以花生肽(相对分子质量<3.0 k D)为原料,以硫酸亚铁(Fe SO4·7H2O)为金属螯合剂,利用微波固相合成技术在单因素试验基础上,采取中心复合响应面法对花生肽亚铁配位螯合工艺进行了优化,建立了花生肽亚铁配位螯合工艺的二阶多项式...以花生肽(相对分子质量<3.0 k D)为原料,以硫酸亚铁(Fe SO4·7H2O)为金属螯合剂,利用微波固相合成技术在单因素试验基础上,采取中心复合响应面法对花生肽亚铁配位螯合工艺进行了优化,建立了花生肽亚铁配位螯合工艺的二阶多项式非线性回归方程和数值模型,分析了微波辐射时间、花生肽亚铁配体比和引发剂用量对花生肽亚铁配位螯合的影响。结果表明,最佳花生肽亚铁配位螯合工艺为:微波辐射时间153 s,花生肽亚铁配体比5∶1,引发剂(H2O)用量3%,微波辐射功率608 W,反应物粒径120目,2.5%白炭黑(占花生肽质量)为脱酸剂,0.3%异抗坏血酸钠(占硫酸亚铁质量)为亚铁保护剂。在最佳条件下螯合率为(90.68±1.31)%,与模型预测值92.71%基本吻合。研究表明,以微波固相合成技术进行花生肽亚铁固相催化制备肽金属配位螯合营养强化剂可行。展开更多
Alkyl methyl(ethyl) malonates were synthesized by solidliquid phase transfer catalysis without solvent in the new method of the reaction of potassium methyl(ethyl) malonate with alkyl bromide or chloride with high y...Alkyl methyl(ethyl) malonates were synthesized by solidliquid phase transfer catalysis without solvent in the new method of the reaction of potassium methyl(ethyl) malonate with alkyl bromide or chloride with high yields.Under the microwave irradiation,the reaction time was reduced from 2h to 2min with equal yield.展开更多
文摘Alkyl methyl(ethyl) malonates were synthesized by solidliquid phase transfer catalysis without solvent in the new method of the reaction of potassium methyl(ethyl) malonate with alkyl bromide or chloride with high yields.Under the microwave irradiation,the reaction time was reduced from 2h to 2min with equal yield.
