A fast encoding algorithm based on the mean square error （MSE） distortion for vector quantization is introduced. The vector, which is effectively constructed with wavelet transform （WT） coefficients of images, can...A fast encoding algorithm based on the mean square error （MSE） distortion for vector quantization is introduced. The vector, which is effectively constructed with wavelet transform （WT） coefficients of images, can simplify the realization of the non-linear interpolated vector quantization （NLIVQ） technique and make the partial distance search （PDS） algorithm more efficient. Utilizing the relationship of vector L2-norm and its Euclidean distance, some conditions of eliminating unnecessary codewords are obtained. Further, using inequality constructed by the subvector L2-norm, more unnecessary codewords are eliminated. During the search process for code, mostly unlikely codewords can be rejected by the proposed algorithm combined with the non-linear interpolated vector quantization technique and the partial distance search technique. The experimental results show that the reduction of computation is outstanding in the encoding time and complexity against the full search method.展开更多
In order to optionally regulate embedding capacity and embedding transparency according to user's requirements in voice-over-IP(VoIP) steganography,a dynamic matrix encoding strategy(DMES) was presented.Differing ...In order to optionally regulate embedding capacity and embedding transparency according to user's requirements in voice-over-IP(VoIP) steganography,a dynamic matrix encoding strategy(DMES) was presented.Differing from the traditional matrix encoding strategy,DMES dynamically chose the size of each message group in a given set of adoptable message sizes.The appearance possibilities of all adoptable sizes were set in accordance with the desired embedding performance(embedding rate or bit-change rate).Accordingly,a searching algorithm that could provide an optimal combination of appearance possibilities was proposed.Furthermore,the roulette wheel algorithm was employed to determine the size of each message group according to the optimal combination of appearance possibilities.The effectiveness of DMES was evaluated in StegVoIP,which is a typical covert communication system based on VoIP.The experimental results demonstrate that DMES can adjust embedding capacity and embedding transparency effectively and flexibly,and achieve the desired embedding performance in any case.For the desired embedding rate,the average errors are not more than 0.000 8,and the standard deviations are not more than 0.002 0;for the desired bit-change rate,the average errors are not more than 0.001 4,and the standard deviations are not more than 0.002 6.展开更多
Oncolysate, a debris of tumor cells, has been provento be effective in tumor active immunotherapy, it wasreported that the vaccinia virus, especially recombinantvaccinia viruses encoding human IL-2 (rVV-IL-2 ),enhance...Oncolysate, a debris of tumor cells, has been provento be effective in tumor active immunotherapy, it wasreported that the vaccinia virus, especially recombinantvaccinia viruses encoding human IL-2 (rVV-IL-2 ),enhanced the immunogenicity of transfected tumor cells.In this experiment, the murine melanoma cell B16-F10oncolysates trans fected by rVV-IL-2 (IL-2VBO) wereused as vaccine. The IL-2VBO or TK-VBO was preparedby incubating B16-F10 cells with rVV-IL-2 or rVV-TK展开更多
Fountain codes are considered to be a promising coding technique in underwater acoustic communication（UAC） which is challenged with the unique propagation features of the underwater acoustic channel and the harsh ma...Fountain codes are considered to be a promising coding technique in underwater acoustic communication（UAC） which is challenged with the unique propagation features of the underwater acoustic channel and the harsh marine environment. And Luby transform（LT） codes are the first codes fully realizing the digital fountain concept. However, in conventional LT encoding/decoding algorithms, due to the imperfect coverage（IC） of input symbols and short cycles in the generator matrix, stopping sets would occur and terminate the decoding. Thus, the recovery probability is reduced,high coding overhead is required and decoding delay is increased.These issues would be disadvantages while applying LT codes in underwater acoustic communication. Aimed at solving those issues, novel encoding/decoding algorithms are proposed. First,a doping and non-uniform selecting（DNS） encoding algorithm is proposed to solve the IC and the generation of short cycles problems. And this can reduce the probability of stopping sets occur during decoding. Second, a hybrid on the fly Gaussian elimination and belief propagation（OFG-BP） decoding algorithm is designed to reduce the decoding delay and efficiently utilize the information of stopping sets. Comparisons via Monte Carlo simulation confirm that the proposed schemes could achieve better overall decoding performances in comparison with conventional schemes.展开更多
A predicted tau glutathione S-transferase(GST) subunit encoding gene,named GhGST,was isolated from Gossypium hirsutum with RACE method from SSH library based on Verticillium
Direct gene transfer into somatic tissue in vivo is adeveloping technology with potential application forcancer gene therapy. Retrovirus vector, which was aneffective vehicle, still has some disadvantages ingenerating...Direct gene transfer into somatic tissue in vivo is adeveloping technology with potential application forcancer gene therapy. Retrovirus vector, which was aneffective vehicle, still has some disadvantages ingenerating high titer recombinant vectors andmanipulating to mediate in viro gene transfer. In thispaper, recombinant vaccinia virus vector encoding展开更多
We have constructed three recombinantadenoviruses encoding RA538, p53 or p16 respec-tively. These recombinant adenoviruses are able toexpress RA538, p53 or p16 in infected human cancercells. The transduction efficienc...We have constructed three recombinantadenoviruses encoding RA538, p53 or p16 respec-tively. These recombinant adenoviruses are able toexpress RA538, p53 or p16 in infected human cancercells. The transduction efficiency assay showed thatthe infected cancer cells inoculated with theserecombinant adenoviruses at MOI of 25 or greaterexhibited 100% transduction efficiency. The growthrates and colony formation of cancer cells infectedwith these recombinant adenoviruses were展开更多
To improve the error correction performance, an innovative encoding structure with tail-biting for spinal codes is designed. Furthermore, an adaptive forward stack decoding(A-FSD) algorithm with lower complexity for s...To improve the error correction performance, an innovative encoding structure with tail-biting for spinal codes is designed. Furthermore, an adaptive forward stack decoding(A-FSD) algorithm with lower complexity for spinal codes is proposed. In the A-FSD algorithm, a flexible threshold parameter is set by a variable channel state to narrow the scale of nodes accessed. On this basis, a new decoding method of AFSD with early termination(AFSD-ET) is further proposed. The AFSD-ET decoder not only has the ability of dynamically modifying the number of stored nodes, but also adopts the early termination criterion to curtail complexity. The complexity and related parameters are verified through a series of simulations. The simulation results show that the proposed spinal codes with tail-biting and the AFSD-ET decoding algorithms can reduce the complexity and improve the decoding rate without sacrificing correct decoding performance.展开更多
Plants have developed a complicated defense mechanism during evolution to resist the harmful pathogens they encountered.The mechanism involves the interaction of the plant resistance(R)
The linear encoding of a quadtree is an efficient way to represent the quadtree. In this paper, an improved linear quadtree, a cell linear quadtree, is proposed, in which its redundant storage is eliminated and the co...The linear encoding of a quadtree is an efficient way to represent the quadtree. In this paper, an improved linear quadtree, a cell linear quadtree, is proposed, in which its redundant storage is eliminated and the concept of a cell is introduced. Therefore, it has higher storage efficiency than a conventional linear quadtree.展开更多
To solve the problem of identification and measurement of two projectiles hitting the target at the same time,this paper proposes a projectile coordinate test method combining three photoelectric encoder detection scr...To solve the problem of identification and measurement of two projectiles hitting the target at the same time,this paper proposes a projectile coordinate test method combining three photoelectric encoder detection screens,and establishes a coordinate calculation model for two projectiles to reach the same detection screen at the same time.The design method of three photoelectric encoder detection screens and the position coordinate recognition algorithm of the blocked array photoelectric detector when projectile passing through the photoelectric encoder detection screen are studied.Using the screen projection method,the intersected linear equation of the projectile and the line laser with the main detection screen as the core coordinate plane is established,and the projectile coordinate data set formed by any two photoelectric encoder detection screens is constructed.The principle of minimum error of coordinate data set is used to determine the coordinates of two projectiles hitting the target at the same time.The rationality and feasibility of the proposed test method are verified by experiments and comparative tests.展开更多
人类基因组计划完成以来,科学家们一直在努力阐释基因组信息所代表的生物学意义。自2003年开始,美国国家人类基因组研究所(National Human Genome Research Institute,NHGRI)投资近3亿美元启动"DNA元件百科全书(Encyclopedia of DN...人类基因组计划完成以来,科学家们一直在努力阐释基因组信息所代表的生物学意义。自2003年开始,美国国家人类基因组研究所(National Human Genome Research Institute,NHGRI)投资近3亿美元启动"DNA元件百科全书(Encyclopedia of DNA Elements,ENCODE)"计划,集结了来自美国、中国、英国、日本、西班牙和新加坡等国家的32个实验室的440余名科学家,共同鉴定并分析人类基因组中所有的功能调控元件。高通量测序技术等实验手段的发展和生物信息学技术的不断完善使得ENCODE计划取得了丰硕的成果:确定了甲基化和组蛋白修饰等表观修饰区域及其对染色质结构的作用,进而确定染色质结构的改变影响基因表达;确定了转录因子及其结合位点的信息,并构建了转录因子调控网络;进一步修订更新了假基因和非编码RNA数据库;并确定了调控序列的单核苷酸多态性(Single nucleotide polymorphism,SNP)并与疾病相关联。这些发现一方面有助于系统解析基因和基因组信息、调控元件的调控作用以及非编码区转录调控等分子机制;同时也将为转化医学等生命科学研究领域提供丰富的数据来源。文章综述了高通量测序技术等实验手段的发展和生物信息学技术的不断完善对ENCODE计划的贡献、表观遗传学研究与ENCODE计划的关联性、ENCODE计划的主要科学成果等,同时展望了ENCODE计划对基础医学、临床医学和转化医学等生命科学研究领域的巨大推动作用。展开更多
基金the National Natural Science Foundation of China (60602057)the NaturalScience Foundation of Chongqing Science and Technology Commission (2006BB2373).
文摘A fast encoding algorithm based on the mean square error （MSE） distortion for vector quantization is introduced. The vector, which is effectively constructed with wavelet transform （WT） coefficients of images, can simplify the realization of the non-linear interpolated vector quantization （NLIVQ） technique and make the partial distance search （PDS） algorithm more efficient. Utilizing the relationship of vector L2-norm and its Euclidean distance, some conditions of eliminating unnecessary codewords are obtained. Further, using inequality constructed by the subvector L2-norm, more unnecessary codewords are eliminated. During the search process for code, mostly unlikely codewords can be rejected by the proposed algorithm combined with the non-linear interpolated vector quantization technique and the partial distance search technique. The experimental results show that the reduction of computation is outstanding in the encoding time and complexity against the full search method.
基金Project(2009AA01A402) supported by the National High-Tech Research and Development Program of ChinaProject(NCET-06-0650) supported by Program for New Century Excellent Talents in University Project(IRT-0725) supported by Program for Changjiang Scholars and Innovative Research Team in Chinese University
文摘In order to optionally regulate embedding capacity and embedding transparency according to user's requirements in voice-over-IP(VoIP) steganography,a dynamic matrix encoding strategy(DMES) was presented.Differing from the traditional matrix encoding strategy,DMES dynamically chose the size of each message group in a given set of adoptable message sizes.The appearance possibilities of all adoptable sizes were set in accordance with the desired embedding performance(embedding rate or bit-change rate).Accordingly,a searching algorithm that could provide an optimal combination of appearance possibilities was proposed.Furthermore,the roulette wheel algorithm was employed to determine the size of each message group according to the optimal combination of appearance possibilities.The effectiveness of DMES was evaluated in StegVoIP,which is a typical covert communication system based on VoIP.The experimental results demonstrate that DMES can adjust embedding capacity and embedding transparency effectively and flexibly,and achieve the desired embedding performance in any case.For the desired embedding rate,the average errors are not more than 0.000 8,and the standard deviations are not more than 0.002 0;for the desired bit-change rate,the average errors are not more than 0.001 4,and the standard deviations are not more than 0.002 6.
文摘Oncolysate, a debris of tumor cells, has been provento be effective in tumor active immunotherapy, it wasreported that the vaccinia virus, especially recombinantvaccinia viruses encoding human IL-2 (rVV-IL-2 ),enhanced the immunogenicity of transfected tumor cells.In this experiment, the murine melanoma cell B16-F10oncolysates trans fected by rVV-IL-2 (IL-2VBO) wereused as vaccine. The IL-2VBO or TK-VBO was preparedby incubating B16-F10 cells with rVV-IL-2 or rVV-TK
基金supported by the National Natural Science Foundation of China(61371099)the Fundamental Research Funds for the Central Universities of China(HEUCF150812/150810)
文摘Fountain codes are considered to be a promising coding technique in underwater acoustic communication（UAC） which is challenged with the unique propagation features of the underwater acoustic channel and the harsh marine environment. And Luby transform（LT） codes are the first codes fully realizing the digital fountain concept. However, in conventional LT encoding/decoding algorithms, due to the imperfect coverage（IC） of input symbols and short cycles in the generator matrix, stopping sets would occur and terminate the decoding. Thus, the recovery probability is reduced,high coding overhead is required and decoding delay is increased.These issues would be disadvantages while applying LT codes in underwater acoustic communication. Aimed at solving those issues, novel encoding/decoding algorithms are proposed. First,a doping and non-uniform selecting（DNS） encoding algorithm is proposed to solve the IC and the generation of short cycles problems. And this can reduce the probability of stopping sets occur during decoding. Second, a hybrid on the fly Gaussian elimination and belief propagation（OFG-BP） decoding algorithm is designed to reduce the decoding delay and efficiently utilize the information of stopping sets. Comparisons via Monte Carlo simulation confirm that the proposed schemes could achieve better overall decoding performances in comparison with conventional schemes.
文摘A predicted tau glutathione S-transferase(GST) subunit encoding gene,named GhGST,was isolated from Gossypium hirsutum with RACE method from SSH library based on Verticillium
文摘Direct gene transfer into somatic tissue in vivo is adeveloping technology with potential application forcancer gene therapy. Retrovirus vector, which was aneffective vehicle, still has some disadvantages ingenerating high titer recombinant vectors andmanipulating to mediate in viro gene transfer. In thispaper, recombinant vaccinia virus vector encoding
文摘We have constructed three recombinantadenoviruses encoding RA538, p53 or p16 respec-tively. These recombinant adenoviruses are able toexpress RA538, p53 or p16 in infected human cancercells. The transduction efficiency assay showed thatthe infected cancer cells inoculated with theserecombinant adenoviruses at MOI of 25 or greaterexhibited 100% transduction efficiency. The growthrates and colony formation of cancer cells infectedwith these recombinant adenoviruses were
基金supported by the National Natural Science Foundation of China (61701020)the Scientific and Technological Innovation Foundation of Shunde Graduate School,USTB (BK19BF009)。
文摘To improve the error correction performance, an innovative encoding structure with tail-biting for spinal codes is designed. Furthermore, an adaptive forward stack decoding(A-FSD) algorithm with lower complexity for spinal codes is proposed. In the A-FSD algorithm, a flexible threshold parameter is set by a variable channel state to narrow the scale of nodes accessed. On this basis, a new decoding method of AFSD with early termination(AFSD-ET) is further proposed. The AFSD-ET decoder not only has the ability of dynamically modifying the number of stored nodes, but also adopts the early termination criterion to curtail complexity. The complexity and related parameters are verified through a series of simulations. The simulation results show that the proposed spinal codes with tail-biting and the AFSD-ET decoding algorithms can reduce the complexity and improve the decoding rate without sacrificing correct decoding performance.
文摘Plants have developed a complicated defense mechanism during evolution to resist the harmful pathogens they encountered.The mechanism involves the interaction of the plant resistance(R)
文摘The linear encoding of a quadtree is an efficient way to represent the quadtree. In this paper, an improved linear quadtree, a cell linear quadtree, is proposed, in which its redundant storage is eliminated and the concept of a cell is introduced. Therefore, it has higher storage efficiency than a conventional linear quadtree.
基金supported by National Natural Science Foundation of China(Grant No.62073256)Shaanxi Provincial Science and Technology Department(Grant No.2023-YBGY-342)。
文摘To solve the problem of identification and measurement of two projectiles hitting the target at the same time,this paper proposes a projectile coordinate test method combining three photoelectric encoder detection screens,and establishes a coordinate calculation model for two projectiles to reach the same detection screen at the same time.The design method of three photoelectric encoder detection screens and the position coordinate recognition algorithm of the blocked array photoelectric detector when projectile passing through the photoelectric encoder detection screen are studied.Using the screen projection method,the intersected linear equation of the projectile and the line laser with the main detection screen as the core coordinate plane is established,and the projectile coordinate data set formed by any two photoelectric encoder detection screens is constructed.The principle of minimum error of coordinate data set is used to determine the coordinates of two projectiles hitting the target at the same time.The rationality and feasibility of the proposed test method are verified by experiments and comparative tests.
文摘人类基因组计划完成以来,科学家们一直在努力阐释基因组信息所代表的生物学意义。自2003年开始,美国国家人类基因组研究所(National Human Genome Research Institute,NHGRI)投资近3亿美元启动"DNA元件百科全书(Encyclopedia of DNA Elements,ENCODE)"计划,集结了来自美国、中国、英国、日本、西班牙和新加坡等国家的32个实验室的440余名科学家,共同鉴定并分析人类基因组中所有的功能调控元件。高通量测序技术等实验手段的发展和生物信息学技术的不断完善使得ENCODE计划取得了丰硕的成果:确定了甲基化和组蛋白修饰等表观修饰区域及其对染色质结构的作用,进而确定染色质结构的改变影响基因表达;确定了转录因子及其结合位点的信息,并构建了转录因子调控网络;进一步修订更新了假基因和非编码RNA数据库;并确定了调控序列的单核苷酸多态性(Single nucleotide polymorphism,SNP)并与疾病相关联。这些发现一方面有助于系统解析基因和基因组信息、调控元件的调控作用以及非编码区转录调控等分子机制;同时也将为转化医学等生命科学研究领域提供丰富的数据来源。文章综述了高通量测序技术等实验手段的发展和生物信息学技术的不断完善对ENCODE计划的贡献、表观遗传学研究与ENCODE计划的关联性、ENCODE计划的主要科学成果等,同时展望了ENCODE计划对基础医学、临床医学和转化医学等生命科学研究领域的巨大推动作用。
