期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
Molecular pathogenetic mechanism of maternally inherited deafness 被引量:6
1
作者 GUAN Min - XinDivision and Program in Human Genetics and Center for Hearing and Deafaess Research,Cincinnati Children’s Hospital Medical Center, and Department of Pediatrics, Universityof Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA 《中华耳科学杂志》 CSCD 2003年第3期49-57,共9页
关键词 MTDNA in is et of molecular pathogenetic mechanism of maternally inherited deafness RRNA
在线阅读 下载PDF
Oxidized low density lipoprotein (Ox-LDL) impacts on erythrocyte viscoelasticity and its molecular mechanism 被引量:1
2
作者 K.-L.Paul Sung Lanping Amy Sung 《医用生物力学》 EI CAS CSCD 2009年第S1期60-60,共1页
Aim:The oxidized low-density lipoprotein(OxLDL) plays an important role in atherosclerosis yet it remains unclear if it damages circulating erythrocytes. Method: In this study。
关键词 OX-LDL impacts on erythrocyte viscoelasticity and its molecular mechanism Oxidized low density lipoprotein
在线阅读 下载PDF
Germplasm Evaluation,Inheritance, Molecular Marker and Mechanism of Resistance to Frog eye Leaf Spot
3
作者 YANG Qingkai (Soybean Research Institute,Northeast Agricultural University, Harbin 150030,P.R.China) 《Journal of Northeast Agricultural University(English Edition)》 CAS 2000年第1期1-6,共6页
Soybean frog eye leaf spot(FLS) has been a major disease and production constralnt in the Northeast of China.The paper reported methods for identifying and evaluating resistant germplasm to the disease,at sometime li... Soybean frog eye leaf spot(FLS) has been a major disease and production constralnt in the Northeast of China.The paper reported methods for identifying and evaluating resistant germplasm to the disease,at sometime listed several resistant cultivars or lines which were resistant to both dominant races (1,7 race)and the mixture of over 8 races. It indicated that the resistance to race 1 or 7 were due to two different single dominant genes,respectively.And in the fied,there were more races,the resistance showed quantitative character.It was proposed the LTP,which was made according to the sizeand number of lesions could be used as an important index in selecting. Using bulked segregants analysis (BSA),the genetic distance between OPSO3 620 and resistant gene to race 7 were identified 8.7cm.The results showed that the resistant cultivars had less number of stoma,closer arrangement of polisade tissue and high cotent of wax. 展开更多
关键词 SOYBEAN resistant germeplasm resistant heridity molecular marker resistance mechanism
在线阅读 下载PDF
无底物情况下来自Rhodococcus zopfii的腈水解酶中亲核进攻试剂CYS165的活性状态的探究(英文)
4
作者 张慧珠 高旭丹 梅晔 《南京大学学报(自然科学版)》 北大核心 2025年第1期129-139,共11页
腈水解酶作为一类在工业应用中具有巨大价值的绿色生物催化剂,能够高效地催化腈基化合物转化为羧酸.尽管其应用广泛,但腈水解酶的具体催化机制仍然不明确.先前的研究揭示了腈水解酶活性中心的GLU-LYS-GLU-CYS四联体在催化中起到关键作用... 腈水解酶作为一类在工业应用中具有巨大价值的绿色生物催化剂,能够高效地催化腈基化合物转化为羧酸.尽管其应用广泛,但腈水解酶的具体催化机制仍然不明确.先前的研究揭示了腈水解酶活性中心的GLU-LYS-GLU-CYS四联体在催化中起到关键作用,其中CYS残基作为亲核试剂攻击腈基,其硫醇基团的电离是反应中的一个关键步骤,然而,CYS的去质子化过程尚未被清晰揭示.研究聚焦于来自Rhodococcus zopfii(RzNIT)的腈水解酶,并研究了底物尚未进入酶活性位点时CYS165的质子化状态.通过对CYS165去质子化可能路径的详细分析,确认了在无底物状态下RzNIT中的CYS165处于中性状态.这一发现为进一步研究RzNIT的催化机制奠定了基础. 展开更多
关键词 ONIOM(the Own n-Layered Integrated molecular Orbital and molecular Mechanics) 腈水解酶 能垒 催化机制
在线阅读 下载PDF
A review of the pathogenicity mechanism of Verticillium dahliae in cotton 被引量:8
5
作者 ZHANG Yalin ZHOU Jinglong +5 位作者 ZHAO Lihong FENG Zili WEI Feng BAI Hongyan FENG Hongjie ZHU Heqin 《Journal of Cotton Research》 2022年第1期59-71,共13页
Verticillium wilt,caused by the notorious fungal pathogen Verticillium dahliae,is one of the main limiting factors for cotton production.Due to the stable dormant structure microsclerotia,long-term variability and co-... Verticillium wilt,caused by the notorious fungal pathogen Verticillium dahliae,is one of the main limiting factors for cotton production.Due to the stable dormant structure microsclerotia,long-term variability and co-evolution with host plant,its pathogenicity mechanism is very complicated,and the interaction mechanism between pathogen and host plant is also unclear.So identification and functional analysis of the genes involved in the pathogenicity or virulence of this fungus will benefit to uncover the molecular pathogenic mechanism of V.dahliae.In this review,many multifunction genes covering microsclerotia development,pathogen infection,effector proteins,transcription factors,horizontal gene transfer and trans-kingdom RNA silencing have been summarized to provide a theoretical basis to deep understand the molecular pathogenicity mechanism of V.dahliae and promote to effectively control Verticillium wilt.Furtherly,these pathogenicity-related genes may be considered as targets for effective control of Verticillium wilt in cotton. 展开更多
关键词 Verticillium dahliae COTTON Pathogenicity-related genes molecular pathogenic mechanism
在线阅读 下载PDF
Overview of Plant Shooting Branch
6
作者 Jin Feng Li Yuan Hu Bao-zhong 《Journal of Northeast Agricultural University(English Edition)》 CAS 2012年第2期74-85,共12页
The development of plant branching plays a pivotal role in the morphogenesis of plants. It is affected by the genes and also by the environment. Recent studies of plant branching had made great progresses in the devel... The development of plant branching plays a pivotal role in the morphogenesis of plants. It is affected by the genes and also by the environment. Recent studies of plant branching had made great progresses in the development of the branch control of the physiology, biochemistry, functional genomics, comparative genomics and other aspects. Moreover, we got many mutants associated with the branch development from pea, Arabidopsis, petunia, rice, tomato and corn, such as the formation of axillary meristem-related revoluta (rev), pinhead, monoculml (mocl), laterral suppressor (ls), blind/torosa and other mutants. Preliminary study showed that the formation of meristem development was controlled by regulating hormones and transcription factor interaction network, but the development was both conservative and distinctive in different Mycobacterium species 展开更多
关键词 branching axillary meristem AUXIN CYTOKININ molecular mechanism
在线阅读 下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部