Drying technology of angiotensin converting enzyme (ACE) inhibitory peptides derived from bovine casein was investigated. No significance was observed on ACE inhibitory activity of products prepared by spay drying a...Drying technology of angiotensin converting enzyme (ACE) inhibitory peptides derived from bovine casein was investigated. No significance was observed on ACE inhibitory activity of products prepared by spay drying and freeze drying (P〉0.05). Spay drying was the best drying process for practical industry production. The inlet temperature ranged from 140℃ to 160℃ and the exit temperature ranged from 70 ℃ to 90 ℃ during the spay drying process. Under the optimal conditions, scale-up of angiotensin converted enzyme inhibitory peptide from 1 L to 10 L and the experiment was successively conducted. Peptide yield was 29% and half inhibitory concentration (IC50) was 0.53 g. L^-1.展开更多
An adaptive chaotic gradient descending optimization algorithm for single objective optimization was presented. A local minimum judged by two rules was obtained by an improved mutative-step gradient descending method....An adaptive chaotic gradient descending optimization algorithm for single objective optimization was presented. A local minimum judged by two rules was obtained by an improved mutative-step gradient descending method. A new optimal minimum was obtained to replace the local minimum by mutative-scale chaotic search algorithm whose scales are magnified gradually from a small scale in order to escape local minima. The global optimal value was attained by repeatedly iterating. At last, a BP (back-propagation) neural network model for forecasting slag output in matte converting was established. The algorithm was used to train the weights of the BP neural network model. The simulation results with a training data set of 400 samples show that the training process can be finished within 300 steps to obtain the global optimal value, and escape local minima effectively. An optimization system for operation parameters, which includes the forecasting model, is achieved, in which the output of converter increases by 6.0%, and the amount of the treated cool materials rises by 7.8% in the matte converting process.展开更多
Most of China's wetland areas are located in Sanjiang Plain (Three River Basin). It's area has 207×104 hm2 of wet and low-lying farmland, of which 59% is cropped. During 1970s and 1980s, the Chinese gover...Most of China's wetland areas are located in Sanjiang Plain (Three River Basin). It's area has 207×104 hm2 of wet and low-lying farmland, of which 59% is cropped. During 1970s and 1980s, the Chinese government organized intensive scientific research into potential changes to existing natural resources conditions for this farmland. The aim was to make the water resources regime beneficial to crop production. Arterial drainage, field drainage and appropriate sub-soil treatments were suggested. The Four Waters converting mechanism and the estimation of the Four Water converting amount in wet and low-lying farmland were discussed in the paper.展开更多
Most of China's wetland areas are located in the Sanjiang Plain.This area has 207×10 4 hm 2 of wet and low lying farmland,of which 59% is cropped.During the 1970s and 1980s,the Chinese government organize...Most of China's wetland areas are located in the Sanjiang Plain.This area has 207×10 4 hm 2 of wet and low lying farmland,of which 59% is cropped.During the 1970s and 1980s,the Chinese government organized intensive scientific research into potential changes to existing natural resources conditions for these farmlands.The aim was to change the water resources regime to one that was beneficial to crop production.Arterial drainage,field drainage and appropriate sub soil treatments were required.The relation between plant products industry and the Four Waters distribution,also the main measures of the Four Waters converting in wet and low lying farmland were discussed in the paper.展开更多
With deep research into apoptosis recently,malignancy has been recognized to result not only fromenhanced cell proliferation but also from decreasedphysiological programmed cell death (apoptosis).Interleukin-l β conv...With deep research into apoptosis recently,malignancy has been recognized to result not only fromenhanced cell proliferation but also from decreasedphysiological programmed cell death (apoptosis).Interleukin-l β converting enzyme (ICE) gene, ahomologue of the Caenorhabiditis elegans ce1l death geneced-3, has been identified as a key inducer of apoptosis inmammalian cells. However, no study of ICE genetherapy on cancer has been reported up to now. Weconstructed recombinant retroviral vectors with展开更多
A fast generation method of fuzzy rules for flux optimization decision-making was proposed in order to extract the linguistic knowledge from numerical data in the process of matter converting. The fuzzy if-then rules ...A fast generation method of fuzzy rules for flux optimization decision-making was proposed in order to extract the linguistic knowledge from numerical data in the process of matter converting. The fuzzy if-then rules with consequent real number were extracted from numerical data, and a linguistic representation method for deriving linguistic rules from fuzzy if-then rules with consequent real numbers was developed. The linguistic representation consisted of The simulat two linguistic variables with the degree of certainty and the storage structure of rule base was described. on results show that the method involves neither the time-consuming iterative learning procedure nor the complicated rule generation mechanisms, and can approximate complex system. The method was applied to determine the flux amount of copper converting furnace in the process of matter converting. The real result shows that the mass fraction of Cu in slag is reduced by 0.5 %.展开更多
This paper investigates the attitude tracking control problem for the cruise mode of a dual-system convertible unmanned aerial vehicle(UAV)in the presence of parameter uncertainties,unmodeled uncertainties and wind di...This paper investigates the attitude tracking control problem for the cruise mode of a dual-system convertible unmanned aerial vehicle(UAV)in the presence of parameter uncertainties,unmodeled uncertainties and wind disturbances.First,a fixed-time disturbance observer(FXDO)based on the bi-limit homogeneity theory is designed to estimate the lumped disturbance of the convertible UAV model.Then,a fixed-time integral sliding mode control(FXISMC)is combined with the FXDO to achieve strong robustness and chattering reduction.Bi-limit homogeneity theory and Lyapunov theory are applied to provide detailed proof of the fixed-time stability.Finally,numerical simulation experimental results verify the robustness of the proposed algorithm to model parameter uncertainties and wind disturbances.In addition,the proposed algorithm is deployed in a open-source UAV autopilot and its effectiveness is further demonstrated by hardware-in-the-loop experimental results.展开更多
To facilitate rapid analysis of the oscillation stability mechanism in modular multilevel converter-based high voltage direct current(MMC-HVDC)systems and streamline the simulation process for determining MMC impedanc...To facilitate rapid analysis of the oscillation stability mechanism in modular multilevel converter-based high voltage direct current(MMC-HVDC)systems and streamline the simulation process for determining MMC impedance characteristics,a simplified mathematical simulation model for MMC closed-loop impedance is developed using the harmonic state space method.This model considers various control strategies and includes both AC-side and DC-side impedance models.By applying a Nyquist criterion-based impedance analysis method,the stability mechanisms on the AC and DC sides of the MMC are examined.In addition,a data-driven oscillation stability analysis method is also proposed,leveraging a global sensitivity algorithm based on fast model results to identify key parameters influencing MMC oscillation stability.Based on sensitivity analysis results,a parameter adjustment strategy for oscillation suppression is proposed.The simulation results from the MATLAB/Simulinkbased MMC model validate the effectiveness of the proposed method.展开更多
基金Supported by Scientific Research Foundation for Young Scholars of Heilongjiang Province of China (QC07C25)The National High Technology Research and Development Program of China (2008AA10Z315)
文摘Drying technology of angiotensin converting enzyme (ACE) inhibitory peptides derived from bovine casein was investigated. No significance was observed on ACE inhibitory activity of products prepared by spay drying and freeze drying (P〉0.05). Spay drying was the best drying process for practical industry production. The inlet temperature ranged from 140℃ to 160℃ and the exit temperature ranged from 70 ℃ to 90 ℃ during the spay drying process. Under the optimal conditions, scale-up of angiotensin converted enzyme inhibitory peptide from 1 L to 10 L and the experiment was successively conducted. Peptide yield was 29% and half inhibitory concentration (IC50) was 0.53 g. L^-1.
文摘An adaptive chaotic gradient descending optimization algorithm for single objective optimization was presented. A local minimum judged by two rules was obtained by an improved mutative-step gradient descending method. A new optimal minimum was obtained to replace the local minimum by mutative-scale chaotic search algorithm whose scales are magnified gradually from a small scale in order to escape local minima. The global optimal value was attained by repeatedly iterating. At last, a BP (back-propagation) neural network model for forecasting slag output in matte converting was established. The algorithm was used to train the weights of the BP neural network model. The simulation results with a training data set of 400 samples show that the training process can be finished within 300 steps to obtain the global optimal value, and escape local minima effectively. An optimization system for operation parameters, which includes the forecasting model, is achieved, in which the output of converter increases by 6.0%, and the amount of the treated cool materials rises by 7.8% in the matte converting process.
文摘Most of China's wetland areas are located in Sanjiang Plain (Three River Basin). It's area has 207×104 hm2 of wet and low-lying farmland, of which 59% is cropped. During 1970s and 1980s, the Chinese government organized intensive scientific research into potential changes to existing natural resources conditions for this farmland. The aim was to make the water resources regime beneficial to crop production. Arterial drainage, field drainage and appropriate sub-soil treatments were suggested. The Four Waters converting mechanism and the estimation of the Four Water converting amount in wet and low-lying farmland were discussed in the paper.
文摘Most of China's wetland areas are located in the Sanjiang Plain.This area has 207×10 4 hm 2 of wet and low lying farmland,of which 59% is cropped.During the 1970s and 1980s,the Chinese government organized intensive scientific research into potential changes to existing natural resources conditions for these farmlands.The aim was to change the water resources regime to one that was beneficial to crop production.Arterial drainage,field drainage and appropriate sub soil treatments were required.The relation between plant products industry and the Four Waters distribution,also the main measures of the Four Waters converting in wet and low lying farmland were discussed in the paper.
文摘With deep research into apoptosis recently,malignancy has been recognized to result not only fromenhanced cell proliferation but also from decreasedphysiological programmed cell death (apoptosis).Interleukin-l β converting enzyme (ICE) gene, ahomologue of the Caenorhabiditis elegans ce1l death geneced-3, has been identified as a key inducer of apoptosis inmammalian cells. However, no study of ICE genetherapy on cancer has been reported up to now. Weconstructed recombinant retroviral vectors with
基金Project(50374079) supported bythe National Natural Science Foundation of China project(2002cB312200) supported bythe State Key Fundamental Research and Development Programof China
文摘A fast generation method of fuzzy rules for flux optimization decision-making was proposed in order to extract the linguistic knowledge from numerical data in the process of matter converting. The fuzzy if-then rules with consequent real number were extracted from numerical data, and a linguistic representation method for deriving linguistic rules from fuzzy if-then rules with consequent real numbers was developed. The linguistic representation consisted of The simulat two linguistic variables with the degree of certainty and the storage structure of rule base was described. on results show that the method involves neither the time-consuming iterative learning procedure nor the complicated rule generation mechanisms, and can approximate complex system. The method was applied to determine the flux amount of copper converting furnace in the process of matter converting. The real result shows that the mass fraction of Cu in slag is reduced by 0.5 %.
基金supported by National Natural Science Foundation of China (Grant Nos.52072309 and 62303379)Beijing Institute of Spacecraft System Engineering Research Project (Grant NO.JSZL2020203B004)+1 种基金Natural Science Foundation of Shaanxi Province,Chinese (Grant NOs.2023-JC-QN-0003 and 2023-JC-QN-0665)Industry-University-Research Innovation Fund of Ministry of Education for Chinese Universities (Grant NO.2022IT189)。
文摘This paper investigates the attitude tracking control problem for the cruise mode of a dual-system convertible unmanned aerial vehicle(UAV)in the presence of parameter uncertainties,unmodeled uncertainties and wind disturbances.First,a fixed-time disturbance observer(FXDO)based on the bi-limit homogeneity theory is designed to estimate the lumped disturbance of the convertible UAV model.Then,a fixed-time integral sliding mode control(FXISMC)is combined with the FXDO to achieve strong robustness and chattering reduction.Bi-limit homogeneity theory and Lyapunov theory are applied to provide detailed proof of the fixed-time stability.Finally,numerical simulation experimental results verify the robustness of the proposed algorithm to model parameter uncertainties and wind disturbances.In addition,the proposed algorithm is deployed in a open-source UAV autopilot and its effectiveness is further demonstrated by hardware-in-the-loop experimental results.
基金National Natural Science Foundation of China(52307127)State Key Laboratory of Power System Operation and Control(SKLD23KZ07)。
文摘To facilitate rapid analysis of the oscillation stability mechanism in modular multilevel converter-based high voltage direct current(MMC-HVDC)systems and streamline the simulation process for determining MMC impedance characteristics,a simplified mathematical simulation model for MMC closed-loop impedance is developed using the harmonic state space method.This model considers various control strategies and includes both AC-side and DC-side impedance models.By applying a Nyquist criterion-based impedance analysis method,the stability mechanisms on the AC and DC sides of the MMC are examined.In addition,a data-driven oscillation stability analysis method is also proposed,leveraging a global sensitivity algorithm based on fast model results to identify key parameters influencing MMC oscillation stability.Based on sensitivity analysis results,a parameter adjustment strategy for oscillation suppression is proposed.The simulation results from the MATLAB/Simulinkbased MMC model validate the effectiveness of the proposed method.