The topic of improving the mechanical stability of external cavity diode lasers(ECDLs)has recently attracted widespread attention and interest.The use of corner-cube-array(CCA)-based resonators provides a potential so...The topic of improving the mechanical stability of external cavity diode lasers(ECDLs)has recently attracted widespread attention and interest.The use of corner-cube-array(CCA)-based resonators provides a potential solution for this purpose,although continuous oscillation at super large incident angle remains challenging.In this work,we employ the CCA resonator to generate continuous oscillation within±20°angular misalignment of cavity mirror in experiment.On the basis of retroreflection theory,the retroreflectivity of a CCA is analyzed by using optical simulation software.Notably,the experiment verifies the advantage of using a CCA over a plane mirror in laser resonator,thereby providing a promising approach for ECDLs.The threshold characteristic curves measured at different incident angles in the experiment verify that the CCA possesses an obvious anti-angle misalignment performance.This research introduces an alternative solution of using CCA resonator instead of parallel plane cavity,thereby realizing an adjustment-free ECDL with enhanced mechanical stability.展开更多
A laser scanning confocal imaging-surface plasmon resonance （LSCI-SPR） instrument integrated with a wavelength-dependent surface plasmon resonance （SPR） sensor and a laser scanning confocal microscopy （LSCM） is ...A laser scanning confocal imaging-surface plasmon resonance （LSCI-SPR） instrument integrated with a wavelength-dependent surface plasmon resonance （SPR） sensor and a laser scanning confocal microscopy （LSCM） is built to detect the bonding process of human IgG and fluorescent-labeled affinity purified antibodies in real time. The shifts of resonant wavelength at different reaction time stages are obtained by SPR, corresponding well with the changes of the fluorescence intensity collected by using LSCM. The instrument shows the merits of the combination and complementation of the SPR and LSCM, with such advantages as quantificational analysis, high spatial resolution and real time monitor, which are of great importance for practical applications in biosensor and life science.展开更多
基金supported by the Natural Science Foundation of Jiangsu Province(Grant No.BK20240613)Jiangsu Province’s“Innovation and Entrepreneurship Doctor”Program(Grant No.JSSCBS20230088)+4 种基金Natural Science Foundation of Nanjing University of Posts and Telecommunications(Grant No.NY224123)Natural Science Research Start-up Foundation of Recruiting Talents of Nanjing University of Posts and Telecommunications(Grant No.NY222112)Beijing Nova Program(Grant No.20240484696)Wenzhou Major Science and Technology Innovation Key Project(Grant No.ZG2020046)INNOVATION Program for Quantum Science and Technology(Grant No.2021ZD0303200)。
文摘The topic of improving the mechanical stability of external cavity diode lasers(ECDLs)has recently attracted widespread attention and interest.The use of corner-cube-array(CCA)-based resonators provides a potential solution for this purpose,although continuous oscillation at super large incident angle remains challenging.In this work,we employ the CCA resonator to generate continuous oscillation within±20°angular misalignment of cavity mirror in experiment.On the basis of retroreflection theory,the retroreflectivity of a CCA is analyzed by using optical simulation software.Notably,the experiment verifies the advantage of using a CCA over a plane mirror in laser resonator,thereby providing a promising approach for ECDLs.The threshold characteristic curves measured at different incident angles in the experiment verify that the CCA possesses an obvious anti-angle misalignment performance.This research introduces an alternative solution of using CCA resonator instead of parallel plane cavity,thereby realizing an adjustment-free ECDL with enhanced mechanical stability.
基金supported by the Instrument Developing Project of the Chinese Academy of Sciences (Grant No.YZ200740)the National Natural Science Foundation of China (Grant Nos.60978034 and 10974019)the National High Technology Research and Development Program of China (Grant No.2009AA03Z318)
文摘A laser scanning confocal imaging-surface plasmon resonance （LSCI-SPR） instrument integrated with a wavelength-dependent surface plasmon resonance （SPR） sensor and a laser scanning confocal microscopy （LSCM） is built to detect the bonding process of human IgG and fluorescent-labeled affinity purified antibodies in real time. The shifts of resonant wavelength at different reaction time stages are obtained by SPR, corresponding well with the changes of the fluorescence intensity collected by using LSCM. The instrument shows the merits of the combination and complementation of the SPR and LSCM, with such advantages as quantificational analysis, high spatial resolution and real time monitor, which are of great importance for practical applications in biosensor and life science.
