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Reliability analysis of modular charge swinging-loading positioning accuracy under new failure criterion based on spatial geometric relationship
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作者 Zihan Wang Linfang Qian +3 位作者 Liu Yang Taisu Liu Weiwei Chen Haolin Zhang 《Defence Technology(防务技术)》 2025年第6期115-130,共16页
The swinging-loading process is essential for automatic artillery loading systems.This study focuses on the problems of reliability analysis that affect swinging-loading positioning accuracy.A dynamic model for a mult... The swinging-loading process is essential for automatic artillery loading systems.This study focuses on the problems of reliability analysis that affect swinging-loading positioning accuracy.A dynamic model for a multi degree-of-freedom swinging-loading-integrated rigid-flexible coupling system is established.This model is based on the identification of key parameters and platform experiments.Based on the spatial geometric relationship between the breech and loader during modular charge transfer and the possible maximum interference depth of the modular charge,a new failure criterion for estimating the reliability of swinging-loading positioning accuracy is proposed.Considering the uncertainties in the operation of the pendulum loader,the direct probability integration method is introduced to analyze the reliability of the swinging-loading positioning accuracy under three different charge numbers.The results indicate that under two and four charges,the swinging-loading process shows outstanding reliability.However,an unstable stage appears when the swinging motion occurred under six charges,with a maximum positioning failure probability of 0.0712.A comparison between the results obtained under the conventional and proposed criteria further reveals the effectiveness and necessity of the proposed criterion. 展开更多
关键词 Artillery loading system Pendulum loader Dynamic model Failure criterion Reliability analysis
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Catastrophe model and its experimental verification ofstatic loading rock system under impact load 被引量:2
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作者 左宇军 李夕兵 +3 位作者 王卫华 张义平 马春德 闫长斌 《Journal of Central South University of Technology》 EI 2006年第3期281-285,共5页
According to the catastrophe model for impact buckling of static loading structures, a new catastrophe model for impact loading failure of a static loading rock system was established, and one dimension (1D) catastrop... According to the catastrophe model for impact buckling of static loading structures, a new catastrophe model for impact loading failure of a static loading rock system was established, and one dimension (1D) catastrophe model was analyzed. The analysis results indicate that the furcation collection where catastrophe may take place is not only decided by mechanical system itself but also relates to exterior loading, which is different from the results obtained under mono-static loading where the bifurcation collection is only determined by mechanics of the system itself and has nothing to do with exterior loading. In addition, the corresponding 1D coupled static-dynamic loading experiment is designed to verify the analysis results of catastrophe model. The test is done with Instron 1342 electro-servo controlled testing system, in which medium strain rate is caused by monotony rising dynamic load. The parameters are obtained combining theoretical model with experiment. The experimental and theoretical curves of critical dynamic load vs static load are rather coincided, thus the new model is proved to be correct. 展开更多
关键词 static loading rock system impact load INSTABILITY catastrophic model coupled static-dynamic loading
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Low complexity bit loading algorithm for OFDM system 被引量:1
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作者 Yang Yu Sha Xuejun Zhang Zhonghua 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第1期71-74,共4页
A new approach to loading for orthogonal frequency division multiplexing (OFDM) system is proposed, this bit-loading algorithm assigns bits to different subchannels in order to minimize the transmit energy. In the a... A new approach to loading for orthogonal frequency division multiplexing (OFDM) system is proposed, this bit-loading algorithm assigns bits to different subchannels in order to minimize the transmit energy. In the algorithm, first most bit are allocated to each subchannels according to channel condition, Shannon formula and QoS require of the user, then the residual bit are allocated to the subchannels bit by bit. In this way the algorithm is efficient while calculation is less complex. This is the first time to load bits with the scale following Shannon formula and the algorithm is of O (4 N) complexity. 展开更多
关键词 OFDM bit loading Shannon formula QOS
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Adaptive bit and power loading algorithm with low complexity in MIMO-OFDM systems
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作者 Huo Yongqing Peng Qicong Shao Huaizong 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2008年第3期461-466,共6页
Two adaptive power and bit loading algorithms to maximize the throughput of MIMO-OFDM systems in frequency selective fading environment are proposed. The two algorithms allocate bit based on maximizing the overall thr... Two adaptive power and bit loading algorithms to maximize the throughput of MIMO-OFDM systems in frequency selective fading environment are proposed. The two algorithms allocate bit based on maximizing the overall throughput. One algorithm allocates power based on guaranteeing that the bit error rate (BER) of each sub-carrier and the total allocated power remain below a target BER threshold and a power threshold, respectively; another one allocates power based on guaranteeing that the mean BER of sub-carriers and the total allocated power remain below a target BER threshold and a power threshold, respectively. The simulation results show that the proposed algorithms can achieve faster throughput with lower computational complexity, which indicates that the proposed algorithms are effective when compared to some existing algorithms. 展开更多
关键词 MIMO-OFDM adaptive loading THROUGHPUT BER.
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Damage evolution and failure behavior of coal-rock combination subjected to different cyclic loading paths and loading rates: Insights from energy-driven effects
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作者 WANG Kai ZUO Xiao-huan +4 位作者 DU Feng SUN Jia-zhi JU Yang SHU Long-yong CAI Yong-bo 《Journal of Central South University》 2025年第9期3447-3469,共23页
In this study,a uniaxial cyclic compression test is conducted on coal-rock composite structures under two cyclic loads using MTSE45.104 testing apparatus to investigate the macro-mesoscopic deformation,damage behavior... In this study,a uniaxial cyclic compression test is conducted on coal-rock composite structures under two cyclic loads using MTSE45.104 testing apparatus to investigate the macro-mesoscopic deformation,damage behavior,and energy evolution characteristics of these structures under different cyclic stress disturbances.Three loading and unloading rates(LURs)are tested to examine the damage behaviors and energy-driven characteristics of the composites.The findings reveal that the energy-driven behavior,mechanical properties,and macro-micro degradation characteristics of the composites are significantly influenced by the loading rate.Under the gradual cyclic loading and unloading(CLU)path with a constant lower limit(path I)and the CLU path with variable upper and lower boundaries(path II),an increase in LURs from 0.05 to 0.15 mm/min reduces the average loading time by 32.39%and 48.60%,respectively.Consequently,the total number of cracks in the samples increases by 1.66-fold for path I and 1.41-fold for path II.As LURs further increase,the energy storage limit of samples expands,leading to a higher proportion of transmatrix and shear cracks.Under both cyclic loading conditions,a broader cyclic stress range promotes energy dissipation and the formation of internal fractures.Notably,at higher loading rates,cracks tend to propagate along primary weak surfaces,leading to an increased incidence of intermatrix fractures.This behavior indicates a microscopic feature of the failure mechanisms in composite structures.These results provide a theoretical basis for elucidating the damage and failure characteristics of coal-rock composite structures under cyclic stress disturbances. 展开更多
关键词 coal-rock composite samples cyclic loading loading and unloading rates RA-AF correlation macro-micro damage features failure behavior
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Effect of loading rate on the mechanical response and energy evolution of skarn rock subjected to constant-amplitude cyclic loading
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作者 WU Yun-feng WANG Yu +5 位作者 LI Chang-hong ZHOU Bao-kun LI Peng CAI Mei-feng SUN Chang-kun TIAN Zi-cheng 《Journal of Central South University》 2025年第3期1117-1140,共24页
This work aims to reveal the mechanical responses and energy evolution characteristics of skarn rock under constant amplitude-varied frequency loading paths.Testing results show that the fatigue lifetime,stress−strain... This work aims to reveal the mechanical responses and energy evolution characteristics of skarn rock under constant amplitude-varied frequency loading paths.Testing results show that the fatigue lifetime,stress−strain responses,deformation,energy dissipation and fracture morphology are all impacted by the loading rate.A pronounced influence of the loading rate on rock deformation is found,with slower loading rate eliciting enhanced strain development,alongside augmented energy absorption and dissipation.In addition,it is revealed that the loading rate and cyclic loading amplitude jointly influence the phase shift distribution,with accelerated rates leading to a narrower phase shift duration.It is suggested that lower loading rate leads to more significant energy dissipation.Finally,the tensile or shear failure modes were intrinsically linked to loading strategy,with cyclic loading predominantly instigating shear damage,as manifest in the increased presence of pulverized grain particles.This work would give new insights into the fortification of mining structures and the optimization of mining methodologies. 展开更多
关键词 cyclic loading loading rate constant amplitude deformation characteristics energy dissipation
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Strength and failure characteristics of hard rock containing a single structural plane under varied loading angles : A true triaxial investigation
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作者 XU Huai-sheng LI Shao-jun +3 位作者 XU Ding-ping LIU Xu-feng FENG Guang-liang WANG Zhao-feng 《Journal of Central South University》 2025年第5期1903-1921,共19页
The spatial relationship between structural planes and principal stresses significantly affects the mechanical properties of deep hard rock.This paper examines the effect of the loading angle under true triaxial compr... The spatial relationship between structural planes and principal stresses significantly affects the mechanical properties of deep hard rock.This paper examines the effect of the loading angle under true triaxial compression.While previous studies focused on the angleβbetween the maximum principal stress and the structural plane,the role of angleω,between the intermediate principal stress and the structural plane,is often overlooked.Utilizing artificially prefabricated granite specimens with a single non-penetrating structural plane,we set the loading angleβto range from 0°to 90°across seven groups,and assignedωvalues of 0°and 90°in two separate groups.The results show that the peak strength is negatively correlated withβup to 45°,beyond which it tends to stabilize.The angleωexerts a strengthening effect on the peak strength.Deformation mainly occurs post-peak,with the strain values ε_(1) and ε_(3) reaching levels 2−3 times higher than those in intact rock.The structural plane significantly influences failure mode whenω=0°,while failure localizes near the σ_(3) surface of the specimens whenω=90°.The findings enhance data on structural plane rocks under triaxial compression and inform theoretical research,excavation,and support design of rock structures. 展开更多
关键词 true triaxial compression hard rock structural plane loading angle STRENGTH failure characteristics
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Equivalent loading method for the thin-walled floors of armored vehicles with bottom explosion impacts
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作者 Weiwei Qin Jiahao He +6 位作者 Shaoyan Zhang Tuzao Yao Jing Tang Xianhui Wang Xiaowang Sun Tao Wang Qiang Zhou 《Defence Technology(防务技术)》 2025年第10期184-206,共23页
The high cost and low efficiency of full-scale vehicle experiments and numerical simulations limit the efficient development of armored vehicle occupant protection systems.The floor-occupant-seat local simulation mode... The high cost and low efficiency of full-scale vehicle experiments and numerical simulations limit the efficient development of armored vehicle occupant protection systems.The floor-occupant-seat local simulation model provides an alternative solution for quickly evaluating the performance of occupant protection systems.However,the error and rationality of the loading of the thin-walled floor in the local model cannot be ignored.This study proposed an equivalent loading method for the local model,which includes two parts:the dimensionality reduction method for acceleration matrix and the joint optimization framework for equivalent node coordinates.In the dimensionality reduction method,the dimension of the acceleration matrix was reduced based on the improved kernel principal component analysis(KPCA),and a dynamic variable bandwidth was introduced to address the limitation of failing to effectively measure the similarity between acceleration data in conventional KPCA.In addition,a least squares problem with forced displacement constraints was constructed to solve the correction matrix,thereby achieving the scale restoration process of the principal component acceleration matrix.The joint optimization framework for coordinates consists of the error assessment of response time histories(EARTH)and Bayesian optimization.In this framework,the local loading error of the equivalent acceleration matrix is taken as the Bayesian optimization objective,which is quantified and scored by EARTH.The expected improvement acquisition function was used to select the new set of the equivalent acceleration node coordinates for the self-updating optimization of the observation dataset and Gaussian process surrogate model.We reduced the dimension of the acceleration matrix from 2256 to 7,while retaining 91%of the information features.The comprehensive error score of occupant's lower limb response in the local model increased from 58.5%to 80.4%.The proposed equivalent loading method provides a solution for the rapid and reliable development of occupant protection systems. 展开更多
关键词 Armored vehicles Local model Equivalent loading Dimensionality reduction Bayes optimization
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A fast-running engineering tool for assessing structural vulnerability to blast loading
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作者 Carlo Crispino Salvatore Annunziata +2 位作者 Alberto Contini Luca Lomazzi Andrea Manes 《Defence Technology(防务技术)》 2025年第4期244-254,共11页
Assessing the vulnerability of a platform is crucial in its design.In fact,the results obtained from vulnerability analyses provide valuable information,leading to precise design choices or corrective solutions that e... Assessing the vulnerability of a platform is crucial in its design.In fact,the results obtained from vulnerability analyses provide valuable information,leading to precise design choices or corrective solutions that enhance the platform's chances of surviving different scenarios.Such scenarios can involve various types of threats that can affect the platform's survivability.Among such,blast waves impacting the platform's structure represent critical conditions that have not yet been studied in detail.That is,frameworks for vulnerability assessment that can deal with blast loading have not been presented yet.In this context,this work presents a fast-running engineering tool that can quantify the risk that a structure fails when it is subjected to blast loading from the detonation of high explosive-driven threats detonating at various distances from the structure itself.The tool has been implemented in an in-house software that calculates vulnerability to various impacting objects,and its capabilities have been shown through a simplified,yet realistic,case study.The novelty of this research lies in the development of an integrated computational environment capable of calculating the platform's vulnerability to blast waves,without the need for running expensive finite element simulations.In fact,the proposed tool is fully based on analytical models integrated with a probabilistic approach for vulnerability calculation. 展开更多
关键词 VULNERABILITY Blast loading Probabilistic assessment Analytical models Fast-running engineering tool
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Damage evolution in sandstone under uniaxial cyclic loading and varying water contents:Theoretical and experimental investigation
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作者 ZHANG Sheng BAI Wei +3 位作者 XU Ding-ping ZHENG Hong JIANG Quan LI Zhi-wei 《Journal of Central South University》 2025年第8期3095-3110,共16页
During underground excavation,the surrounding rock mass is subjected to complex cyclic stress,significantly impacting its long-term stability,especially under varying water content conditions where this effect is ampl... During underground excavation,the surrounding rock mass is subjected to complex cyclic stress,significantly impacting its long-term stability,especially under varying water content conditions where this effect is amplified.However,research on the mechanical response mechanisms of surrounding rock mass under such conditions remains inadequate.This study utilized acoustic emission(AE)and resistivity testing to monitor rock fracture changes,revealing the rock’s damage state and characterizing the damage evolution process during uniaxial cyclic loading and unloading.First,a damage variable equation was established based on AE and resistivity parameters,leading to the derivation of a corresponding damage constitutive equation.Uniaxial cyclic loading and unloading tests were then conducted on sandstone samples with varying water contents,continuously monitoring AE signals and resistivity,along with computed tomography scans before and after failure.The predictions from the damage constitutive equation were compared with experimental results.This comparison shows that the proposed damage variable equation effectively characterizes the damage evolution of sandstone during loading and unloading,and that the constitutive equation closely fits the experimental data.This study provides a theoretical basis for monitoring and assessing the responses of surrounding rock mass during underground excavation. 展开更多
关键词 SANDSTONE acoustic emission rock resistivity uniaxial cyclic loading and unloading rock cracks damage constitutive equation
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Interfacial thermal contact model for consolidation of multilayered saturated soils subjected to time-dependent heating and loading
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作者 TANG Ke-jie WEN Min-jie +4 位作者 TU Yuan WU Wen-bing XIE Jia-hao LIU Kai-fu WU Da-zhi 《Journal of Central South University》 2025年第6期2239-2255,共17页
Heat transfers at the interface of adjacent saturated soil primarily through the soil particles and the water in the voids.The presence of water induces the contraction of heat flow lines at the interface,leading to t... Heat transfers at the interface of adjacent saturated soil primarily through the soil particles and the water in the voids.The presence of water induces the contraction of heat flow lines at the interface,leading to the emergence of the thermal contact resistance effect.In this paper,four thermal contact models were developed to predict the thermal contact resistance at the interface of multilayered saturated soils.Based on the theory of thermal-hydro-mechanical coupling,semi-analytical solutions of thermal consolidation subjected to time-dependent heating and loading were obtained by employing Laplace transform and its inverse transformation.Thermal consolidation characteristics of multilayered saturated soils under four different thermal contact models were discussed,and the effects of thermal resistance coefficient,partition thermal contact coefficient,and temperature amplitude on the thermal consolidation process were investigated.The outcomes indicate that the general thermal contact model results in the most pronounced thermal gradient at the interface,which can be degenerated to the other three thermal contact models.The perfect thermal contact model overestimates the deformation of the saturated soil during the thermal consolidation.Moreover,the effect of temperature on consolidation properties decreases gradually with increasing interfacial contact thermal resistance. 展开更多
关键词 multilayered saturated soils thermal consolidation thermal contact resistance time-dependent loading Laplace transform
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Investigation on dynamic response of liquid-filled cylindrical shellstructures under the action of combined blast and fragments loading
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作者 Zhujie Zhao Hailiang Hou +4 位作者 Dian Li Xiaowei Wu Yongqing Li Zhenghan Chen Linzhi Wu 《Defence Technology(防务技术)》 2025年第7期334-354,共21页
This study designs four types of liquid-filled cylindrical shell structures to investigate their protection characteristics against explosive shock waves and high-speed fragments.Bare charge and charge-driven prefabri... This study designs four types of liquid-filled cylindrical shell structures to investigate their protection characteristics against explosive shock waves and high-speed fragments.Bare charge and charge-driven prefabricated fragments are employed to examine the damage under blast shock waves and combined blast and fragments loading on various liquid-filled cylindrical shell structures.The test results are compared to numerical calculations and theoretical analysis for the structure's deformation,the liquid medium's movement,and the pressure waves'propagation characteristics under different liquid-filling methods.The results showed that the filling method influences the blast protection and the struc-ture's energy absorption performance.The external filling method reduces the structural deformation,and the internal filling method increases the damage effect.The gapped internal filling method improves the structure's energy absorption efficiency.The pressure wave loading on the liquid-filled cylindrical shell structure differs depending on filling methods.Explosive shock waves and high-speed fragments show a damage enhancement effect on the liquid-filled cylindrical shell structure,depending on the thickness of the internal liquid container layer.The specific impulse on the inner surface of the cylindrical shell positively correlates to the radial deformation of the cylindrical shell structure,and the external liquid layer limits the radial structural deformation. 展开更多
关键词 Blast wave Combined blast and fragments loading Filling method Liquid-filled structure Dynamic response
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A new dimensionless number for dynamic plastic deformation analysis of clamped circular plates subjected to underwater blast loading
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作者 Weizheng Xu Yu Huang +4 位作者 Tong Li Hao Tang Yexun Li Hua Fu Xianxu Zheng 《Defence Technology(防务技术)》 2025年第9期294-302,共9页
A new dimensionless number is proposed for dynamic plastic deformation analysis of clamped circular plates under underwater explosion loads by introducing dimensional analysis method to the basic dynamical governing e... A new dimensionless number is proposed for dynamic plastic deformation analysis of clamped circular plates under underwater explosion loads by introducing dimensional analysis method to the basic dynamical governing equations of circular plates.The relation between dimensionless final plastic deformation of circular plates and the new dimensionless number is established based on massive underwater explosion test data.Meanwhile,comparative analysis was discussed with two other published dimensionless parameters which indicated the new dimensionless number proposed in this paper is more effective and extensive to predict the dynamic plastic response of circular plates under underwater explosion condition. 展开更多
关键词 Dimensionless number Underwater blast loading Clamped circular plate Dynamic plastic deformation
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Dynamic response of polymethacrylimide foam sandwich structures with different core layers under water impact loading
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作者 Peilin Zhu Jili Rong +2 位作者 Shenglong Wang Zichao Chen Zifan Jiang 《Defence Technology(防务技术)》 2025年第7期203-222,共20页
Polymethacrylimide(PMI)foam has the highest specific stiffness and strength among polymer foams,with excellent radar-absorbing capabilities,which provide it with broad prospects in underwater ap-plications.To evaluate... Polymethacrylimide(PMI)foam has the highest specific stiffness and strength among polymer foams,with excellent radar-absorbing capabilities,which provide it with broad prospects in underwater ap-plications.To evaluate the impact resistance of PMI foam sandwich structures,the dynamic response and energy absorption characteristics of PMI foam sandwich structures with different core layers under various water impact loads were investigated using combined experimental and numerical methods.A fluid-structure interaction device with a diffusion angle was used for water impact testing of the PMI foam sandwich structures.The 3D-DIC technique was employed to process the deformation images of the sandwich-structure back panel captured by the high-speed cameras.Numerical simulations were performed to analyze the dynamic deformation process of the PMI foam core.The results indicated that the maximum deformation of the back panel exhibited a nonlinear relationship with the impulse.Below the critical impulse,the maximum deformation of the back panel plateaued,which was determined by the core density.Beyond the critical impulse,the rate of deformation increased with the impulse was governed by the core thickness.Compared with different sandwich panels,PMI foam sandwich struc-tures demonstrate significant advantages in terms of impact resistance under high-impulse conditions. 展开更多
关键词 PMI foam sandwich structure Underwater impact loading Impact resistance Energy absorption characteristics
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Crashworthiness design of concave polygonal CFRP tubes for eVTOL applications under multi-angle compression loading
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作者 Jie Fu Qiang Liu +1 位作者 Xiao Liu Yanqin Zhang 《Defence Technology(防务技术)》 2025年第10期100-115,共16页
The electric vertical takeoff and landing(e VTOL)aircraft shows great potential for rapid military personnel deployment on the battlefield.However,its susceptibility to control loss,complex crashes,and extremely limit... The electric vertical takeoff and landing(e VTOL)aircraft shows great potential for rapid military personnel deployment on the battlefield.However,its susceptibility to control loss,complex crashes,and extremely limited bottom energy-absorbing space demands higher comprehensive crashworthiness of its subfloor thin-walled structures.This study investigated the energy absorption capacity of novel concave polygonal carbon fiber reinforced plastics(CFRP)tubes under multi-angle collisions.Quasistatic compression experiments and finite element simulations were conducted to assess the failure mode and energy absorption.The influences of cross-section shapes,loading conditions,and geometry parameters on crashworthiness metrics were further analyzed.The results revealed that,under the similar weight,concave polygonal tubes exhibited superior energy absorption under axial loads compared to regular polygonal and circular tubes,attributed to the increased number of axial splits.However,both regular and concave polygonal tubes,particularly the latter,demonstrated reduced oblique energy absorption compared to traditional square tubes with the increasing ratio of SEA value decreased from 20%-16%.Notably,this reduction in energy absorption can be compensated for by the implementation of inward and outward crusher plugs,and with them,the concave polygonal tubes demonstrated outstanding overall crashworthiness performance under multiple loading conditions.This concave cross-sectional design methods could serve as a guidance for the development of the eVTOL subfloor. 展开更多
关键词 Carbon fiber reinforced plastics Concave polygonal tubes Multi-angle compression loading Energy absorption performance
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Analysis of meshing characteristics of planetary gear system considering tooth surface roughness and elastohydrodynamic lubrication
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作者 LIU Ning MA Hui +4 位作者 GUAN Hong ZHOU Sai-nan ZHAO Tian-yu CAO Peng WU Yu-ping 《Journal of Central South University》 2025年第7期2511-2534,共24页
The contact characteristics of the rough tooth surface during the meshing process are significantly affected by the lubrication state.The coupling effect of tooth surface roughness and lubrication on meshing character... The contact characteristics of the rough tooth surface during the meshing process are significantly affected by the lubrication state.The coupling effect of tooth surface roughness and lubrication on meshing characteristics of planetary gear is studied.An improved three-dimensional(3 D)anisotropic tooth surface roughness fractal model is proposed based on the experimental parameters.Considering asperity contact and elastohydrodynamic lubrication(EHL),the contact load and flexibility deformation of the tooth surface are derived,and the deformation compatibility equation of the 3 D loaded tooth contact analysis(3 D-LTCA)method is improved.The asperity of the tooth surface changes the system from EHL to mixed lubrication and reduces the stiffness of the oil film.Compared with the sun planet gear,the asperity has a greater effect on the meshing characteristics of the ring-planet gear.Compared with the proposed method,the comprehensive stiffness obtained by the traditional calculation method considering the lubrication effect is smaller,especially for the ring-planet gear.Compared with roughness,speed and viscosity,the meshing characteristics of planetary gears are most sensitive to torque. 展开更多
关键词 planetary gear tooth surface roughness three-dimensional loaded tooth contact analysis elastohydrodynamic lubrication meshing stiffness
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MiR-194-Loaded Gelatin Nanospheres Target MEF2C to Suppress Muscle Atrophy in Mechanical Unloading Model 被引量:1
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作者 张辰艳 杨长青 +3 位作者 刘杰 张葛 刘新利 尹大川 《医用生物力学》 CAS CSCD 北大核心 2021年第S01期80-80,共1页
There is still no effective therapy for muscle atrophy.It found that miR-194 was significantlydownregulated in muscle atrophy model.miR-194 could promote muscle differentiation,and also inhibit ubiquitin ligases.miR-1... There is still no effective therapy for muscle atrophy.It found that miR-194 was significantlydownregulated in muscle atrophy model.miR-194 could promote muscle differentiation,and also inhibit ubiquitin ligases.miR-194 loaded in gelatin nanosphere were injected into the muscle atrophy model to realize controlled release. 展开更多
关键词 ATROPHY loaded trophy
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Surface Pressure Loading Technology of Ship Structures 被引量:2
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作者 DAI Ze-yu WEI Peng-yu +3 位作者 CHEN Xiao-ping JIANG Ze CHEN Zhe TANG Qin 《船舶力学》 EI CSCD 北大核心 2024年第12期1940-1952,共13页
A hull structure is prone to local deformation and damage due to the pressure load on the surface.How to simulate surface pressure is an important issue in ship structure test.The loading mode of hydraulic actuator co... A hull structure is prone to local deformation and damage due to the pressure load on the surface.How to simulate surface pressure is an important issue in ship structure test.The loading mode of hydraulic actuator combined with high-pressure flexible bladder was proposed,and the numerical model of the loading device based on flexible bladder was established.The design and analysis method of high-pressure flexible bladder based on aramid-fiber reinforced thermoplastic polyurethane was proposed to break through the surface pressure loading technology of ship structures.The surface pressure loading system based on flexible bladder was developed.The ultimate strength verification test of the box girder under the combined action of bending moment and pressure was carried out to systematically verify the feasibility and applicability of the loading system.The results show that the surface pressure loading technology can be used well for applying uniform pressure to ship structures.Compared with the traditional surface loading methods,the improved device can be applied with horizontal constant pressure load,with rapid response and safe process,and the pressure load is always stable with the increase of the bending moment load during the test.The requirement for uniform loading in the comprehensive strength test of large structural models is satisfied and the accuracy of the test results is improved by this system. 展开更多
关键词 surface pressure load loading system ship structure strength test flexible bladder
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Calculating changes in fractal dimension of surface cracks to quantify how the dynamic loading rate affects rock failure in deep mining 被引量:31
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作者 GAO Ming-zhong ZHANG Jian-guo +3 位作者 LI Sheng-wei WANG Man WANG Ying-wei CUI Peng-fei 《Journal of Central South University》 SCIE EI CAS CSCD 2020年第10期3013-3024,共12页
The split-Hopkinson pressure bar(SHPB)and digital image correlation(DIC)techniques are combined to analyze the dynamic compressive failure process of coal samples,and the box fractal dimension is used to quantitativel... The split-Hopkinson pressure bar(SHPB)and digital image correlation(DIC)techniques are combined to analyze the dynamic compressive failure process of coal samples,and the box fractal dimension is used to quantitatively analyze the dynamic changes in the coal sample cracks under impact load conditions with different loading rates.The experimental results show that the fractal dimension can quantitatively describe the evolution process of coal fractures under dynamic load.During the dynamic compression process,the evolution of the coal sample cracks presents distinct stages.In the crack propagation stage,the fractal dimension increases rapidly with the progress of loading,and in the crack widening stage,the fractal dimension increases slowly with the progress of loading.The initiation of the crack propagation phase of the coal samples gradually occurs more quickly with increasing loading rate;the initial cracks appear earlier.At the same loading time point,when the loading rate is greater,the fractal dimension of the cracks observed in the coal sample is greater. 展开更多
关键词 fractal dimension loading rate impact load coal crack
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Experimental and numerical simulation of loading rate effects on failure and strain energy characteristics of coal-rock composite samples 被引量:32
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作者 MAQing TAN Yun-liang +3 位作者 LIU Xue-sheng ZHAO Zeng-hui FAN De-yuan PUREV Lkhamsuren 《Journal of Central South University》 SCIE EI CAS CSCD 2021年第10期3207-3222,共16页
The deformation and failure of coal and rock is energy-driving results according to thermodynamics.It is important to study the strain energy characteristics of coal-rock composite samples to better understand the def... The deformation and failure of coal and rock is energy-driving results according to thermodynamics.It is important to study the strain energy characteristics of coal-rock composite samples to better understand the deformation and failure mechanism of of coal-rock composite structures.In this research,laboratory tests and numerical simulation of uniaxial compressions of coal-rock composite samples were carried out with five different loading rates.The test results show that strength,deformation,acoustic emission(AE)and energy evolution of coal-rock composite sample all have obvious loading rate effects.The uniaxial compressive strength and elastic modulus increase with the increase of loading rate.And with the increase of loading rate,the AE energy at the peak strength of coal-rock composites increases first,then decreases,and then increases.With the increase of loading rate,the AE cumulative count first decreases and then increases.And the total absorption energy and dissipation energy of coal-rock composite samples show non-linear increasing trends,while release elastic strain energy increases first and then decreases.The laboratory experiments conducted on coal-rock composite samples were simulated numerically using the particle flow code(PFC).With careful selection of suitable material constitutive models for coal and rock,and accurate estimation and calibration of mechanical parameters of coal-rock composite sample,it was possible to obtain a good agreement between the laboratory experimental and numerical results.This research can provide references for understanding failure of underground coalrock composite structure by using energy related measuring methods. 展开更多
关键词 coal-rock composite samples uniaxial compression loading rate acoustic emission energy evolution
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