based on the following aspects; a large displacement formulation, centred on a total and updated Lagrangian formulation; an adaptive finite element strategy based on error estimates and automatic remeshing techniques; a cap model based on a hard ening rule in modelling of the highly non-linear behaviour of material; and the use of an efficient contact algorithm in the context of an interface element fo rmulation. In these references, the non-linear behaviour of powder was adequately desc ribed by the cap plasticity model. However, it suffers from a serious deficiency when the stress-point reaches a yield surface. In the flow theory of plasticit y, the transition from an elastic state to an elasto-plastic state appears more or less abruptly. For powder material it is very difficult to define the locati on of yield surface, because there is no distinct transition from elastic to ela stic-plastic behaviour. Results of experimental test on some hard met al powder show that the plastic effects were begun immediately upon loading. In such mater ials the domain of the yield surface would collapse to a point, so making the di rection of plastic increment indeterminate, because all directions are normal to a point. Thus, the classical plasticity theory cannot deal with such materials and an advanced constitutive theory is necessary. In the present paper, the constitutive equations of powder materials will be discussed via an endochronic theory of plasticity. This theory provides a unifi ed point of view to describe the elastic-plastic behaviour of material since it places no requirement for a yield surface and a ’loading function’ to disting uish between loading an unloading. Endochronic theory of plasticity has been app lied to a number of metallic materials, concrete and sand, but to the knowledge of authors, no numerical scheme of the model has been applied to powder material . In the present paper, a new approach is developed based on an endochronic rate independent, density-dependent plasticity model for describing the isothermal deformation behavior of metal powder at low homologous temperature. Although the concept of yield surface has not been explicitly assumed in endochronic theory, it is shown that the cone-cap plasticity yield surface (Fig.1), which is the m ost commonly used plasticity models for describing the behavior of powder materi al can be easily derived as a special case of the proposed endochronic theory. Fig.1 Trace of cone-cap yield function on the meridian pl ane for different relative density As large deformation is observed in powder compaction process, a hypoelastic-pl astic formulation is developed in the context of finite deformation plasticity. Constitutive equations are stated in unrotated frame of reference that greatly s implifies endochronic constitutive relation in finite plasticity. Constitutive e quations of the endochronic theory and their numerical integration are establish ed and procedures for determining material parameters of the model are demonstra ted. Finally, the numerical schemes are examined for efficiency in the model ling of a tip shaped component, as shown in Fig.2. Fig.2 A shaped tip component. a) Geometry, boundary conditio n and finite element mesh; b) density distribution at final stage of
基金supported by the National Natural Science Foundation of China(12402444)。
文摘A new dimensionless number is proposed for dynamic plastic deformation analysis of clamped circular plates under underwater explosion loads by introducing dimensional analysis method to the basic dynamical governing equations of circular plates.The relation between dimensionless final plastic deformation of circular plates and the new dimensionless number is established based on massive underwater explosion test data.Meanwhile,comparative analysis was discussed with two other published dimensionless parameters which indicated the new dimensionless number proposed in this paper is more effective and extensive to predict the dynamic plastic response of circular plates under underwater explosion condition.
基金DRDO(TBR-1251)for funding and awarding the Project
文摘This work describes thermal decomposition behaviour of plastic bonded explosives(PBXs) based on mixture of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane(HMX) and 2,4,6-triamino-1,3,5-trinitrobenzene(TATB)with Viton A as polymer binder. Thermal decomposition of PBXs was undertaken by applying simultaneous thermal analysis(STA) and differential scanning calorimetry(DSC) to investigate influence of the HMX amount on thermal behavior and its kinetics. Thermogravimetric analysis(TGA) indicated that the thermal decomposition of PBXs based on mixture of HMX and TATB was occurred in a three-steps. The first step was mainly due to decomposition of HMX. The second step was ascribed due to decomposition of TATB, while the third step was occurred due to decomposition of the polymer matrices. The thermal decomposition % was increased with increasing HMX amount. The kinetics related to thermal decomposition were investigated under non-isothermal for a single heating rate measurement. The variation in the activation energy of PBXs based on mixture of HMX and TATB was observed with varying the HMX amount. The kinetics from the results of TGA data at various heating rates under non-isothermal conditions were also calculated by Flynn—Wall—Ozawa(FWO) and Kissinger-Akahira-Sunose(KAS)methods. The activation energies calculated by employing FWO method were very close to those obtained by KAS method. The mean activation energy calculated by FWO and KAS methods was also a good agreement with the activation energy obtained from single heating rate measurement in the first step decomposition.
文摘Cross-wedge rolling (CWR) is a metal process of ro ta ry forming. To produce a part, one cylindrical billet should be placed between t wo counterrotating and wedge-shape dies, which move tangentially relative each other. The billet suffers plastic deformation (essentially, localized compressio n) during its rotation between the rotating dies. Compared to other numerical si mulation methods, the finite element method (FEM) has advantages in solving gene ral problems with complex shapes of the formed parts. In cross-wedge rolling, t here are four stages in the workpiece deformation process, namely knifing, guidi ng, stretching and sizing stage. It is time-consuming and expensive to design t he CWR process by trial and error method. The application of numerical simul ation for the CWR process will help engineers to efficiently improve the process development. Tselikov, Hayama, Jain and Kobayashi, and Higashimo applied the sl ip-line theory in study of CWR process analysis. Zb.pater studied CWR process i ncluding upsetting by upper-bound method. The above numerical simulation were b ased on the two-dimensional plain-strain assumption ignored the metal flow in workpiece axial direction. Therefore, the complex three-dimensional stress and deformation involved in CWR processes were not presented. Compared to other nume rical simulation methods, the finite element method (FEM) has advantages in solv ing general problems with complex shapes of the formed parts. As yet, a few 3-D finite element simulation studies on CWR process have been reported in literatu res. In this paper, the process of cross wedge rolling (CWR) has been simulated and analyzed by 3D rigid-plastic finite element method. Considering the charact eristic of CWR, the static implicit FEM program is selected. The models proposed in this study uses the commercial code DEFORM 3D to simulate the CWR process. T his is an implicit Lagrangian finite element code, which includes many new enhan cements functions. A new method of utilizing multiple processors using the MPI s tandard has been implemented. Automatic switching between the two different defo rmation solvers (Sparse Solver and Conjugate Gradient Solver) has also been impl emented in order to increase the speed of simulations. In this paper, all stages in CWR process are simulated to be able to closely understand and analyze the a ctual CWR process. For simulating all forming stages in CWR process, the dynam ic adaptive remeshing technology for tetrahedral solid elements was applied. T he stress distributions in cross section of forming workpiece are analyzed to in terpret fracture or rarefaction in the center of workpiece. Authors also analyze d the time-torque curve and the laws of load changing.
基金Supported by the Fund of Science and Technology Research Project of the 12th Five-year Plan(2012BAD32B02-5)
文摘In order to improve the properties of rice straw fiber film, one factor contrast test method was employed. Plasticizer type was chosen as input variable, dry tension strength and elongation, wet tension strength and elongation, bursting strength and tearing strength were chosen as indexes. The results showed that there were significant differences among the means of dry tension strength, dry elongation and bursting strength of different plasticizers; there were not significant differences among the means of wet tension strength, wet elongation and tearing strength of different plasticizers; for dry tension strength and elongation, glycerol had a significant difference with sorbitol and PEG, no significant difference was observed between sorbitol and PEG, dry tension strength added glycerol had been reduced 6.8% compared with that added sorbitol, reduced 9.5% compared with that added PEG; elongation had been improved 6.1% and 9.4%, respectively; for bursting strength, sorbitol had a significant difference with glycerol and PEG, no significant difference was observed between glycerol and PEG; bursting strength added glycerol and added PEG had been improved 6.9% and 5.6%, respectively compared with that of the added sorbitol. The results provided a theoretical reference for further improving the straw fiber film manufacturing process.
文摘The mechanical behavior of plastic concrete used in the cut-off walls of earth dams has been studied. Triaxial compression tests on the specimens in various ages and mix designs under different confining pressures have been done and the stress-strain behavior of such materials and their strength parameter changes have been experimentally investigated. It has been observed that increasing the confining pressures applied on the specimens causes the material behavior to be alike the more ductile materials and the compressive strength increases considerably as well. Moreover, a parametric study has been carded out to investigate the influence of essential parameters on the shear strength parameters of these materials. According to the research, increasing the coarse to fine aggregates ratio leads to the increase of compressive strength of the specimens as well as the increase of the cohesion and internal friction angle of the materials. Furthermore, the bentonite content decrease and the cement factor increase result in an increase of the cohesion parameter of plastic concretes and decrease of the internal friction angle of such materials.
