Two methods of preparation of the organometallic precursor[188Re(CO)3(H2O)3]+ in aqueous were present in this paper.One method uses gaseous carbon monoxide and amine borane(BH3·NH3) as the reducing agent.In other...Two methods of preparation of the organometallic precursor[188Re(CO)3(H2O)3]+ in aqueous were present in this paper.One method uses gaseous carbon monoxide and amine borane(BH3·NH3) as the reducing agent.In other method,CO(g) is replaced by K2[H3BCO2]that releases carbon monoxide during hydrolysis.Both procedures were prepared as radiolabled kits,affording the desired precursor in yields 85% after 20 min at 75 °C.The routine kit-preparation of the precursor[188Re(CO)3(H2O)3]+ in combination with tailor-made ligand systems enables the organometallic labeling of biomolecules with unprecedented high specific activities.展开更多
文摘Two methods of preparation of the organometallic precursor[188Re(CO)3(H2O)3]+ in aqueous were present in this paper.One method uses gaseous carbon monoxide and amine borane(BH3·NH3) as the reducing agent.In other method,CO(g) is replaced by K2[H3BCO2]that releases carbon monoxide during hydrolysis.Both procedures were prepared as radiolabled kits,affording the desired precursor in yields 85% after 20 min at 75 °C.The routine kit-preparation of the precursor[188Re(CO)3(H2O)3]+ in combination with tailor-made ligand systems enables the organometallic labeling of biomolecules with unprecedented high specific activities.
