To address the issues for assessing and prospecting the replaceable resource of crisis mines, a geological ore-controlling field model and a mineralization distribution field model were proposed from the viewpoint of ...To address the issues for assessing and prospecting the replaceable resource of crisis mines, a geological ore-controlling field model and a mineralization distribution field model were proposed from the viewpoint of field analysis. By dint of solving the field models through transferring the continuous models into the discrete ones, the relationship between the geological ore-controlling effect field and the mineralization distribution field was analyzed, and the quantitative and located parameters were extracted for describing the geological factors controlling mineralization enrichment. The method was applied to the 3-dimensional localization and quantitative prediction for concealed ore bodies in the depths and margins of the Daehang mine in Guangxi, China, and the 3-dimensional distribution models of mineralization indexes and ore-controlling factors such as magmatic rocks, strata, faults, lithology and folds were built. With the methods of statistical analysis and the non-linear programming, the quantitative index set of the geological ore-controlling factors was obtained. In addition, the stereoscopic located and quantitative prediction models were set up by exploring the relationship between the mineralization indexes and the geological ore-controlling factors. So far, some concealed ore bodies with the resource volume of a medium-sized mineral deposit are found in the deep parts of the Dachang Mine by means of the deep prospecting drills following the prediction results, from which the effectiveness of the predication models and results is proved.展开更多
目的研究长春市35~79岁汉族人群维生素D受体基因BsmⅠ、FokⅠ位点多态性的分布特征及其与腰椎骨密度(bone mineral density,BMD)的相关性,分析不同基因型对骨代谢的调节与影响,同时研究血清TGF-β、TRACP水平与腰椎BMD的相关性,为骨质...目的研究长春市35~79岁汉族人群维生素D受体基因BsmⅠ、FokⅠ位点多态性的分布特征及其与腰椎骨密度(bone mineral density,BMD)的相关性,分析不同基因型对骨代谢的调节与影响,同时研究血清TGF-β、TRACP水平与腰椎BMD的相关性,为骨质疏松预防、早期诊断和治疗提供分子生物学依据。方法应用Hologic Discovery WA型骨密度仪检测腰椎正位(L1-L4)BMD;采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)分析BsmⅠ和FokⅠ位点多态性;采用酶联免疫吸附分析法检测血清TGF-β、TRACP水平;采用SPSS 23.0软件进行统计分析。结果在500名汉族人群中,BsmⅠ位点基因型以bb型为主,占80.2%,Bb型占15.2%,BB型占4.6%;FokⅠ位点ff基因型占18.6%,Ff型占45.8%,FF型占35.6%。BsmⅠ位点各基因型骨质疏松组与非骨质疏松组分布特征组间差异无统计学意义(P>0.05);FokⅠ位点ff基因型骨质疏松组所占比例高于非骨质疏松组,差异有统计学意义(P<0.05)。BsmⅠ位点bb基因型男性、女性BMD值均低于Bb型和BB型,但差异无统计学意义(P>0.05);FokⅠ位点ff基因型男性、女性BMD值均低于Ff型和FF型,差异有统计学意义(P<0.05)。血清TGF-β水平骨质疏松组显著低于非骨质疏松组,而TRACP水平骨质疏松组高于非骨质疏松组,组间差异有统计学意义(P<0.05)。结论本研究500名汉族人群中,BsmⅠ位点以bb基因型为主,占80.2%,各基因型骨密度值组间差异无统计学意义;FokⅠ位点ff型BMD值低于Ff型和FF型,骨质疏松组ff基因型所占比例高于非骨质疏松组,差异有统计学意义,提示ff基因型可能是骨质疏松发生的危险因素;骨质疏松组血清TGF-β水平显著低于非骨质疏松组,而TRACP水平高于非骨质疏松组,差异有统计学意义,表明TGF-β、TRACP是评价骨代谢状态的良好指标。展开更多
为研究煤矿工人职业健康的发展趋势,促进煤炭企业实施职业健康防护工作,基于知识图谱分析方法,采用CiteSpace软件分析中国知网(CNKI)和Web of Science(WoS)核心数据库中收录的近20年煤矿工人职业健康文献的关键词聚类及突现。研究结果表...为研究煤矿工人职业健康的发展趋势,促进煤炭企业实施职业健康防护工作,基于知识图谱分析方法,采用CiteSpace软件分析中国知网(CNKI)和Web of Science(WoS)核心数据库中收录的近20年煤矿工人职业健康文献的关键词聚类及突现。研究结果表明:煤矿工人职业健康研究可分为职业健康危害因素、职业病及职业相关疾病三维度。职业相关疾病主要体现在行为和身心疾病、心脑血管疾病与代谢性疾病及慢性非特异性呼吸系统疾病3个层面;与职业病相比,职业相关疾病多呈现为“多因一果”特征,确诊难度更大;基于高频词突现特征,尘肺、听力损失、心理压力、高血压等是煤矿工人健康的主要威胁,此类健康问题与职业暴露有关,风险评价与管控是应对危害的重要措施;新兴研究热点为职业相关疾病的成因与防范,及职业健康与脑科学、智能化等领域的交叉研究。展开更多
基金Project(2007CB416608) supported by the National Basic Research Program of ChinaProject(2006BAB01B07) supported by the National Science and Technology Pillar Program during the 11th Five-Year Plan Period
文摘To address the issues for assessing and prospecting the replaceable resource of crisis mines, a geological ore-controlling field model and a mineralization distribution field model were proposed from the viewpoint of field analysis. By dint of solving the field models through transferring the continuous models into the discrete ones, the relationship between the geological ore-controlling effect field and the mineralization distribution field was analyzed, and the quantitative and located parameters were extracted for describing the geological factors controlling mineralization enrichment. The method was applied to the 3-dimensional localization and quantitative prediction for concealed ore bodies in the depths and margins of the Daehang mine in Guangxi, China, and the 3-dimensional distribution models of mineralization indexes and ore-controlling factors such as magmatic rocks, strata, faults, lithology and folds were built. With the methods of statistical analysis and the non-linear programming, the quantitative index set of the geological ore-controlling factors was obtained. In addition, the stereoscopic located and quantitative prediction models were set up by exploring the relationship between the mineralization indexes and the geological ore-controlling factors. So far, some concealed ore bodies with the resource volume of a medium-sized mineral deposit are found in the deep parts of the Dachang Mine by means of the deep prospecting drills following the prediction results, from which the effectiveness of the predication models and results is proved.
文摘为研究煤矿工人职业健康的发展趋势,促进煤炭企业实施职业健康防护工作,基于知识图谱分析方法,采用CiteSpace软件分析中国知网(CNKI)和Web of Science(WoS)核心数据库中收录的近20年煤矿工人职业健康文献的关键词聚类及突现。研究结果表明:煤矿工人职业健康研究可分为职业健康危害因素、职业病及职业相关疾病三维度。职业相关疾病主要体现在行为和身心疾病、心脑血管疾病与代谢性疾病及慢性非特异性呼吸系统疾病3个层面;与职业病相比,职业相关疾病多呈现为“多因一果”特征,确诊难度更大;基于高频词突现特征,尘肺、听力损失、心理压力、高血压等是煤矿工人健康的主要威胁,此类健康问题与职业暴露有关,风险评价与管控是应对危害的重要措施;新兴研究热点为职业相关疾病的成因与防范,及职业健康与脑科学、智能化等领域的交叉研究。
